Abstract: Polypeptides comprising a FimH lectin domain comprising at least one an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject in need thereof by administration of the polypeptide are further described.

Abstract: The invention provides analytical methods for identifying and quantifying complex glycoconjugate compositions, in particular for the analysis of a glycoconjugate in a sample comprising at least 4 glycoconjugates.

Abstract: Polypeptides comprising a FimH lectin domain comprising at least one an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject in need thereof by administration of the polypeptide are further described.

Abstract: Polypeptides comprising a FimH lectin domain comprising an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject in need thereof by administration of the polypeptide are further described.

Abstract: Polypeptides comprising a FimH lectin domain comprising an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject in need thereof by administration of the polypeptide are further described.

Abstract: Polypeptides comprising a FimH lectin domain comprising at least one an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject in need thereof by administration of the polypeptide are further described.

Abstract: Polypeptides comprising a FimH lectin domain comprising an amino acid mutation that causes the FimH lectin domain to be in the low affinity conformation for mannose are described. Pharmaceutical compositions which comprise such polypeptides and methods of stimulating an immune response in a subject in need thereof by administration of the polypeptide are further described.

Abstract: A gripper device comprises a gripper with a gripper arm rotatable around a rotation axis such that the gripper is movable between an open end position and a closed end position, and a hoisting device connected to the gripper and comprising a first cable and a second cable which are each connected with their one outer end to the gripper and are each connected with their other outer end to respectively a first and second hoisting means for raising and lowering the gripper with the cables, wherein each hoisting means is, driven by a separate drive, wherein a controller transmits the same control signal to both drives for the purpose of raising or lowering the gripper, and each drive comprises a motor with internal slippage or a slippage coupling so that synchronous running of the hoisting means is automatically realized.

Abstract: A gripper device comprises a gripper with a gripper arm rotatable around a rotation axis such that the gripper is movable between an open end position and a closed end position, and a hoisting device connected to the gripper and comprising a first cable and a second cable which are each connected with their one outer end to the gripper and are each connected with their other outer end to respectively a first and second hoisting means for raising and lowering the gripper with the cables, wherein each hoisting means is, driven by a separate drive, wherein a controller transmits the same control signal to both drives for the purpose of raising or lowering the gripper, and each drive comprises a motor with internal slippage or a slippage coupling so that synchronous running of the hoisting means is automatically realized.