Patents by Inventor James Phan
James Phan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11945785Abstract: Disclosed herein are heterocyclic compounds, for example, according to the following formula and analogs thereof: that inhibit the activity of FLT3. Also described are specific covalent inhibitors of FLT3. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the FLT3 inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of proliferative diseases or conditions, including hematological malignancies and other diseases or conditions dependent on FLT3 activity.Type: GrantFiled: December 29, 2022Date of Patent: April 2, 2024Assignee: Biomea Fusion, Inc.Inventors: David Sperandio, Xiaodong Wang, Thorsten A. Kirschberg, James T. Palmer, Thomas Butler, Solomon B. Ungashe, Neil Howard Squires, Nan-Horng Lin, Ravindra B. Upasani, Amna Trinity-Turjuman Adam, Yongli Su, Thu Phan
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Patent number: 11833069Abstract: A stent coupler for use with a medical device delivery system is disclosed. A stent delivery system includes a core member having a distal segment and a coupler positioned about the core member distal segment. The coupler is rotatably coupled to the core member and includes a rigid plate having a first end surface, a second end surface, and a side surface extending between the first and second end surfaces, the side surface comprising one or more projections separated by recesses. The delivery system further includes a stent extending along the core member distal segment such that an inner surface of the stent is engaged by the one or more projections of the engagement member.Type: GrantFiled: February 1, 2021Date of Patent: December 5, 2023Assignee: COVIDIEN LPInventors: Ashok Nageswaran, Cong Dang, Aaron Barrett, James Phan
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Patent number: 11766998Abstract: A vehicle attachment for guiding a vehicle includes a magnetic tape sensor, at least one sensor, a controller, at least one coupling device for attachment to the vehicle, and a vehicle interface system. The magnetic tape sensor is configured to detect a path. The at least one sensor can detect whether there are any obstructions along the path. The controller is configured to steer the vehicle along the predefined path and to adjust the speed of the vehicle to avoid coming in contact with any obstructions. The vehicle interface system is configured to communicatively couple the controller to at least one electronic control unit of the vehicle.Type: GrantFiled: August 2, 2019Date of Patent: September 26, 2023Assignees: VOLKSWAGEN AKTIENGESELLSCHAFT, PORSCHE AGInventors: Joerg Christian Wolf, Elnaz Vahedforough, James Phan Bui, Bryan Grant, Martin Fest, Nikhil George
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Publication number: 20210154033Abstract: A stent coupler for use with a medical device delivery system is disclosed. A stent delivery system includes a core member having a distal segment and a coupler positioned about the core member distal segment. The coupler is rotatably coupled to the core member and includes a rigid plate having a first end surface, a second end surface, and a side surface extending between the first and second end surfaces, the side surface comprising one or more projections separated by recesses. The delivery system further includes a stent extending along the core member distal segment such that an inner surface of the stent is engaged by the one or more projections of the engagement member.Type: ApplicationFiled: February 1, 2021Publication date: May 27, 2021Inventors: Ashok Nageswaran, Cong Dang, Aaron Barrett, James Phan
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Patent number: 10945867Abstract: A stent coupler for use with a medical device delivery system is disclosed. A stent delivery system includes a core member having a distal segment and a coupler positioned about the core member distal segment. the coupler is rotatably coupled to the core member and includes a rigid plate having a first end surface, a second end surface, and a side surface extending between the first and second end surfaces, the side surface comprising one or more projections separated by recesses. The delivery system further includes a stent extending along the core member distal segment such that an inner surface of the stent is engaged by the one or more projections of the engagement member.Type: GrantFiled: July 1, 2019Date of Patent: March 16, 2021Assignee: COVIDIEN LPInventors: Ashok Nageswaran, Cong Dang, Aaron Barrett, James Phan
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Publication number: 20210031734Abstract: A vehicle attachment for guiding a vehicle includes a magnetic tape sensor, at least one sensor, a controller, at least one coupling device for attachment to the vehicle, and a vehicle interface system. The magnetic tape sensor is configured to detect a path. The at least one sensor can detect whether there are any obstructions along the path. The controller is configured to steer the vehicle along the predefined path and to adjust the speed of the vehicle to avoid coming in contact with any obstructions. The vehicle interface system is configured to communicatively couple the controller to at least one electronic control unit of the vehicle.Type: ApplicationFiled: August 2, 2019Publication date: February 4, 2021Inventors: Joerg Christian WOLF, Elnaz VAHEDFOROUGH, James Phan BUI, Bryan GRANT, Martin FEST, Nikhil GEORGE
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Publication number: 20200405658Abstract: A two-part topical composition includes a first composition including a S-nitrosothiol nitric oxide donor and a carrier, and a second composition including zinc oxide. The second composition is to be mixed with the first composition. The zinc oxide reacts with the S-nitrosothiol nitric oxide donor at a temperature ranging from about 20° C. to about 40° C. to enhance a rate of release of nitric oxide from a mixture of the first composition and the second composition.Type: ApplicationFiled: February 28, 2019Publication date: December 31, 2020Inventors: Joshua C. Doverspike, James Phan, Jianfeng Wu, Chuanwu Xi, Yu Qin, Mark E. Meyerhoff, Yang Zhou
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Publication number: 20190336312Abstract: A stent coupler for use with a medical device delivery system is disclosed. A stent delivery system includes a core member having a distal segment and a coupler positioned about the core member distal segment. the coupler is rotatably coupled to the core member and includes a rigid plate having a first end surface, a second end surface, and a side surface extending between the first and second end surfaces, the side surface comprising one or more projections separated by recesses. The delivery system further includes a stent extending along the core member distal segment such that an inner surface of the stent is engaged by the one or more projections of the engagement member.Type: ApplicationFiled: July 1, 2019Publication date: November 7, 2019Inventors: Ashok Nageswaran, Cong Dang, Aaron Barrett, James Phan
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Patent number: 10376396Abstract: A stent coupler for use with a medical device delivery system is disclosed. A stent delivery system includes a core member having a distal segment and a coupler positioned about the core member distal segment. the coupler is rotatably coupled to the core member and includes a rigid plate having a first end surface, a second end surface, and a side surface extending between the first and second end surfaces, the side surface comprising one or more projections separated by recesses. The delivery system further includes a stent extending along the core member distal segment such that an inner surface of the stent is engaged by the one or more projections of the engagement member.Type: GrantFiled: January 19, 2017Date of Patent: August 13, 2019Assignee: Covidien LPInventors: Ashok Nageswaran, Cong Dang, Aaron Barrett, James Phan
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Publication number: 20180200092Abstract: A stent coupler for use with a medical device delivery system is disclosed. A stent delivery system includes a core member having a distal segment and a coupler positioned about the core member distal segment. the coupler is rotatably coupled to the core member and includes a rigid plate having a first end surface, a second end surface, and a side surface extending between the first and second end surfaces, the side surface comprising one or more projections separated by recesses. The delivery system further includes a stent extending along the core member distal segment such that an inner surface of the stent is engaged by the one or more projections of the engagement member.Type: ApplicationFiled: January 19, 2017Publication date: July 19, 2018Inventors: Ashok Nageswaran, Cong Dang, Aaron Barrett, James Phan