Patents by Inventor James W. Brodack

James W. Brodack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radiopharmaceutical formulations having non-stannous reductants
    Patent number: 5662882
    Abstract: The present invention relates to novel radiopharmaceutical imaging agents having non-stannous reductants. The present invention further relates to kits for forming radiopharmaceutical imaging agents, such kits including non-stannous reducing agents.
    Type: Grant
    Filed: March 23, 1995
    Date of Patent: September 2, 1997
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: James W. Brodack, Mark A. DeRosch, Edward A. Deutsch, Mary Marmion Dyszlewski
  • Radionuclide labelled particles useful for radiation synovectomy
    Patent number: 5560901
    Abstract: The present invention provides radiation synovectomy compositions for treating inflamed synovium containing a radionuclide complex bound to a hydroxyapatite-like matrix as the radiolabelled synovectomy agent in a sufficient amount to provide satisfactory synovectomy of the inflamed synovium together with a pharmaceutically acceptable vehicle, the radionuclide being a beta emitter that will substantially ablate the inflamed synovium, but not significantly damage underlying articular cartilage, the radionuclide complex being substantially kinetically stable, and if said radionuclide or radionuclide complex leaks from said joint it will be excreted from the body, the agent having a particle size such that there is essentially little or no leakage of the radionuclide complex from the joint after administration.
    Type: Grant
    Filed: March 21, 1994
    Date of Patent: October 1, 1996
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: James W. Brodack, Edward A. Deutsch, Karen F. Deutsch, Dennis L. Nosco
  • Stabilizers to prevent autoradiolysis of radiolabeled peptides and proteins
    Patent number: 5384113
    Abstract: Gentisic acid and its derivatives substantially inhibit peptide autoradiolysis. Gentisic acid or its derivatives may also be used in combination with other stabilizers such as inositol and ascorbic acid to inhibit autoradiolysis of radiolabeled peptides.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: January 24, 1995
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: Edward A. Deutsch, Wilhelmus T. Goedemans, Martinus T. Maria de Jong, Kathleen M. Miller, James W. Brodack
  • Radionuclide labelled particles useful for radiation synovectomy
    Patent number: 5320824
    Abstract: The present invention provides radiation synovectomy compositions for treating inflamed synovium containing a radionuclide complex bound to a substantially insoluble particle as the radiolabelled synovectomy agent in a sufficient amount of provide satisfactory synovectomy of the inflamed synovium together with a pharmaceutically acceptable vehicle, the radionuclide being a beta emitter that will substantially ablate the inflamed synovium, but not significantly damage underlying articular cartilage, the radionuclide complex being substantially kinetically stable, and if said radionuclide or radionuclide complex leaks from said joint it will be excreted from the body, the agent having a particle size such that there is essentially little or no leakage of the radionuclide complex from the joint after administration.
    Type: Grant
    Filed: April 16, 1993
    Date of Patent: June 14, 1994
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: James W. Brodack, Edward A. Deutsch, Karen F. Deutsch, Dennis L. Nosco