Abstract: A memory includes byte aligned column redundancy capabilities for use in repairing the memory when a defective column is present. The memory array includes a repair/redundant column for use in repairing the memory when another column of the memory array is defective. The memory also has a redundant write multiplexer to select, when a defective column is present in the memory array, an input data bit to be written to the redundant column. A first input of the redundant write multiplexer may be coupled to receive either the LSB or the MSB of write data associated with the first column group and a second input of the redundant write multiplexer may be coupled to receive either the LSB or the MSB of write data associated with the second column group.

Abstract: A memory includes byte aligned column redundancy capabilities for use in repairing the memory when a defective column is present. The memory array includes a repair/redundant column for use in repairing the memory when another column of the memory array is defective. The memory also has a redundant write multiplexer to select, when a defective column is present in the memory array, an input data bit to be written to the redundant column. A first input of the redundant write multiplexer may be coupled to receive either the LSB or the MSB of write data associated with the first column group and a second input of the redundant write multiplexer may be coupled to receive either the LSB or the MSB of write data associated with the second column group.

Abstract: A memory includes byte aligned column redundancy capabilities for use in repairing the memory when a defective column is present. The memory array includes a repair/redundant column for use in repairing the memory when another column of the memory array is defective. The memory also has a redundant write multiplexer to select, when a defective column is present in the memory array, an input data bit to be written to the redundant column. A first input of the redundant write multiplexer may be coupled to receive either the LSB or the MSB of write data associated with the first column group and a second input of the redundant write multiplexer may be coupled to receive either the LSB or the MSB of write data associated with the second column group.

Abstract: A reaction block assembly of reaction vessels for conducting chemical reactions under pressure. The assembly includes a heat conductive reactive block having reaction vessel receiving openings formed in the block. A heat exchanger is mounted in heat transfer engagement with some of the exterior walls of the reaction block. The heat exchangers can operate in different modes, to provide a heat differential across the reaction block. A reaction vessel is positioned in each reaction vessel receiving opening in the block. A cap is attached to each reaction vessel and a cannula opening is formed in each cap. A cannula passage is connected at one end to a cannula opening in each cap and it has a septum at the other end. A valve controls each cannula passage. An operating mechanism is provided for opening and closing each cannula passage controlling valve. The reaction block assembly may be used to determine when the reaction of a solution in a reaction vessel is completed.

Abstract: An array of reaction assemblies for heating and cooling a plurality of reaction vessels. Each reaction vessel assembly including a heat conductive reaction block having an exterior wall and a reaction vessel receiving cavity formed in the block inwardly of the exterior wall. A thermoelectric module is mounted in heat transfer engagement with the exterior wall of the heat conductive reaction block. A fluid heat exchange element is mounted in heat transfer engagement with the thermoelectric module. The thermoelectric module has its junctions to selectively remove heat from the exterior wall of the reaction block or to supply heat to this exterior wall. Each thermoelectric module has thermoelectric junctions cascaded for increased heating and cooling range and a plurality of these junctions to increase capacity.

Abstract: A method and an apparatus for multiple, simultaneous synthesis of compounds. The apparatus includes a reaction block having a heating layer, a cooling layer, each of which may perform both functions, and a collection sump. A plurality of reaction tubes are supported in the reaction block in a matrix. Each reaction tube has a top outlet, a bottom outlet and a filter above the bottom outlet. Spool valves are located to control the bottom outlets of the reaction tubes. Obturators are provided to close the top outlets of the reaction tubes and to provide venting for the reaction tubes. The collection sump alternately may be equipped with individual collection tubes for each reaction tube. Each reaction tube is formed with a restrictive waist and protrusions arranged in a pattern between the waist and its bottom outlet to improve the mixing of the resinous solid supports by creating turbulence.

Abstract: An apparatus for multiple, simultaneous synthesis of compounds. The apparatus includes a reaction block having a heating layer, a cooling layer, each of which may perform both functions, and a collection sump. A plurality of reaction tubes are supported in the reaction block in a matrix. Each reaction tube has a top outlet, a bottom outlet and a filter above the bottom outlet. Spool valves are located to control the bottom outlets of the reaction tubes. Obturators are provided to close the top outlets of the reaction tubes and to provide venting for the reaction tubes. The collection sump alternately may be equipped with individual collection tubes for each reaction tube. Each reaction tube is formed with a restrictive waist and protrusions arranged in a pattern between the waist and its bottom outlet to improve the mixing of the resinous solid supports by creating turbulence. The restrictive waist limits the height of the vortex of solution during mixing and reaction to facilitate heating and refluxing.

Abstract: A method and device for the simultaneous production of chemical compounds in an array which is capable of providing a very broad range of reaction environments including reaction temperatures of -40.degree. C. to 150.degree. C., reflux condensation, and a selective gas environment. The invention also allows the addition of several reagents during the course of the production process. The device is comprised of a number of different block sections which are fastened together to provide the required reaction environment.

Abstract: A method and device for detecting an antigenic material in which the device comprises a test utensil having an indentation in which two reagent spots are placed, the first body being a dyed substrate having a coating of an antibody or antibody-like material thereon and the second of the two reagent spots comprising a dyed test-inert material or a dyed substrate with a coating of a normal animal serum, the dye employed in the second reagent spot having a different color than that employed in the first spot. When a liquid test sample is added to the indentation, the dyed substrate particles or components are suspended or solubilized, and the resulting suspension gives the appearance of a third color. A positive agglutination test is indicated by the formation of at least one spot having the color of the first dyed substrate against a background having the color of the second dyed substrate.