Patents by Inventor James Robinson, III

James Robinson, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CLEAN, HIGH-YIELD PREPARATION OF S,S AND R,S AMINO ACID ISOSTERES
    Publication number: 20130116457
    Abstract: The present invention provides compounds and methods that can be used to convert the intermediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S-diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity.
    Type: Application
    Filed: June 7, 2012
    Publication date: May 9, 2013
    Applicant: Aerojet Fine Chemicals LLC
    Inventors: Aslam A. Malik, Todd E. Clement, Hasan Palandoken, James Robinson, III, Joy A. Stringer
  • Clean, high-yield preparation of S,S and R,S amino acid isosteres
    Patent number: 8163933
    Abstract: The present invention provides compounds and methods that can be used to convert the intermediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S-diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: April 24, 2012
    Assignee: Ampac Fine Chemicals LLC
    Inventors: Aslam A. Malik, Todd E. Clement, Hasan Palandoken, James Robinson, III, Joy A. Stringer
  • CLEAN, HIGH-YIELD PREPARATION OF S,S AND R,S AMINO ACID ISOSTERES
    Publication number: 20090012303
    Abstract: The present invention provides compounds and methods that can be used to convert the intermediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S-diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity.
    Type: Application
    Filed: December 14, 2007
    Publication date: January 8, 2009
    Applicant: Aerojet Fine Chemicals LLC
    Inventors: Aslam A. Malik, Todd E. Clement, Hasan Palandoken, James Robinson, III, Joy A. Stringer
  • Clean, High-yield preparation of S,S and R,S amino acid isosteres
    Patent number: 7309803
    Abstract: The present invention provides compounds and methods that can be used to convert the intermmediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S-diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity.
    Type: Grant
    Filed: March 14, 2005
    Date of Patent: December 18, 2007
    Assignee: Aerojet Fine Chemicals LLC
    Inventors: Aslam A. Malik, Todd E. Clement, Hasan Palandoken, James Robinson, III, Joy A. Stringer
  • Clean, high-yield preparation of S,S and R,S amino acid isosteres
    Patent number: 6867311
    Abstract: The present invention provides compounds and methods that can be used to convert the intermediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S-diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity.
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: March 15, 2005
    Assignee: Aerojet Fine Chemicals LLC
    Inventors: Aslam A. Malik, Todd E. Clement, Hasan Palandoken, James Robinson, III, Joy A. Stringer
  • Clean, high-yield preparation of S,S and R,S amino acid isosteres
    Patent number: 6605732
    Abstract: The present invention provides compounds and methods that can be used to convert the intermediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S-diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity.
    Type: Grant
    Filed: May 28, 1999
    Date of Patent: August 12, 2003
    Assignee: Aerojet Fine Chemicals LLC
    Inventors: Aslam A. Malik, Todd E. Clement, Hasan Palandoken, James Robinson, III, Joy A. Stringer
  • (1-azabicyclo[2.2.2]oct-3-yl) (1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amine and n-(1-azabicyclo[2.2.2]o c
    Patent number: 5576434
    Abstract: Compounds of Formula 6: ##STR1## in which R.sup.1 and R.sup.2 are each hydrogen or together form .dbd.O.
    Type: Grant
    Filed: January 24, 1996
    Date of Patent: November 19, 1996
    Inventors: James Robinson, III, John C. Rohloff, Bruce A. Kowalczyk
  • Process for preparing 2-(1-azabicyclo 2.2.2!oct-3-yl)-2,3,3A,4,5,6-hexahydro-1H-benz de!isoqui nolin-1-one
    Patent number: 5510486
    Abstract: This invention relates to a process for preparing 2-(1-azabicyclo 2.2.2!oct-3-yl)-2,3,3a,4,5,6-tetrahydro-1H-benz de!isoquin olin-1-one, particularly 2-(1-azabicyclo 2.2.2!oct-3S-yl)-2,3,3aS,4,5,6-tetrahydro-1H-benz de!isoqu inolin-1-one, and to intermediates useful in such process.
    Type: Grant
    Filed: July 26, 1994
    Date of Patent: April 23, 1996
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: James Robinson, III, John C. Rohloff, Bruce A. Kowalczyk