Patents by Inventor Jan-Eric W. Ahlfors

Jan-Eric W. Ahlfors has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Autogenic living scaffolds and living tissue matrices: methods and uses thereof
    Patent number: 10226548
    Abstract: The present invention is drawn to a 3-dimensional cell-produced scaffold construct comprising cells and the extracellular matrix that has been produced and arranged by these cells.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: March 12, 2019
    Assignee: GENESIS TECHNOLOGIES LIMITED
    Inventor: Jan-Eric W. Ahlfors
  • METHODS FOR REPROGRAMMING CELLS AND USES THEREOF
    Publication number: 20160160184
    Abstract: Described herein are reprogrammed cells, and methods for cell dedifferentiation, transformation and eukaryotic cell reprogramming. Also descried are cells, cell lines, and tissues that can be transplanted in a patient after steps of in vitro dedifferentiation and in vitro reprogramming. In particular embodiments the cells are Stem-Like Cells (SLCs), including Neural Stem-Like Cells (NSLCs), Cardiac Stem-Like Cells (CSLC), Hematopoietic Stem-Like Cells (HSLC), Pancreatic Progenitor-Like Cells, and Mesendoderm-like Cells. Also described are methods for generating these cells from human somatic cells and other types of cells. Also provided are compositions and methods of using of the cells so generated in human therapy and in other areas.
    Type: Application
    Filed: December 3, 2015
    Publication date: June 9, 2016
    Inventors: Jan-Eric W. AHLFORS, Rouwayda EL-AYOUBI
  • Autogenic Living Scaffolds and Living Tissue Matrices: Methods and Uses Thereof
    Publication number: 20150273112
    Abstract: The present invention is drawn to a 3-dimensional cell-produced scaffold construct comprising cells and the extracellular matrix that has been produced and arranged by these cells.
    Type: Application
    Filed: February 18, 2015
    Publication date: October 1, 2015
    Inventor: Jan-Eric W. Ahlfors
  • Acellular bioabsorbable tissue regeneration matrices
    Patent number: 8268361
    Abstract: The present invention provides methods and compositions useful in the regeneration of damaged, lost and/or degenerated tissue in humans and animals. In certain embodiments, the present invention provides an acellular bioabsorbable tissue regeneration matrix, methods of making such a matrix, and methods of using such a matrix for the regeneration of damaged, lost and/or degenerated tissue. In certain embodiments, methods and compositions of the present invention are useful in the treatment of damaged, lost and/or degenerated nerve tissue.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: September 18, 2012
    Inventor: Jan-Eric W. Ahlfors
  • Autogenic Living Scaffolds and Living Tissue Matrices: Methods and Uses Thereof
    Publication number: 20120156182
    Abstract: The present invention is drawn to a 3-dimensional cell-produced scaffold construct comprising cells and the extracellular matrix that has been produced and arranged by these cells.
    Type: Application
    Filed: October 24, 2011
    Publication date: June 21, 2012
    Inventor: Jan-Eric W. Ahlfors
  • Autogenic living scaffolds and living tissue matrices: methods and uses thereof
    Patent number: 8043614
    Abstract: The present invention is drawn to a 3-dimensional cell-produced scaffold construct comprising fibroblasts and the extracellular matrix that has been produced and arranged by these cells. The constructs promote the differentiation, dedifferentiation and/or transdifferentiation of cells and/or formation of tissue in vitro and in vivo, while at the same time promoting cell growth, proliferation, migration, and acquisition of in vivo-like morphology.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: October 25, 2011
    Inventor: Jan-Eric W. Ahlfors