Patents by Inventor Jan E. Carette

Jan E. Carette has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MAMMALIAN GENETICS AND USES THEREOF
    Publication number: 20230374544
    Abstract: The invention provides compositions and methods for performing mammalian cell genetics, e.g., genetic screens, using near-haploid cells. The invention further provides genes and gene products isolated using the inventive methods and methods of use thereof.
    Type: Application
    Filed: March 30, 2023
    Publication date: November 23, 2023
    Inventors: Thijn R. Brummelkamp, Jan E. Carette
  • Compositions and methods for mammalian genetics and uses thereof
    Patent number: 11667928
    Abstract: The invention provides compositions and methods for performing mammalian cell genetics, e.g., genetic screens, using near-haploid cells. The invention further provides genes and gene products isolated using the inventive methods and methods of use thereof.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: June 6, 2023
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Thijn R. Brummelkamp, Jan E. Carette
  • COMPOSITIONS AND METHODS FOR MAMMALIAN GENETICS AND USES THEREOF
    Publication number: 20190376079
    Abstract: The invention provides compositions and methods for performing mammalian cell genetics, e.g., genetic screens, using near-haploid cells. The invention further provides genes and gene products isolated using the inventive methods and methods of use thereof.
    Type: Application
    Filed: December 7, 2018
    Publication date: December 12, 2019
    Inventors: Thijn R. Brummelkamp, Jan E. Carette
  • PLA2G16 as a target for antiviral compounds
    Patent number: 9011821
    Abstract: In some aspects, the invention provides compositions and methods for inhibiting viral infection. In some aspects, the invention provides compositions and methods useful for identifying antiviral compounds.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: April 21, 2015
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Thijn R. Brummelkamp, Jan E. Carette
  • PLA2G16 AS A TARGET FOR ANTIVIRAL COMPOUNDS
    Publication number: 20130219533
    Abstract: In some aspects, the invention provides compositions and methods for inhibiting viral infection. In some aspects, the invention provides compositions and methods useful for identifying antiviral compounds.
    Type: Application
    Filed: June 17, 2011
    Publication date: August 22, 2013
    Applicant: WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Thijn R. Brummelkamp, Jan E. Carette
  • Replication competent viruses capable of silencing virus inhibitory factor expression
    Patent number: 8318149
    Abstract: Described is a replication-competent virus capable of replication and having lytic capacity in target cells. The virus comprises in the genome thereof, at least one DNA sequence coding for a silencing factor functional in reducing expression of a target gene in the target cells, operably linked to one or more expression control sequences, functional in the target cells. The use thereof in the preparation of a medicament and the use thereof in a method for lysing target cells expressing a virus inhibitory factor are also described.
    Type: Grant
    Filed: October 9, 2006
    Date of Patent: November 27, 2012
    Assignee: Vereniging voor christelijik hoger onderwijs, wetenschappelijk onderzoek en patientenzorg
    Inventors: Jan E. Carette, Victor W. van Beusechem
  • COMPOSITIONS AND METHODS FOR MAMMALIAN GENETICS AND USES THEREOF
    Publication number: 20120190011
    Abstract: The invention provides compositions and methods for performing mammalian cell genetics, e.g., genetic screens, using near-haploid cells. The invention further provides genes and gene products isolated using the inventive methods and methods of use thereof.
    Type: Application
    Filed: July 9, 2010
    Publication date: July 26, 2012
    Inventors: Thijn R. Brummelkamp, Jan E. Carette