Patents by Inventor James W. Winkelman

James W. Winkelman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11911090
    Abstract: Methods and systems are disclosed for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to electrical energy. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: February 27, 2024
    Assignee: Clear Intradermal Technologies, Inc.
    Inventors: James W. Winkelman, Martin E. Schmieg
  • Publication number: 20230165622
    Abstract: Methods and systems are disclosed for removing a tattoo from a subject's skin by application of a cold plasma that is delivered via a liquid-gas mixture. The plasma can be delivered in the form of gas bubbles, in which at least a portion of gas is in the form of a plasma.
    Type: Application
    Filed: November 7, 2022
    Publication date: June 1, 2023
    Applicant: Clear Intradermal Technologies, Inc.
    Inventors: James W. WINKELMAN, Martin E. SCHMIEG
  • Publication number: 20230000538
    Abstract: A method and system for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to a cold plasma is described herein. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.
    Type: Application
    Filed: September 9, 2022
    Publication date: January 5, 2023
    Applicant: Clear Intradermal Technologies, Inc.
    Inventors: James W. WINKELMAN, Martin E. SCHMIEG
  • Patent number: 11490947
    Abstract: Methods and systems are disclosed for removing a tattoo from a subject's skin by application of a cold plasma that is delivered via a liquid-gas mixture. The plasma can be delivered in the form of gas bubbles, in which at least a portion of gas is in the form of a plasma.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: November 8, 2022
    Assignee: Clear Intradermal Technologies, Inc.
    Inventors: James W. Winkelman, Martin E. Schmieg
  • Patent number: 11439453
    Abstract: A method and system for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to a cold plasma is described herein. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: September 13, 2022
    Assignee: Clear Intradermal Technologies, Inc.
    Inventors: James W. Winkelman, Martin E. Schmieg
  • Publication number: 20220151698
    Abstract: Methods and systems are disclosed for removing a tattoo from a subject's skin by application of radiation to a target region of a subject's tattooed dermis, mobilization of tattoo ink particles, and extraction of the tattoo ink particles from the tattooed dermis. In certain embodiments, the invention can further include induction of a plasma, e.g., a cold atmospheric plasma, at the target region to assist in the degradation, dislodgement and/or mobilization of the tattoo ink particles.
    Type: Application
    Filed: November 16, 2021
    Publication date: May 19, 2022
    Inventors: James W. WINKELMAN, Martin E. SCHMIEG
  • Patent number: 11105795
    Abstract: Methods and compositions for simulating a dermal compartment of skin are disclosed. In one aspect of the invention, methods of producing such a skin model include the steps of admixing a collagenous protein source, a blood protein source, and dermal cells in an aqueous carrier, and then allowing the resulting mixture to solidify to produce a gel. In one technique, at least a portion of the mixture, e.g., the collagenous protein source is first heated and then cooled to induce gelation. For example, the mixture can be heated to at least 50 degrees C. and then cooled to temperature below 5 degrees C. to induce gelation.
    Type: Grant
    Filed: January 8, 2019
    Date of Patent: August 31, 2021
    Assignee: ClearIt, LLC
    Inventors: James W. Winkelman, Martin E. Schmieg
  • Publication number: 20200352620
    Abstract: Methods and systems are disclosed for removing a tattoo from a subject's skin by application of a cold plasma that is delivered via a liquid-gas mixture. The plasma can be delivered in the form of gas bubbles, in which at least a portion of gas is in the form of a plasma.
    Type: Application
    Filed: July 24, 2020
    Publication date: November 12, 2020
    Inventors: James W. WINKELMAN, Martin E. SCHMIEG
  • Publication number: 20200305950
    Abstract: A method and system for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to a cold plasma is described herein. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.
    Type: Application
    Filed: June 16, 2020
    Publication date: October 1, 2020
    Inventors: James W. WINKELMAN, Martin E. SCHMIEG
  • Patent number: 10716611
    Abstract: A method and system for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to a cold plasma is described herein. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: July 21, 2020
    Assignee: ClearIt, LLC
    Inventors: James W. Winkelman, Martin E. Schmieg
  • Publication number: 20200197077
    Abstract: Methods and systems are disclosed for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to electrical energy. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 25, 2020
    Inventors: James W. WINKELMAN, Martin E. SCHMIEG
  • Publication number: 20200197078
    Abstract: Methods and systems are disclosed for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to electrical energy while activating a kinetic applicator that causes an active tip of an electrode applying the electrical energy to move within the dermis, whereby the tattoo will be degraded by the combined application of energy and tip movement. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 25, 2020
    Inventors: James W. WINKELMAN, Martin E. SCHMIEG
  • Publication number: 20200116704
    Abstract: Methods and compositions for simulating a dermal compartment of skin are disclosed. In one aspect of the invention, methods of producing such a skin model include the steps of admixing a collagenous protein source, a blood protein source, and dermal cells in an aqueous carrier, and then allowing the resulting mixture to solidify to produce a gel. In one technique, at least a portion of the mixture, e.g., the collagenous protein source is first heated and then cooled to induce gelation. For example, the mixture can be heated to at least 50 degrees C. and then cooled to temperature below 5 degrees C. to induce gelation.
