Patents by Inventor James W. Hodges

James W. Hodges has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220040160
    Abstract: A method of reducing cancer cell growth, a method of increasing sensitivity of cancer cells to CTL mediated killing, and a method of increasing sensitivity of cancer cells to NK mediated killing are provided. The methods comprise treating cancer cells with a combination of a HDAC inhibitor and immunotherapy.
    Type: Application
    Filed: August 16, 2021
    Publication date: February 10, 2022
    Applicant: The United States of America,as represented by the Secretary,Department of Health and Human Services
    Inventors: James W. Hodge, Sofia R. Gameiro
  • Publication number: 20200140567
    Abstract: The invention is directed to methods of reducing growth of prostate cancer cells and breast cancer cells, which comprises treating such cancer cells with a combination of androgen or endocrine deprivation therapy (e.g., enzalutamide, abiraterone, and tamoxifen) and immunotherapy.
    Type: Application
    Filed: November 18, 2019
    Publication date: May 7, 2020
    Applicant: The United States of America,as represented by the Secretary,Department of Health and Human Services
    Inventors: Jeffrey Schlom, James W. Hodge
  • Publication number: 20190183870
    Abstract: A method of reducing cancer cell growth, a method of increasing sensitivity of cancer cells to CTL mediated killing, and a method of increasing sensitivity of cancer cells to NK mediated killing are provided. The methods comprise treating cancer cells with a combination of a HDAC inhibitor and immunotherapy.
    Type: Application
    Filed: January 4, 2017
    Publication date: June 20, 2019
    Applicant: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: James W. Hodge, Sofia R. Gameiro
  • Publication number: 20170306042
    Abstract: The invention is directed to methods of reducing growth of prostate cancer cells and breast cancer cells, which comprises treating such cancer cells with a combination of androgen or endocrine deprivation therapy (e.g., enzalutamide, abiraterone, and tamoxifen) and immunotherapy.
    Type: Application
    Filed: August 28, 2015
    Publication date: October 26, 2017
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventors: Jeffrey Schlom, James W. Hodge
  • Patent number: 9494236
    Abstract: A gasket is provided with two dissimilar materials. The two different materials are used to provide different sealing characteristics. In one embodiment, the different sealing materials join to create the same or a similar profile to the profile of the individual materials. In another embodiment, the different sealing materials have the same profile but have joining portions that are complementary to one another where the two materials are joined to one another.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: November 15, 2016
    Assignee: Dana Automotive Systems Group, LLC
    Inventors: Christopher M. Cook, Kelly D. Puckett, Dakota W. Foster, Jason D. Wimberley, Justin R. Knott, James W. Hodges
  • Publication number: 20160131258
    Abstract: A gasket is provided with two dissimilar materials. The two different materials are used to provide different sealing characteristics. In one embodiment, the different sealing materials join to create the same or a similar profile to the profile of the individual materials.
    Type: Application
    Filed: November 6, 2014
    Publication date: May 12, 2016
    Inventors: Christopher M. Cook, Kelly D. Puckett, Dakota W. Foster, Jason D. Wimberley, Justin R. Knott, James W. Hodges
  • Patent number: 8933041
    Abstract: The present invention is directed to a system for treating individuals at risk of or suffering from breast cancer. The system comprises administering to the individual a recombinant poxvirus, where the poxvirus contains in a foreign nucleic acid encoding at least one breast cancer antigen.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: January 13, 2015
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Dennis L. Panicali, Gail P. Mazzara, Linda R. Gritz, Jeffrey Schlom, Kwong-Yok Tsang, James W. Hodge
  • Patent number: 8901093
    Abstract: The present invention is directed to a system for treating individuals at risk of developing or suffering from pancreatic cancer. The system comprises administering to the individual a recombinant poxvirus, where the poxvirus contains a foreign nucleic acid encoding at least one pancreatic tumor associated antigen (PTAA).
