Abstract: The present invention relates to a sunscreen formulation which exhibits superior ultraviolet protection and water resistance than prior art sunscreen compositions. The sunscreen formulation comprises (a) a dispersion comprising a sunscreen active agent and (b) a base composition comprising a rheological modifying agent and water. The sunscreen formulation is substantially free of surfactants. According to a preferred embodiment, the sunscreen active agent is ethylhexylmethoxycinnamate, butylmethoxydibenzoylmethane, or a combination thereof. The sunscreen formulation preferably comprises a phosphorylated starch derivative as a rheological modifying agent. Another embodiment of the present invention is a method of protecting skin or hair from ultraviolet radiation by applying an effective amount of the sunscreen formulation of the present invention to the skin or hair.

Abstract: A method and system for selecting and producing a customized cosmetic or pharmaceutical formulation is disclosed below. The system can be implemented in an Internet based system or a stand-alone version, such as a Kiosk. An improved method of custom formulation is presented which utilizes the user's preferences and profile, as well as external factors. The customized formulation can be directed to a manufacturing facility for on-demand production. Alternatively, a printout of the formulation can be provided for subsequent use at point-of-sale locations, such as a cosmetics store or a pharmacy. The custom formulation software can also be provided in conjunction with a cosmetics manufacturing kit for use in home or business application.

Abstract: Disclosed are methods for preparing dispersions containing physiologically active or ingredients or aesthetic modifiers, and optionally containing vehicles, including solvents. The dispersions are prepared using high pressure/high shear methods.

Abstract: The present invention provides an oil-in-water wax dispersion comprising one or more waxes or hydrophobic semi-solids, a dispersion initiator, optionally oen or more plasticizing agents or solvents and/or co-solvents, and water. The invention also provides a method for preparing these oil-in-water wax dispersions and their use in topical, oral anal, ophthalmic, vaginal, otic and nasal formulations.

Abstract: Disclosed are methods for preparing topical compositions with enhanced barrier properties comprising dispersions of hydrophobic skin protective agents.

Abstract: The present invention relates to a sunscreen formulation which exhibits superior ultraviolet protection and water resistance than prior art sunscreen compositions. The sunscreen formulation comprises (a) a dispersion comprising a sunscreen active agent and (b) a base composition comprising a rheological modifying agent and water. The sunscreen formulation is bustantially free of surfactants. According to a preferred embodiment, the sunscreen active agent is ethylhexylmethoxycinnamate, butylmethoxy-dibenzoylmethane, or a combination thereof. The sunscreen formulation preferably comprises a phosphorylated starch derivative as a rheological modifying agent. Another embodiment of the present invention is a method of protecting skin or hair from ultraviolet radiation by applying an effective amount of the sunscreen formulation of the present invention to the skin or hair.

Abstract: Disclosed are methods for preparing surfactant free dispersions of hydrophobic fluids and hydrophobic rheological modifying agents which are used to modify the aesthetic properties of cosmetic and pharmaceutical topical compositions. The dispersions are prepared using high pressure/high shear methods. In particular, the dispersions comprise polyisobutene gel or silicone gel.

Abstract: The present invention relates to a composition for topical, oral, nasal, anal, ophthalmic, or vaginal application comprising a base composition and at least one dispersion comprising suspended particles of a hydrophobic active agent, a hydrophobic adjuvant, or a combination thereof. The base composition comprises a rheology modifying agent and water. The composition is substantially free of emulsifying surfactants and the suspended particles generally have a diameter less than about 500 or 1,000 nm. Another embodiment is a method of preparing a composition comprising mixing the aforementioned base composition with the aforementioned dispersion. Mixing may be performed with a propeller mixer or manually, i.e., by hand. Since the topical dispersion is simple and quick to prepare, custom cosmetic compositions may be prepared at the point of sale for customers. Prior to the present invention, such products would take hours to be prepared.

Abstract: Disclosed are stable, homogeneous dispersions, comprising (a) from about 20 to 90% by weight of a first composition comprising (i) about 60-95% by weight of a first polar solvent, (ii) about 0-40% by weight of one or more second polar solvents, and (iii) water soluble components of a first natural product; and (b) from about 10 to 60% by weight of a second composition comprising: (i) one or more apolar solvents, and (ii) oil soluble organic components of a second natural product; and (c) from about 0.01 to 8% by weight of a non-surface active lipid phosphate or a surface active agent. Also disclosed are methods of forming the stable, homogeneous dispersions of the invention, comprising forming a first composition comprising water soluble components of a first natural product; forming a second composition comprising oil soluble organic components of a second natural product; mixing the compositions and subjecting the mixture to high pressure high shear processing to form a stable, homogeneous dispersion.

