Abstract: A base station (1) and a bioprocess system (3), wherein said base station (1) comprises: a frame or housing (5), wherein said frame or housing comprises a number of valves (7a-f, 9a-d, 11a-f, 13a-e, 15a-f) into which a disposable tubing set (21) during run of the system is provided such that at least one inlet (23a-j) of the disposable tubing set is connected to at least one outlet (25a-f) of the disposable tubing set via a bioprocess separation device (31) of the bioprocess system (3); and a movable pump holding device (35), which can be provided in at least two different positions, whereof one is within the frame or housing (5) and another is at least partly outside the frame or housing (5) and which comprises at least one pump main body (37), said pump main body comprising a connection (39) configured for connecting to a disposable pump connection part (27) comprised in the disposable tubing set (21).

Abstract: A base station (1) and a bioprocess system (3), wherein said base station (1) comprises: a frame or housing (5), wherein said frame or housing comprises a number of valves (7a-f, 9a-d, 11a-f, 13a-e, 15a-f) into which a disposable tubing set (21) during run of the system is provided such that at least one inlet (23a-j) of the disposable tubing set is connected to at least one outlet (25a-f) of the disposable tubing set via a bioprocess separation device (31) of the bioprocess system (3); a movable pump holding device (35), which can be provided in at least two different positions, whereof one is within the frame or housing (5) and another is at least partly outside the frame or housing (5) and which comprises at least one pump main body (37), said pump mainbody comprising a connection (39) configured for connecting to a disposable pump connection part (27) comprised in the disposable tubing set (21).

Abstract: A base station (1) and a bioprocess system (3), wherein said base station (1) comprises: a frame or housing (5), wherein said frame or housing comprises a number of valves (7a-f, 9a-d, 11a-f, 13a-e, 15a-f) into which a disposable tubing set (21) during run of the system is provided such that at least one inlet (23a-j) of the disposable tubing set is connected to at least one outlet (25a-f) of the disposable tubing set via a bioprocess separation device (31) of the bioprocess system (3); a movable pump holding device (35), which can be provided in at least two different positions, whereof one is within the frame or housing (5) and another is at least partly outside the frame or housing (5) and which comprises at least one pump main body (37), said pump mainbody comprising a connection (39) configured for connecting to a disposable pump connection part (27) comprised in the disposable tubing set (21).

Abstract: There is provided a method of preparing a mixed liquid having a first property and a second property. The method includes providing a first set of liquids, a second set of liquids, and a third set of liquids. The method includes combining the provided sets of liquids. Further, the method includes varying at least one of the liquid flows of the first and second sets and at least one liquid flow of the third set to adjust the first property and the second property to their respective predetermined values in the resulting mixed liquid flow.

Abstract: A method for preparing a liquid flow having pre-defined characteristics by mixing liquid flows of at least two different component stock solutions with each other comprises the steps of determining a selected property value for one or more of the stock solutions by sensing, in a flow of each stock solution separately, at least one characteristic related to the property value for the stock solution, and based on the determined property value or values, mixing the stock solution flows in mixing ratios giving the desired mixed liquid flow. A system for carrying out the method comprises sensor means and a control unit, wherein the control unit is arranged to evaluate the characteristics sensed by the sensor means and provide relative ratios of stock solutions required to obtain a mixed liquid flow having the pre-defined characteristics.

Abstract: A simulator device configured to replace a filtration unit in a crossflow filtration system comprises a feed inlet (41), a first flow path (43) connected to the feed inlet (41) for simulating a retentate flow in the filtration unit, and a second flow path (44) connected to the feed inlet (for simulating a permeate flow in the filtration unit. Adjustable valve means (45, 46) are provided for controlling at least one of the simulated retentate flow and the simulated permeate flow.

Abstract: A method of preparing a mixed liquid flow having predetermined characteristics, including a predetermined value of a first property and a predetermined value of a second property, comprising the steps of: a) providing a first set of at least one liquid flow each having a different first value of the first property; b) providing a second set of at least one liquid flow each having a different second value of the first property; c) providing a third set of at least one liquid flow of solvent; d) combining the provided liquid flows; and e) varying at least one of the liquid flows of the first and second sets and at least one liquid flow of the third set to adjust the first property and the second property to their respective predetermined values in the resulting mixed liquid flow.

Abstract: A method for preparing a liquid flow having pre-defined characteristics by mixing liquid flows of at least two different component stock solutions with each other comprises the steps of determining a selected property value for one or more of the stock solutions by sensing, in a flow of each stock solution separately, at least one characteristic related to the property value for the stock solution, and based on the determined property value or values, mixing the stock solution flows in mixing ratios giving the desired mixed liquid flow. A system for carrying out the method comprises sensor means and a control unit, wherein the control unit is arranged to evaluate the characteristics sensed by the sensor means and provide relative ratios of stock solutions required to obtain a mixed liquid flow having the pre-defined characteristics.

Abstract: A simulator device configured to replace a filtration unit in a crossflow filtration system comprises a feed inlet (41), a first flow path (43) connected to the feed inlet (41) for simulating a retentate flow in the filtration unit, and a second flow path (44) connected to the feed inlet (for simulating a permeate flow in the filtration unit. Adjustable valve means (45, 46) are provided for controlling at least one of the simulated retentate flow and the simulated permeate flow.