Abstract: Hoxb5 identifies long-term hematopoietic stem cells. Expression of Hoxb5 distinguishes between LT-HSCs and non-LT-HSCs, and the marker identifies substantially all LT-HSC in the bone marrow. By utilizing fluorescent proteins under the endogenous expression control of Hoxb5, LT-HSC can be monitored and isolated, including without limitation detection and monitoring of HSC in bone morrow; production of LT-HSC from pluripotent stem cells such as iPS cells; for analysis of early stage LT-HSC; in screening methods for expansion and manipulation of LT-HSC, and the like.

Abstract: Hoxb5 identifies long-term hematopoietic stem cells. Expression of Hoxb5 distinguishes between LT-HSCs and non-LT-HSCs, and the marker identifies substantially all LT-HSC in the bone marrow. By utilizing fluorescent proteins under the endogenous expression control of Hoxb5, LT-HSC can be monitored and isolated, including without limitation detection and monitoring of HSC in bone morrow; production of LT-HSC from pluripotent stem cells such as iPS cells; for analysis of early stage LT-HSC; in screening methods for expansion and manipulation of LT-HSC, and the like.

Abstract: A method for improving the low temperature impact strength of a thermoplastic polyblend of PETG and SAN which method comprises incorporating therein an effective amount of a dispersant selected from the group consisting of mono- and di-carboxylic acids containing 6 to 36 carbon atoms; alkali and alkaline-earth metal salts and amides of such acids; and aliphatic alcohols containing 6 to 36 carbon atoms.

Abstract: A water demineralizer system and method is provided in which at least three beds of resin particles are connected in series flow arrangement preferably within a single vessel for substantially removing metal ions such as calcium and magnesium from water feed by exchange with hydrogen ions. The raw feed water flows first through an upper cation resin bed, then through an intermediate anion resin bed, and then through a lower bed of mixed cation and anion resins, and preferably flows downwardly through the beds. After the resin beds become saturated with metal ions from the feed water, mainly by calcium and magnesium ions, the beds are regenerated by first backwashing with water, then chemically treating with acid and caustic solution, followed by bed rinsing, air mixing and backflushing with water prior to further use for demineralizing the feed water.

Abstract: A process is disclosed in which a spent mixed anion/cation exchange resin bed is hydraulically separated into cation, anion and interface resin cuts. The interface resin cut is further classified by various physical separation techniques. Cation and anion resins are separately chemically regenerated. In an alternative embodiment cation resin fines are physically separated from the anion resin cut.