Abstract: An integral structure is provided for chemical processing and manufacture, in which a plurality of laminae are joined together and having inlet and outlet ports connected by a three dimensionally tortuous channel. Chemicals are introduced through the inlet ports and processed along the channel, with desirable product withdrawn through the outlet ports. The laminae are of materials selected to be compatible with the chemical process, from the group consisting of elements of groups III, IV or V of the Periodic Table, ceramics, glasses, polymers, composites and metals. Processes of manufacture of the apparatus and processes utilizing the apparatus are also disclosed herein.