Abstract: Disclosed are stable, homogeneous dispersions, comprising (a) from about 20 to 90% by weight of a first composition comprising (i) about 60-95% by weight of a first polar solvent, (ii) about 0-40% by weight of one or more second polar solvents, and (iii) water soluble components of a first natural product; and (b) from about 10 to 60% by weight of a second composition comprising: (i) one or more apolar solvents, and (ii) oil soluble organic components of a second natural product; and (c) from about 0.01 to 80% by weight of a non-surface active lipid phosphate or a surface active agent. Also disclosed are methods of forming the stable, homogeneous dispersions of the invention, comprising forming a first composition comprising water soluble components of a first natural product; forming a second composition comprising oil soluble organic components of a second natural product; mixing the compositions and subjecting the mixture to high pressure high shear processing to form a stable, homogeneous dispersion.

Abstract: A method and system for selecting and producing a customized cosmetic or pharmaceutical formulation is disclosed below. The system can be implemented in an Internet based system or a stand-alone version, such as a Kiosk. An improved method of custom formulation is presented which utilizes the user's preferences and profile, as well as external factors. The customized formulation can be directed to a manufacturing facility for on-demand production. Alternatively, a printout of the formulation can be provided for subsequent use at point-of-sale locations, such as a cosmetics store or a pharmacy. The custom formulation software can also be provided in conjunction with a cosmetics manufacturing kit for use in home or business application.

Abstract: Disclosed are stable compositions which are effective as skin whitening agents, comprising alpha, beta or gamma substituted mono-, di or polyhydroxy or polycarboxy carboxylic acids; mono-, di, tri or polyhydroxy alkyl compound; and effective amounts of an inhibitor of tyrosinase and a pigmentation reversing reagent. Also disclosed are methods of forming stable compositions of the type described above.

Abstract: The present invention provides for vitamin A derivative selected from the group consisting of retinol, retinyl ester and any combination thereof incorporated into liposomes formed with alkylammonium fatty acid salts, and methods for manufacturing same. The liposomes of the invention may deliver vitamin A derivative materials at the occurrence of a preset triggering condition. Preferred liposomes of the invention are cationic liposomes. The preferred liposomes of the invention are formed with alkylammonium fatty acid salts, e.g., trialkylammonium fatty acid salts of long chain amides. The encapsulated vitamin A derivative is thus stabilized by the liposomes. The present invention thus also provides a method of stabilizing vitamin A derivative be encapsulation in such liposomes. The liposomes of the invention are used to provide topical skin treatment formulations useful in the treatment of skin.

Abstract: Disclosed is an anionic shampoo-conditioning composition comprising an oily conditioning agent, a shampooing agent, a carboxyvinyl polymer, a cationic conditioning agent, and water. The carboxyvinyl polymer has a large proportion of carboxyl monomeric groups and a small proportion of long-chain alkyl monomeric units, and is crosslinked to a small degree. Further disclosed is a process for making the above composition and a method for applying it to hair. The composition provides enhanced conditioning properties utilizing both oily and cationic conditioning agents in combination with an anionic carboxyvinyl polymer while maintaining stability and dispersion.

Abstract: Disclosed is an improved reducing solution comprising: a) from about 1.0% to about 11.0% by weight of cysteamino hydrochloride; b) from about 1.0% to about 24% by weight of a reducing agent selected from a group consisting of salts and esters of thioglycolic acid, L-cysteine, thiolactic acid, and thiomaleic acid, dithioerythreitol, and dithiothyreitol; c) from about 0.5% to about 7% by weight of isoascorbic acid; d) a base in amounts sufficient to adjust the pH from about 6.5 to about 8.5; and e) water in amount sufficient to total 100 percent of the solution; the weight percents being based upon the total weight of the solution.

Abstract: A water activated solid, emollient preparation is disclosed, said preparation having a homogenous crystal/gel matrix which is capable of incorporating up to 30% by weight of emollient and holding it in a solid form. When the preparation is rubbed on wet skin, it deposits an elegant occlusive emollient film. A method of pouring and cooling said product into bars is also disclosed.

Abstract: Stable cosmetic compositions comprising ascorbic acid dissolved in at least two co-solvents, one of which comprises water, the other of which comprises an organic solvent miscible with water, or a blend of water miscible organic solvents. The compositions are adapted to be topically applied to the skin to impart appearance benefits thereto.

Abstract: Stable retinol compositions are disclosed. The compositions comprise retinol, a volatile silicone and a mutual solvent for the retinol and silicone. Preferred compositions contain retinol, cyclomethicone and ethanol.Were the retinol level in the compositions is between 0.005 and 1.0 weight percent, the compositions may be topically applied to the skin in areas where fine lines, wrinkles or other signs of aging exist. Such topical application results in a reduction in wrinkles and fine lines and improves skin quality. Where the compositions contain more than 0.005 to 1.0 weight percent retinol they may be diluted with cosmetically acceptable carriers or vehicles, preferably water in oil emulsions to reduce the retinol level and topically applied.