Abstract: An acoustic probe (100, 300) includes an acoustic transducer (15, 444), and a plurality of variably-refracting acoustic lens elements (10, 210a, 210b, 442) coupled to the acoustic transducer. Each variably-refracting acoustic lens element has at least a pair of electrodes (150, 160) adapted to adjust at least one characteristic of the variably-refracting acoustic lens element in response to a selected voltage applied across the electrodes. In one embodiment, each variably-refracting acoustic lens element includes a cavity, first and second fluid media (141, 142) disposed within the cavity, and the pair of electrodes. The speed of sound of an acoustic wave in the first fluid medium is different than the speed of sound of the acoustic wave in the second fluid medium. The first and second fluid media are immiscible with respect to each other, and the first fluid medium has a substantially different electrical conductivity than the second fluid medium.

Abstract: A catheter apparatus includes an elongated body having proximal and distal ends, and an acoustic transducer disposed proximate the distal end of the elongated body. A variably-refracting acoustic lens is provided to dynamically adjust a direction associated with an acoustic wave coupled to the acoustic transducer in response to one or more control signals provided thereto.

Abstract: A vacuum cleaning device comprises a unit (1) for aerodynamically affecting dust particles and/or a surface to be cleaned. The unit (1) comprises a housing (30) having a housing wall (31) encompassing two internal sections (20, 22), and a movable surface (11) arranged at an interface of the two sections (20, 22), wherein a portion (32) of the housing wall (31) delimiting a first section (20) is provided with at least one opening (21), and wherein means for actuating the movable surface (11) are arranged in a second section (22). A portion (33) of the housing wall (31) delimiting the second section (22) is adapted to at least hinder exchange of air between an inside of this section (22) and an outside of the housing (30) at the location of this section (22), in order to at least hinder a migration of dust to the second section (22).

Abstract: A vacuum cleaning device comprises a unit (1) for aerodynamically affecting dust particles and/or a surface (40) to be cleaned in order for the particles to become dislodged from the surface (40) and to be received by the unit (1). The unit (1) comprises a housing (10) having an internal space (11) enclosed by a housing wall (12) in which at least one opening (13) is arranged, a movable surface (30) which is integrated in the housing wall (12), and means (31) for actuating the movable surface (30), which are adapted to realize an oscillating movement of the surface (30) that causes air to alternately be drawn into the housing (10) through the opening (13) and expelled from the housing (10) through the opening (13). At least a portion of the housing wall (12), particularly a portion of the housing wall (12) in which the opening (13) is located, is movably arranged in the unit (1).

Abstract: An ultrasonic assembly suited for attachment to a catheter, e.g. for medical treatment. The ultrasonic assembly includes an adjustable ultrasonic focus mechanism arranged in connection with the ultrasonic transducer to adjust focus of ultrasonic waves generated by the transducer. The ultrasonic focus mechanism includes a fluid focus lens with at least two fluids separated by an interface such that ultrasonic waves are substantially reflected at the interface. At least two electrodes are arranged in connection with the fluid focus lens so as to allow adjustment of the interface shape, e.g. a curvature of the interface, when a voltage is applied to the electrodes. In preferred embodiments the electrodes are arranged so as to allow adjustment of the fluid focus lens in an elevation direction as well as in a radial direction. In simple embodiments with rotational symmetric geometry with the transducer positioned in the center of the fluid focus lens, ultrasonic waves can be focused in an annular ring. This is e.

Abstract: A vacuum cleaning device comprises a unit (1) in which an oscillating airflow is generated which substantially zero net flow and an asymmetry between the suction and the blowing phases, such that in the blowing phase a jet is generated. A generator (31) which is needed for generating the oscillating airflow comprises a movable surface (30) which is integrated in a wall (12) of a housing (10) having an internal space (11) and at least one opening (13) for allowing air to flow to and from the internal space (11). The jet can be generates when the so-called Strouhal number, being the frequency of the movement of the movable surface (30) multiplied by a characteristic dimension of the opening (13) and divided by the velocity of the air in the opening (13), is not higher than a predetermined maximum.

