Abstract: The present invention provides methods for utilizing blended compositions of acetonitrile and toluene as organic wash solvents in the production of a synthetic oligonucleotide, the blended compositions producing higher synthetic oligonucleotide yields than a pure acetonitrile wash solvent. The method also provides a process for removing one or more impurities from the acetonitrile and toluene containing wash solvent received as a waste stream from the oligonucleotide synthesis process. The process includes adding at least one of an iodine reactive compound, a sulfur reactive compound and/or an acidic reactive compound to the waste stream, and fractionating the waste stream. The fractionation produces an overhead fraction and a bottom fraction where the overhead fraction includes the acetonitrile and the toluene, and the bottom fraction includes the one or more impurities.

Abstract: A technique facilitates deployment and operation of a pumping system, e.g. an electric submersible pumping system, in a borehole. A locking and sealing mechanism, e.g. a spring-loaded locking sealing mechanism, may be coupled with the pumping system and comprises an anchoring section along with a sealing section. The locking sealing mechanism may be constructed for deployment with the pumping system via a running tool. Once in position downhole, the anchoring section and the sealing section may be actuated into sealing engagement with the interior surface of a surrounding tubing. At this stage, production of a desired fluid may be accomplished by operating the pumping system.

Abstract: This disclosure describes systems, methods, and apparatus for decorating a can comprising a base, a curvilinear side surface extending in an upward direction from the base and comprising a neck and flanged portion, wherein the base and curvilinear side surface are formed using a metallic material, and at least one layer each of a first ink and a first overvarnish applied on at least a portion of the curvilinear side surface. The method further comprises surface treating the curvilinear side surface to increase a surface energy of the first overvarnish, applying one or more layers of an obscurant coating to the portion of the curvilinear side surface, wherein the portion may or may not include the neck and flanged portion, applying one or more layers of a second overvarnish and/or second ink to the portion of the curvilinear surface of the can, and curing the can.

Abstract: A technique facilitates use of a submersible pumping system deployed downhole in a borehole. A docking assembly comprises a docking station which has at least one electrical wet connector and is coupled to a receiving tubular. An electrical power cable is coupled to the docking station to enable electrical power to be provided to the at least one electrical wet connector. The docking assembly is deployed downhole to a desired location in the borehole to enable coupling with the submersible pumping system. The submersible pumping system is simply moved downhole into the receiving tubular and into electrical engagement with the electrical wet connectors.

Abstract: A intranasal device and method for self-administration of a medicament are provided. The intranasal device includes a body, a catheter, a feedback mechanism, and a delivery system. The body has a chamber configured to store the medicament. The body defines a channel that extends from an interior of the body to an exterior of the body. The catheter is configured to be actuated to extend from the body through the channel and is in fluid communication with the chamber. A distal end of the catheter is configured for entry into a nasal passage of a patient. The feedback mechanism is configured to indicate a position of the distal end of the catheter within the nasal passage. The delivery system is configured to deliver the medicament from the chamber into the nasal passage via the catheter.

Abstract: A technique facilitates deployment and operation of a pumping system, e.g. an electric submersible pumping system, in a borehole. A locking and sealing mechanism, e.g. a spring-loaded locking sealing mechanism, may be coupled with the pumping system and comprises an anchoring section along with a sealing section. The locking sealing mechanism may be constructed for deployment with the pumping system via a running tool. Once in position downhole, the anchoring section and the sealing section may be actuated into sealing engagement with the interior surface of a surrounding tubing. At this stage, production of a desired fluid may be accomplished by operating the pumping system.

Abstract: A technique facilitates use of a submersible pumping system deployed downhole in a borehole. A docking assembly comprises a docking station which has at least one electrical wet connector and is coupled to a receiving tubular. An electrical power cable is coupled to the docking station to enable electrical power to be provided to the at least one electrical wet connector. The docking assembly is deployed downhole to a desired location in the borehole to enable coupling with the submersible pumping system. The submersible pumping system is simply moved downhole into the receiving tubular and into electrical engagement with the electrical wet connectors.

Abstract: A method of deploying a downhole tool into a wellbore includes: lowering a cable into the wellbore; after lowering the cable, engaging a mold with an outer surface of the cable; injecting sealant into the mold and into armor of the cable, thereby sealing a portion of the cable; lowering the downhole tool to a deployment depth using the cable; engaging a seal with the sealed portion of the cable; and operating the downhole tool using the cable.

Abstract: A method of inserting a downhole assembly into a live wellbore, includes: assembling a pressure control assembly (PCA) onto a production tree of the live wellbore; inserting a first deployment section of the downhole assembly into a lubricator; landing the lubricator onto the PCA; connecting the lubricator to the PCA; lowering the first deployment section into the PCA; engaging a clamp of the PCA with the first deployment section; after engaging the clamp, isolating an upper portion of the PCA from a lower portion of the PCA; and after isolating the PCA, removing the lubricator from the PCA.

Abstract: A pump for use in anal irrigation includes a control unit integrated in the pump. The control unit includes a cylindrical housing element and a valve element fitted in the housing. The valve element and the housing element are adapted for rotating with respect to each other between a position allowing the pump to pump air into a balloon, a position allowing the pump to pump air into a reservoir bag and an evacuation position. The control unit is actuated by a handle attached to the rotatable valve element. The handle extends radially out from the rotatable valve element and the cylindrical housing.

Abstract: An injector for deploying a cable into a wellbore includes a traction assembly having at least a stationary segment and a movable segment. Each segment includes: a drive sprocket; an idler sprocket; a track looped around and between the sprockets; a set of grippers fastened to and disposed along the respective track, and a frame. The frame: is connected to the stationary segment, has a coupling for connection to a pressure control assembly (PCA), and has a passage for receiving the cable. The injector further includes a motor torsionally connected to the drive sprocket of the stationary segment.

Abstract: A method of deploying a downhole tool into a wellbore includes: lowering a cable into the wellbore; after lowering the cable, engaging a mold with an outer surface of the cable; injecting sealant into the mold and into armor of the cable, thereby sealing a portion of the cable; lowering the downhole tool to a deployment depth using the cable; engaging a seal with the sealed portion of the cable; and operating the downhole tool using the cable.

Abstract: A pump for use in anal irrigation includes a control unit integrated in the pump. The control unit includes a cylindrical housing element and a valve element fitted in the housing. The valve element and the housing element are adapted for rotating with respect to each other between a position allowing the pump to pump air into a balloon, a position allowing the pump to pump air into a reservoir bag and an evacuation position. The control unit is actuated by a handle attached to the rotatable valve element. The handle extends radially out from the rotatable valve element and the cylindrical housing.

Abstract: A method of chemical vapor infiltration and deposition includes stacking a number of porous structures in a stack in a furnace. The stack has a center opening region extending through the porous structures and an outer region extending along the porous structures. A first portion of a reactant gas is introduced to the center opening region. A second portion of the reactant gas is introduced to the outer region. The first portion and the second portion are controlled proportions thereby introducing predetermined portions of the reactant gas to both the center opening region and the outer region. The change in weight of the entire furnace, including contents, is measured during the chemical vapor infiltration and deposition process. The rate of weight change is monitored.