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: December 2, 2014
    Assignee: The United States of America, as represented by the Secretary of the Department of Health and Human Services
    Inventors: Dennis L. Panicali, Gail P. Mazzara, Linda R. Gritz, Jeffrey Schlom, Kwong-Yok Tsang, James W. Hodge
  • Patent number: 7662395
    Abstract: The present invention is a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immunostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provide using the composition.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: February 16, 2010
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jeffrey Schlom, Judith Kantor, James W. Hodge
  • Publication number: 20080279887
    Abstract: The present invention is a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immunostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provide using the composition.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 13, 2008
    Applicant: The Government of the United States of America, as Represented by the Secretary, Department of Healt
    Inventors: Jeffrey Schlom, Judith Kantor, James W. Hodge
  • Publication number: 20080166367
    Abstract: The present invention is directed to a system for treating individuals at risk of developing or suffering from pancreatic cancer. The system comprises administering to the individual a recombinant poxvirus, where the poxvirus contains a foreign nucleic acid encoding at least one pancreatic tumor associated antigen (PTAA).
    Type: Application
    Filed: November 12, 2004
    Publication date: July 10, 2008
    Inventors: Dennis L. Panicali, Gail P. Mazzara, Linda R. Gritz, Jeffrey Schlom, Kwong-Yok Tsang, James W. Hodge
  • Patent number: 7368116
    Abstract: The present invention is a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immunostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provide using the composition.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: May 6, 2008
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jeffrey Schlom, Judith Kantor, James W. Hodge
  • Patent number: 6893869
    Abstract: The present invention is a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immunostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provide using the composition.
    Type: Grant
    Filed: January 14, 2003
    Date of Patent: May 17, 2005
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Jeffrey Schlom, Judith Kantor, James W. Hodge
  • Patent number: 6548068
    Abstract: The present invention is a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immunostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provide using the composition.
    Type: Grant
    Filed: January 7, 2000
    Date of Patent: April 15, 2003
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Jeffrey Schlom, Judith Kantor, James W. Hodge
  • Patent number: 6045802
    Abstract: The present invention is a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immunostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provide using the composition.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 4, 2000
    Assignee: The United States of America as represented by the Secretary of the Department Of Health and Human Services
    Inventors: Jeffrey Schlom, Judith Kantor, James W. Hodge
  • Patent number: 5417272
    Abstract: A pivotal and extendable bathing door unit is disclosed wherein a first panel is pivotally connected to a supporting wall, and a second panel is extendably connected to the first panel, so that the door can operate to enclose without an overhead track. There are roller tracks and rollers cross-linked to each other while permitting lateral relative movement therebetween. In one form, cam members are associated with the pivotal connection of the first panel to provide a lifting action between bistable positions, and a magnetic member is connected to a handle on the second panel for attraction to a similar second panel of a second similar door unit.
    Type: Grant
    Filed: July 2, 1993
    Date of Patent: May 23, 1995
    Assignee: Sterling Plumbing Group, Inc.
    Inventors: James L. Marlowe, Ronald M. Wise, Larry D. Bruce, James W. Hodges
  • Patent number: 4453346
    Abstract: An adjustable wall jamb assembly for a shower door comprising a fixed wall jamb member adapted to be affixed to a wall, an adjustable block assembly comprising a block adapted to be affixed to the fixed wall jamb and having a threaded opening, and an adjustment screw having an external thread complementary with that of the adjustment block, the adjustment screw having an axial aperture and engaging means at one end for being engaged and rotated within the adjustment block, an adjustable jamb member adapted to slide over the fixed jamb member and to engage the end of the adjustment screw, and a screw disposed through an aperture in the adjustable jamb member, extending through the axial opening of the adjustable screw and being adapted to enter the wall on which the fixed jamb member is mounted.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: June 12, 1984
    Assignee: United States Gypsum Company
    Inventors: David W. Powell, James W. Hodges