Abstract: The invention relates to an energy application apparatus for applying energy to an object. A plurality of energy application elements (4) applies energy to the object at different locations and at least one ultrasound element (18) generates an ultrasound signal being indicative of a property of the object at the different locations, wherein at least one energy application element is individually controlled depending on an energy application influence, in particular, an ablation depth, determined for the location at which the at least one energy application element applies energy from the ultrasound signal. Thus, at least one local control point for applying energy to the object is provided, thereby improving the control of applying energy to the object.

Abstract: The present disclosure provides advantageous systems and methods for significantly increasing the sensitivity and selectivity for diagnostic procedures, e.g., optical biopsy. The disclosed systems and methods use a highly non-linear effect, the so-called photon avalanche. In the regime close to the avalanche threshold, small differences in density of the probe-ion under investigation or the excitation power can result in very large changes in up-conversion emission intensity. Through this effect, it becomes possible to accurately measure the signal of an optical biopsy probe-ion only in the location(s) where its concentration is highest, while at the same time significantly reducing or eliminating measurement of background signal from probe-ions distributed with a somewhat lower concentration throughout the measurement volume. Also background auto-fluorescence of the surrounding healthy tissue is essentially absent with this technique.

Abstract: The disclosure is directed to a system for variably refracting, and is transparent for, ultrasound as well as for light. By choosing liquids with the right optical and acoustical properties, it is possible to variably refract (including focusing and deflecting or steering) ultrasound while not affecting the refraction of light, or vice versa. Two lenses in series, or preferably one lens, allow for variably refracting ultrasound and light.

Abstract: The present invention relates to a system (100) for combined ablation and ultrasound imaging of associated tissue (40), which is particularly useful for use in an ablation process. The system comprises an interventional device (20) with an ultrasouond transducer and an ablation unit. During an ablation process, the interventional device (20) can be applied for both ablation and imaging of the tissue (40) subject to the ablation. A controlling unit (CTRL) is further comprised within the system, and arranged to calculate a predictor value based on one or more signals from the ultrasound transducer, where the predictor value relates to a risk of impending tissue damage due to a rapid release of bubble energy. According to a specific embodiment, a primary signal is sent if the predictor value exceeds a threshold value, so that proper measures can be taken.

Abstract: A sensor probe for detecting an environmental state within a bodily lumen includes an elongated body having an optical guide with an outcoupling surface, which is part of an end surface of the elongated body, facing a reflective surface of an overhanging part. The sensor probe further includes a photodetector which detects a property of light which is composed of light in the optical guide that is reflected from the outcoupling surface of the optical guide and of light in the optical guide that is reflected from the overhanging part. The sensor probe also includes a hydrogel material having a property that changes when getting into contact with an environmental material and/or when detecting an environmental change. The hydrogel material is provided between the end surface of the elongated body and the overhanging part.

Abstract: An adjustable fluid type lens system is provided that allows e.g. ultrasound imaging through the lens during adjustment of the lens. The lens includes a container enclosing two immiscible fluids, e.g. water and oil, being in contact with each other at an interface. Incoming waves are then refracted at this interface. The shape of the interface, and thereby the refraction property, is adjustable by adjusting a voltage applied to the lens. The two fluids are selected such that they together exhibit a mechanical damping which is critical or near critical. A control circuit generates the electric voltage for adjusting the refraction from one value to another, the control circuit being arranged to change the electric voltage such that a rate of voltage change is limited to avoid oscillation of the interface, thereby adjusting refraction of incoming waves at the interface in a continuous manner.

Abstract: The invention relates to a sterilization coat (1) for sterilizing a device (2) like a medical detection device, wherein the sterilization coat (1) is adapted to be arranged on the device (2) and comprises a heating layer for sterilizing the device (2) by heating. If the sterilization coat (1) has been arranged on the device, several sterilization procedures can be performed by heating the sterilization coat (1) using the heating layer. Thus, it is not necessary to arrange sterile plastic drapes around the device (2) each time a sterile device is needed, for example, before each medical interventional procedure. If a sterilization of the device (2) is needed, the heating layer heats the device (2) for sterilizing. This simplifies the procedure for sterilizing the device (2).

