Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.

Abstract: The present disclosure relates to devices that aid a user in ceasing bruxism. The devices may be placed between a user's teeth, such as during sleep, and alert the user when the user clenches his/her teeth. In an aspect, a device includes a housing containing a battery power source, a vibration device, and an electrical contact mechanism having a movable element which closes a circuit to actuate the vibration device. A disk-shaped portion adapted to be emplaced in a person's mouth between a cheek and adjacent teeth is disposed around the housing. A resilient bite portion extends from the housing and is adapted to be emplaced between upper and lower teeth. A compressible element is disposed in the bite portion and causes the movable element of the electrical contact to close to actuate the vibration device in response to compression of the bite portion.

Abstract: Apparatus and associated methods relate to training FIR filter coefficients by deconvolving a first input signal and a second input signal in the frequency domain, both of the signals being generated in response to an undetermined broadband excitation applied to an acoustic body instrument, until a fidelity of the second signal convolved with the trained coefficients meets predetermined fidelity criteria relative to the first signal. In an illustrative example, a musical instrument pickup signal and a microphone signal from the musical instrument may be sampled, segmented, and transformed to the frequency domain. FIR filter coefficients may be, for example, trained by block deconvolution in the frequency domain of the microphone signal and the pickup signal. In various examples, the trained FIR filter coefficients may adapt the pickup signal to mimic microphone performance, including full-body acoustic content.

Abstract: An implantable fixation device for rejoining opposed portions of a separated bone. The device including two corresponding plates that are configured to be aligned and coupled to a bone, such as a sternum, pre-resection of the bone or prior to cutting/separating the bone. The placement of the corresponding plates provides a gap between the edges of the plates that face one another allowing for and guiding a cutting tool for separating the bone. After the bone has been cut and the desired surgical procedure performed, the plates also assist in realigning and fixation of the bone portions. At least one plate includes a ratchet mechanism that is configured to tighten a locking element and draw the two plates together and into alignment with one another.

Abstract: A method for maintaining pressure in a wellbore during drilling operations is disclosed. The method includes the steps of providing fluid from a reservoir through a drill string, circulating the fluid from the drill string to an annulus between the drill string and the wellbore, isolating pressure in the annulus, measuring pressure in the annulus, calculating a set point backpressure, applying back pressure to the annulus based on the set point back pressure, diverting fluid from the annulus to a controllable choke, controllably bleeding pressurized fluid from the annulus, separating solids from the fluid, and directing the fluid to the reservoir. An apparatus for maintaining pressure in a wellbore during drilling operations that includes an adjustable choke for controllably bleeding off pressurized fluid from the wellbore annulus. A backpressure pump for applying a set point backpressure, and a processor for controlling the adjustable choke and backpressure pump are also disclosed.

Abstract: A tool bit case includes a housing and a tool bit retainer pivotally coupled to the housing. The tool bit retainer includes a retainer housing having a plurality of tool bit apertures configured to receive a plurality of tool bits, and a locking mechanism moveably coupled to the retainer housing between a first position, in which the locking mechanism engages the plurality of tool bits to inhibit removal of the plurality of tool bits from the retainer housing, and a second position, in which the locking mechanism disengages the plurality of tool bits to allow removal of the plurality of tool bits from the retainer housing.

Abstract: Various embodiments of the present technology provide compositions and methods for a sweetener composition comprising stevia leaf extract, stevia glycosides, and/or Luo Han Guo fruit extract. The sweetener composition provides enhanced taste and/or flavor properties as compared to other non-caloric or low-caloric sweeteners. The sweetener composition has a reduced aftertaste relative to stevia leaf extract and/or purified steviol glycoside. The sweetener composition may be formulated into any edible sweetened substances.

Abstract: A vehicle system is provided that includes a sound augmentation system with a sound augmentation generator that produces an augmented audio output to drive at least one audio output based on a transfer function. The vehicle system also includes a sound augmentation system health monitor that determines a current performance level of the sound augmentation system based on at least one audio input and a feedback of the augmented audio output, and triggers a transfer function update prompt based on a difference between the current performance level and an expected performance level being at a threshold level. A user interface outputs the transfer function update prompt and receives a transfer function calibration request in response to the transfer function update prompt. A transfer function calibration module drives a calibration sequence on at least one audio output and monitors at least one audio input to determine an updated transfer function.

Abstract: An implant positioning device including a guide and holder for fasteners used in orthopaedic fixation for use in affixing a plate-like member to a bone or other part of a patient. The guide and holder includes a base adapted to align with the plate in a manner to orient fasteners with the plate for fixation. A plurality of fastener holders are on the base and adapted to releasably hold a fastener in a manner where the fastener is exposed at a proximal end for access by a fastener driver and aligned at a distal end with an aperture on the plate through which the fastener is to be driven.

