Abstract: The present invention relates to a method and reagents for determining the presence of or the amount of an analyte in a sample.

Abstract: A cartridge, analyzer for use therewith, and system including the cartridge and analyzer. The cartridge is configured to receive a biological fluid to be analyzed and includes a plate defining a main channel, a hemolysis chamber, and an oximetry chamber consecutively interconnected with one another. The analyzer is configured to perform analysis of sample disposed within the main channel, hemolyze sample disposed within the hemolysis chamber, and perform oximetry on sample disposed within the oximetry chamber. The cartridge and analyzer may further include alignment and clamping structures for maintain the cartridge in fixed position and alignment during testing or may further include cooperating features for moving the cartridge relative to the analyzer into a testing position or between various different testing positions.

Abstract: A method for making an optical fiber bundle which, in one aspect, includes bending each of a plurality of optical fibers to form a bend therein and then suspending the fibers over a suspension member; holding the fibers taut under tension; applying potting material to the fiber bends and curing it; and removing the fibers from the suspension member.

Abstract: Apparatus are disclosed for introducing thick material into a small cavity, the apparatus in one aspect including a piston/cylinder device insertable into a block bore of a containment block, the block bore having the thick material therein for transfer to the piston bore, the piston then movable to expel the material from the piston bore into the cavity; in certain aspects the cavity of microscopic size and in other aspects thick material being a thixotropic chemical indicating material and the cavity extending through a fiber optic in a biosensor;

Abstract: Methods for making optical fiber sensor probes for measuring or monitoring parameters of fluids, including but not limited to measuring blood gas concentrations and pH either in a vessel in vitro or in a human artery. Such probes, in one aspect, have one or more optical fibers with one or more chambers with a chemical indicating materialtherein which changes in response to light transmitted therethrough. In one aspect such probes have a probe body including a plurality of fibers having a substantial portion of their surfaces covered with an opaque material to enhance light signal transmission therethrough. Such probes may also have a coating thereon of an anti-thrombogenic mnaterial.

Abstract: An apparatus for holding the stator of a vessel rotatable about an axis of rotation, includes a pivotable swing arm having a first end and a second end, the second end having an engagement portion for contacting the stator of a rotating vessel. A support is connected to the first end of the swing arm and has an axis spaced from and substantially parallel to the axis of rotation. The support cooperates with the swing arm to permit the swing arm to pivot toward and away from the stator. A detent finger, located in the swing arm cooperates with the stator to hold the stator against rotation when the swing arm is in a predetermined angular position, and maintains the stator in a fixed position relative to the swing arm during a centrifuge operation. Finally, a detent cam assembly resists pivotal movement of the swing arm when the swing arm is in the predetermined angular position.

Abstract: A rivet orienting and handling device is disclosed that is capable of controllably and accurately handling rivets of different size diameters. The device includes a manifold adapted to receive rivets from a remote hopper, a body adapted to transport rivets and two rivet blocks adapted to receive and position rivets for insertion into fingers. The rivet blocks are positioned by air actuated leaf springs. The springs cause the distance between the rivet block to vary to accommodate rivets having different diameters.

Abstract: Methods and apparatuses for securely aligning a plurality of optical fiber pairs, including a connection device with a body having recesses therein for a fiber guide to which are mounted a plurality of optical fibers, a removable connector to which are mounted a corresponding plurality of fibers, and a movable locking member disposed in the body and which positively holds the connector in the body so that ends of pairs of fibers are aligned and the connector is securely disposed in the body; and a sensing system with a base unit and optical fibers which employs such a connection device.

Abstract: Connector for stable interface of optical fibers, in one aspect having matable body parts with interior fiber mounts, the matable body parts securable together e.g. by one or more retention clips, snap-fit, or one or more screws; and in one aspect, a middle block or bushing bar for increased stability and convenient access to fiber ends.

Abstract: Method for making a probe with a plurality (one or more) of optical fiber sensors containing colorimetric chemical indicators in gaps in the fibers, the fibers bent to provide good light transmission qualities. Apparatus for making a probe with a plurality of such optical fiber sensors. A probe with a plurality of such optical fiber sensors. A vacuum chuck for holding the ends of such fibers.