Abstract: The present invention relates to a catheter (20) adapted for open-loop irrigated ablation, such as RF ablation, of a tissue (40). Said catheter has a distal tip (22) with an ablation entity (15) adapted for performing ablation of the tissue, an irrigation hole (21) and an ultrasound transducer (5) adapted for transmitting and/or receiving ultrasonic waves. The ultrasound transducer is disposed behind or in the irrigation hole of the catheter, so as to allow an irrigation fluid to flow out of the irrigation hole, and so as to allow transmitting and/or receiving the ultrasonic waves through the irrigation hole. The invention also relates to an imaging system and to a corresponding method for operating a catheter.

Abstract: The present invention relates to an apparatus for determining a property of a heart. The apparatus comprises a catheter (5), which comprises a first property sensing unit for sensing a contraction signal indicative of a reoccurring local contraction of the heart (2) at a sensing site of the heart (2). The apparatus further comprises a first property determining unit (8) for determining the reoccurring local contraction of the heart (2) at the sensing site from the sensed contraction signal as a first property of the heart (2). The reoccurring local contraction provides information about the heart (2), which can be used for a better and/or more reliable characterization of the heart (2).

Abstract: The invention relates to a visualization apparatus for visualizing quality of applying energy to an object. The quality of applying energy at a location on the object (3) is visualized based on a) a provided image of the object and b) a provided quality value representing the quality of applying energy to the object at the location on the object (3), wherein a visual property assigning unit (9) assigns a visual property to the location depending on the quality value and a display(10) displays the provided image and the assigned visual property at the location on the object shown in the image. In general a person who applies energy to the object is focused on the location at which energy is applied. Since quality information is shown at the location on which the person is already focused, the quality dependent information can easily be absorbed by the person.

Abstract: An imaging system for imaging a viscoelastic medium is disclosed. The imaging system comprises a variable refractive lens (4) and a transducer system (5) for generating acoustic radiation. The imaging system is operated to alternate between first and second operating modes. While the variable refractive lens is operated to alternate between a first configuration and a second configuration, the transducer is operated to alternate between generating acoustic radiation for displacing the viscoelastic medium and acoustic radiation for imaging the displacement of the viscoelastic medium. In embodiments the variable refractive lens is a fluid focus lens. Moreover, in embodiments, the imaging system is integrated with a catheter-based interaction modality, such as a tissue ablation modality.

Abstract: The present invention relates to an acoustic device for ultrasonic imaging of an object (21). The device comprises an acoustic transducer (10 and an acoustic lens (20) arranged to variably refract the said acoustic pulse to and/or from the acoustic transducer. The acoustic lens comprising a first (L1) and a second fluid (L2) being separated by an acoustic interface (7), the normal of the said acoustic interface forming a relative angle of incidence (AI) with the said acoustic pulse, e.g. an electrowetting lens. The first and the second fluid of the acoustic lens (20) are specifically chosen so that the acoustic interface (7) has a reflection minima at a non-zero relative angle of incidence (AI). The invention is advantageous for obtaining an improved acoustic device having a substantially lower reflection in a broader interval of incidence angles as compared to hitherto seen ultrasonic imaging utilising acoustic lenses with two or more fluids as the active acoustic refracting entities.

Abstract: The present invention relates to a monitoring apparatus (101) for monitoring an ablation procedure. The monitoring apparatus (101) comprises an ultrasound signal providing unit for providing an ultrasound signal that depends on received echo series of an object (4) that is ablated. The monitoring apparatus (101) further comprises an ablation depth determination unit (103) for determining an ablation depth from the provided ultrasound signal. The ablation depth can be determined directly from the ultrasound signal and is an important parameter while performing an ablation procedure. For example, it can be used for determining the progress of ablation within the object (4) and for determining when the ablation has reached a desired progression.

Abstract: The present invention relates to a catheter for applying energy to an object. The catheter (5) has a longitudinal axis (7) and includes an energy applying unit (30) for applying energy to the object and a sensing unit (20) for sensing the object in a sensing direction (23). The sensing unit (20) is adapted to be rotatable with respect to the catheter (5) such that the angle (α) between the sensing direction (23) of the sensing unit (20) and the longitudinal axis (7) of the catheter (5) is adjustable. The sensing unit (20) can be adjusted during the application of energy to the object such that the sensing direction (23) of the sensing unit (20) points to the site to which the energy is applied, regardless of the angle that the catheter tip forms with the surface of the object at that site.