Abstract: Systems and methods to cancel noise in a vehicle are disclosed. A first speaker is positioned forward of a steering wheel of a vehicle. The first speaker generates a first signal configured to acoustically cancel noise produced by operation of the vehicle. A second speaker is positioned forward of the steering wheel. The second speaker generates a second signal to acoustically cancel the noise produced by the operation of the vehicle. The first and the second speakers are capable of generating the first and the second signals independently of one another.

Abstract: A vehicle system is provided that includes a sound augmentation system with a sound augmentation generator that produces an augmented audio output to drive at least one audio output based on a transfer function. The vehicle system also includes a sound augmentation system health monitor that determines a current performance level of the sound augmentation system based on at least one audio input and a feedback of the augmented audio output, and triggers a transfer function update prompt based on a difference between the current performance level and an expected performance level being at a threshold level. A user interface outputs the transfer function update prompt and receives a transfer function calibration request in response to the transfer function update prompt. A transfer function calibration module drives a calibration sequence on at least one audio output and monitors at least one audio input to determine an updated transfer function.

Abstract: A resettable drive assembly for a drug delivery device (1) is provided. The drive assembly comprises a drive unit (3) for driving a piston rod (5) in a dispense operation of the device (1). The drive unit (3) comprises a first drive member (35), a second drive member (37) and locking means preventing a relative rotational movement of the first (35) and the second drive member (37) during a dispense operation and allowing a relative rotational movement for enabling a resetting of the device (1). Moreover, a drug delivery device (1) comprising a resettable drive assembly is provided.

Abstract: The present disclosure relates to devices that aid a user in ceasing bruxism. The devices may be placed between a user's teeth, such as during sleep, and alert the user when the user clenches his/her teeth. In an aspect, a device includes a housing containing a battery power source, a vibration device, and an electrical contact mechanism having a movable element which closes a circuit to actuate the vibration device. A disk-shaped portion adapted to be emplaced in a person's mouth between a cheek and adjacent teeth is disposed around the housing. A resilient bite portion extends from the housing and is adapted to be emplaced between upper and lower teeth. A compressible element is disposed in the bite portion and causes the movable element of the electrical contact to close to actuate the vibration device in response to compression of the bite portion.

Abstract: Various embodiments of the present technology provide a sweetener composition comprising stevia glycosides that may be stably soluble in an aqueous solution, and methods for their manufacture. In various embodiments, the sweetener composition may comprise at least one stevia glycoside and a natural emulsifier. The natural emulsifier of the sweetener composition may enhance the aqueous solubility of the stevia glycoside to increase the concentration of dissolved stevia glycoside relative to its inherent aqueous solubility. The sweetener composition may be stably soluble upon formulation into any edible sweetened substances.

Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.

Abstract: An orthopaedic fixation system for closing a resection of a body part, including a plurality of anchors located on either side of a resection which separates a body part into adjacent portions, such that there are a set of first anchors on one side of the resection and a second set of anchors on the other side of the resection. A first cable member is wound around and between the first and second sets of anchors, with the cable member extending generally orthogonally across the resection between at least certain pairs of the first and second anchors, with one of the pairs of anchors comprising a node.

Abstract: An implantable fixation device for rejoining opposed portions of a separated bone. The device including two corresponding plates that are configured to be aligned and coupled to a bone, such as a sternum, pre-resection of the bone or prior to cutting/separating the bone. The placement of the corresponding plates provides a gap between the edges of the plates that face one another allowing for and guiding a cutting tool for separating the bone. After the bone has been cut and the desired surgical procedure performed, the plates also assist in realigning and fixation of the bone portions. At least one plate includes a ratchet mechanism that is configured to tighten a locking element and draw the two plates together and into alignment with one another.

Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.

Abstract: A manifold for a torque converter assembly is disclosed. The manifold may have a base portion configured to be fixedly connected to a frame of a mobile machine. The base portion may have a first face, a second face, and an outer radial surface located between the first face and the second face. The manifold may also have a sleeve portion extending axially away from the second face of the base portion. The sleeve portion may have an outer radial surface. The base portion may further have a first passageway configured to receive hydraulic fluid. The first passageway may have an inlet in the outer radial surface of the base portion and an outlet in the outer radial surface of the sleeve portion. The manifold may also have a second passageway configured to receive hydraulic fluid. The second passageway may have an inlet in the first face and an outlet in the second face.

Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.