    Type: Application
    Filed: January 8, 2019
    Publication date: April 16, 2020
    Inventors: James W. Winkelman, Martin E. Schmieg
  • Publication number: 20160331439
    Abstract: A method and system for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to a cold plasma is described herein. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.
    Type: Application
    Filed: May 16, 2016
    Publication date: November 17, 2016
    Inventors: James W. Winkelman, Martin E. Schmieg
  • Patent number: 9176121
    Abstract: A method of identifying the elements of a blood sample including placing an aliquot of blood on a transparent substrate such as a coverslip. The blood is allowed to stand and the cells to settle to form a layer or matrix. Inverted microscopy is used to identify the elements in the sample. Various forms of illumination may be used alone or in multiple combinations. The method improves the accuracy due to homogenous distribution of formed elements in the wet drop or aliquot, simplifies the method, lowers the cost of the test and results in a shortened analytical cycle time.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: November 3, 2015
    Assignee: Roche Diagnostics Hematology, Inc.
    Inventors: James W. Winkelman, Milenko J. Tanasijevic, David Zahniser
  • Publication number: 20080138852
    Abstract: A method of identifying the elements of a blood sample including placing an aliquot of blood on a transparent substrate such as a coverslip. The blood is allowed to stand and the cells to settle to form a layer or matrix. Inverted microscopy is used to identify the elements in the sample. Various forms of illumination may be used alone or in multiple combinations. The method improves the accuracy due to homogenous distribution of formed elements in the wet drop or aliquot, simplifies the method, lowers the cost of the test and results in a shortened analytical cycle time.
    Type: Application
    Filed: February 11, 2005
    Publication date: June 12, 2008
    Inventors: James W. Winkelman, Milenko J. Tanasijevic, David Zahniser
  • Publication number: 20030216284
    Abstract: A series of articles and techniques for controlled pharmaceutical delivery within a patient is described. An article includes at least one cavity having an interior dimension equal to a resonant mode of electromagnetic radiation to which the article is exposed. A standing wave is created within the cavity, causing a change in a diffusion characteristic of at least one component of the cavity, in turn causing release of a pharmaceutical from the cavity into an area of the body surrounding the article. Low-energy, non-destructive electromagnetic radiation, such as visible or near-infrared light, can be used.
    Type: Application
    Filed: January 6, 2003
    Publication date: November 20, 2003
    Applicant: Massachusetts Institute of Technology
    Inventors: Yoel Fink, Edwin L. Thomas, John D. Joannopoulos, James W. Winkelman
  • Publication number: 20030113930
    Abstract: A method and apparatus is disclosed for determining the erythrocyte sedimentation rate and hematocrit simultaneously with the centrifugation of whole blood. A centrifuge separates the whole blood into its erythrocytes and its fluid portion. A video camera measures the levels of whole blood, erythrocytes and the fluid portion of the blood-and records the time of the formation of an interface between the erythrocytes and fluid portion. A monitor displays the results of the recording. Also disclosed are the method steps performed.
    Type: Application
    Filed: January 13, 2003
    Publication date: June 19, 2003
    Inventors: James W. Winkelman, Milenko J. Tanasijevic, Michael Bennett
  • Patent number: 6506606
    Abstract: A method and apparatus is disclosed for determining the erythrocyte sedimentation rate and hematocrit simultaneously with the centrifugation of whole blood. A centrifuge separates the whole blood into its erythrocytes and its fluid portion. A video camera measures the levels of whole blood, erythrocytes and the fluid portion of the blood and records the time of the formation of an interface between the erythrocytes and fluid portion. A monitor displays the results of the recording. Also disclosed are the method steps performed.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 14, 2003
    Assignee: Brigham and Women's Hospital
    Inventors: James W. Winkelman, Milenko J. Tanasijevic, Michael Bennett
  • Patent number: 6398705
    Abstract: The method of rapidly separating plasma or serum from red blood cells comprising the steps of mounting a pair of spaced apart tubes coaxially related to one another head-to-head with a sharp-ended hollow needle disposed generally along the tube axes and between them, arranging the tubes in a vertical position one above the other in a centrifuge with the tubes closed with self-sealing stoppers, providing a partial vacuum in the upper tube, rotating the tubes at high speed about an axis parallel to and spaced from the axis of the tubes and needle, after separation of the red blood cells from the plasma and serum causing the tubes while still being rotated to be moved relative to one another such as to cause the needle to enter both tubes through the stoppers, separating the tubes while still being rotated by the centrifuge whereby to remove the needle from both tubes.
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: June 4, 2002
    Inventors: Manfred Grumberg, Oren Zinder, James W. Winkelman, Jacob Schreibman