Patents by Inventor James Schouten

James Schouten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BACTERIAL VAGINOSIS DIAGNOSTIC
    Publication number: 20210293791
    Abstract: The invention provides a sialidase enzyme activity detection kit or device comprising: (i) an indicator molecule comprising a sialylated peptide and a capture site; (ii) a capture zone comprising capture molecules; and (iii) binding molecules capable of binding to the de-sialylated derivative of the indicator molecule. Also provided are methods of using the kits or devices, as well as specific indicator molecules and specific binding molecules.
    Type: Application
    Filed: July 26, 2019
    Publication date: September 23, 2021
    Applicant: MOLOGIC LTD
    Inventors: Paul DAVIS, James SCHOUTEN
  • Detection of cleavage activity of an enzyme
    Patent number: 10866236
    Abstract: The present invention relates to detecting cleavage activity of an enzyme. The various aspects of the invention include an enzyme detection device, kit, method and use for detecting or measuring the presence in a test sample of the activity of an enzyme capable of cleaving a substrate. The invention also relates to indicator and binding molecules useful for carrying out the invention. The enzyme substrate contains a hidden binding site which is only revealed upon cleavage by the enzyme.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: December 15, 2020
    Assignee: Mologic Limited
    Inventors: Paul Davis, Gita Parekh, James Schouten
  • DETECTION OF CLEAVAGE ACTIVITY OF AN ENZYME
    Publication number: 20200378963
    Abstract: The present invention relates to detecting cleavage activity of an enzyme. The various aspects of the invention include an enzyme detection device, kit, method and use for detecting or measuring the presence in a test sample of the activity of an enzyme capable of cleaving a substrate. The invention also relates to indicator and binding molecules useful for carrying out the invention. The enzyme substrate contains a hidden binding site which is only revealed upon cleavage by the enzyme.
    Type: Application
    Filed: June 23, 2020
    Publication date: December 3, 2020
    Applicant: Mologic Limited
    Inventors: Paul Davis, Gita Parekh, James Schouten
  • Detection of Cleavage Activity Of An Enzyme
    Publication number: 20160238596
    Abstract: The present invention relates to detecting cleavage activity of an enzyme. The various aspects of the invention include an enzyme detection device, kit, method and use for detecting or measuring the presence in a test sample of the activity of an enzyme capable of cleaving a substrate. The invention also relates to indicator and binding molecules useful for carrying out the invention. The enzyme substrate contains a hidden binding site which is only revealed upon cleavage by the enzyme.
    Type: Application
    Filed: October 23, 2014
    Publication date: August 18, 2016
    Applicant: Mologic Limited
    Inventors: Paul Davis, Gita Parekh, James Schouten
  • Protease detection
    Patent number: 9376706
    Abstract: A polypeptide comprising a chromogenic amino acid. The chromogenic amino acid is flanked by at least one amino acid to the N and C termini thereof. The amine group of the chromogenic amino acid has a pKa of less than 5. The chromogenic amino acid is capable of reacting with a conjugated aldehyde. The polypeptide comprises a target sequence for a target protease which is capable of cleaving the peptide bond comprising the amino group of the chromogenic amino acid.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: June 28, 2016
    Assignee: Mologic Limited
    Inventor: James A. Schouten
  • PROTEASE DETECTION
    Publication number: 20150152471
    Abstract: A polypeptide comprising a chromogenic amino acid. The chromogenic amino acid is flanked by at least one amino acid to the N and C termini thereof. The amine group of the chromogenic amino acid has a pKa of less than 5. The chromogenic amino acid is capable of reacting with a conjugated aldehyde. The polypeptide comprises a target sequence for a target protease which is capable of cleaving the peptide bond comprising the amino group of the chromogenic amino acid.
    Type: Application
    Filed: November 25, 2014
    Publication date: June 4, 2015
    Inventor: James A. Schouten