Abstract: Ophthalmic implants such as sulcus implants which can include one or more drug delivery devices. Further provided herein are methods of using the drug delivery ophthalmic devices described herein for implantation into a subject's eye, e.g., into an eye's ciliary sulcus or capsular bag.

Abstract: An ophthalmic implant including an intraocular lens (IOL) and at least one drug delivery device. The IOL including an anterior side, a posterior side, a lens, and at least one haptic extending outwardly from the lens and including a first haptic extending from the lens at a first optic-haptic junction. The at least one drug delivery device including a first drug delivery device including a pad and a fixation portion extending from the pad. The pad including at least one therapeutic agent contained therein, an anterior surface, a posterior surface, and a sidewall extending around the pad and between the anterior surface and the posterior surface. The drug delivery device configured for attachment to the IOL via the fixation portion. In an assembled state of the implant, the first drug delivery device is attached to the IOL and the pad overlays the first optic-haptic junction.

Abstract: An ophthalmic implant including an IOL with haptics, and drug delivery devices secured to the haptics. The posterior-most extent of the drug delivery device is located anterior to the posterior edge or PCE barrier edge, of the IOL. In other configurations, the drug delivery devices are provided with PCO barrier edges.

Abstract: This disclosure provides ophthalmic implants such as sulcus implants which can comprise one or more drug delivery devices. Further provided herein are methods of using the drug delivery ophthalmic devices described herein for implantation into a subject's eye, e.g., into an eye's ciliary sulcus or capsular bag.

Abstract: An ophthalmic implant including an intraocular lens (IOL) and at least one drug delivery device. The IOL including an anterior side, a posterior side, a lens, and at least one haptic extending outwardly from the lens and including a first haptic extending from the lens at a first optic-haptic junction. The at least one drug delivery device including a first drug delivery device including a pad and a fixation portion extending from the pad. The pad including at least one therapeutic agent contained therein, an anterior surface, a posterior surface, and a sidewall extending around the pad and between the anterior surface and the posterior surface. The drug delivery device configured for attachment to the IOL via the fixation portion. In an assembled state of the implant, the first drug delivery device is attached to the IOL and the pad overlays the first optic-haptic junction.

Abstract: An ophthalmic implant including an IOL with haptics, and drug delivery devices secured to the haptics. The posterior-most extent of the drug delivery device is located anterior to the posterior edge or PCE barrier edge, of the IOL. In other configurations, the drug delivery devices are provided with PCO barrier edges.

Abstract: An ophthalmic implant configured for peri-operative, intra-operative, or post-operative assembly and disassembly. Drug delivery devices may be implanted with an intraocular lens, and later removed and replaced with new drug delivery devices.

Abstract: An ophthalmic implant including an IOL with haptics, and drug delivery devices secured to the haptics. The posterior-most extent of the drug delivery device is located anterior to the posterior edge or PCE barrier edge, of the IOL. In other configurations, the drug delivery devices are provided with PCO barrier edges.

Abstract: This disclosure provides ophthalmic implants such as sulcus implants which can comprise one or more drug delivery devices. Further provided herein are methods of using the drug delivery ophthalmic devices described herein for implantation into a subject's eye, e.g., into an eye's ciliary sulcus or capsular bag.

Abstract: An ophthalmic implant configured for peri-operative, intra-operative, or post-operative assembly and disassembly. Drug delivery devices may be implanted with an intraocular lens, and later removed and replaced with new drug delivery devices.

Abstract: An ophthalmic implant configured for peri-operative, intra-operative, or post-operative assembly and disassembly. Drug delivery devices may be implanted with an intraocular lens, and later removed and replaced with new drug delivery devices.

Abstract: An ophthalmic implant including an IOL with haptics, and drug delivery devices secured to the haptics. The posterior-most extent of the drug delivery device is located anterior to the posterior edge or PCE barrier edge, of the IOL. In other configurations, the drug delivery devices are provided with PCO barrier edges.

Abstract: An ophthalmic implant including an IOL with haptics, and drug delivery devices secured to the haptics. The posterior-most extent of the drug delivery device is located anterior to the posterior edge or PCE barrier edge, of the IOL. In other configurations, the drug delivery devices are provided with PCO barrier edges.

Abstract: An ophthalmic implant configured for peri-operative, intra-operative, or post-operative assembly and disassembly. Drug delivery devices may be implanted with an intraocular lens, and later removed and replaced with new drug delivery devices.

Abstract: A microkeratome cutting head includes a head structure, an applanation plate, and a stromal plate. The head structure may include a blade cavity for receiving a blade and a blade opening through which the blade extends. The blade is configured for creating a corneal flap at a corneal flap thickness. The applanation plate is disposed at an elevation above the stromal plate plane. The elevation difference is approximately equal to the corneal flap thickness. An artificial anterior chamber (AAC) system is used to hold the donor eye for interfacing with the microkeratome. The AAC system includes an optional pressure valve and pressure gauge in a closed loop system for the user or surgeon to control line pressure applied to the donor eye during the procedure.

Abstract: A microkeratome cutting head includes a head structure, an applanation plate, and a stromal plate. The head structure may include a blade cavity for receiving a blade and a blade opening through which the blade extends. The blade is configured for creating a corneal flap at a corneal flap thickness. The applanation plate is disposed at an elevation above the stromal plate plane. The elevation difference is approximately equal to the corneal flap thickness. An artificial anterior chamber (AAC) system is used to hold the donor eye for interfacing with the microkeratome. The AAC system includes an optional pressure valve and pressure gauge in a closed loop system for the user or surgeon to control line pressure applied to the donor eye during the procedure.

Abstract: A microkeratome that includes a latch assembly that couples a head to a hand piece. The latch assembly allows the head to be readily detached from the hand piece and sterilized. There is no need to also sterilize the hand piece. The microkeratome also has a ring assembly that is coupled to the head and the hand piece. The ring assembly may include a fastener that can be unfastened to allow the hand piece and head to be detached from the ring, even while the ring assembly is fixed to a cornea. The hand piece includes a motor that moves the blade across the ring. The microkeratome may have an aspiration connector with a collar that limits the travel of the blade the and thickness of a resulting lamella flap. The aspiration connector can be replaced with a collar of a different diameter to produce a flap with a different thickness.

Abstract: A microkeratome cutting head includes a head structure, an applanation plate, and a stromal plate. The head structure may include a blade cavity for receiving a blade and a blade opening through which the blade extends. The blade is configured for creating a corneal flap at a corneal flap thickness. The applanation plate is disposed at an elevation above the stromal plate plane. The elevation difference is approximately equal to the corneal flap thickness.