Patents by Inventor Jan Hendrik van Ee

Jan Hendrik van Ee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transformed industrial bacillus strains and methods for making and using them
    Patent number: 6083718
    Abstract: Novel methods and novel industrial unicellular microorganism strains, particularly industrial Bacillus strains, are provided for enhanced production of endogenous and exogenous polypeptides. Cloning vehicles containing the gene expressing the polypeptide of interest are introduced into a compatible host. Transformed hosts harboring the introduced vehicle in a stable way by integration of the vehicle into the host cells chromosome are selected. Efficient transfer of the vehicle containing the gene of interest is achieved, with the resulting industrial strain transformants being effective, stable producers of the desired polypeptide product.
    Type: Grant
    Filed: November 5, 1997
    Date of Patent: July 4, 2000
    Assignee: Gist-Brocades, N.V.
    Inventors: Johan Pieter Marinus Sanders, Johannes Abel Van Den Berg, Peter Michael Andreoli, Yvonne Johanna Vos, Jan Hendrik Van Ee, Leo J. S. M. Mulleners
  • Transformed industrial bacillus strains and methods for making and using them
    Patent number: 5716807
    Abstract: Novel methods and novel industrial unicellular microorganism strains, particularly industrial Bacillus strains, are provided for enhanced production of endogenous and exogenous polypeptides. Cloning vehicles containing the gene expressing the polypeptide of interest are introduced into a compatible host. Transformed hosts harboring the introduced vehicle in a stable way by integration of the vehicle into the host cells chromosome are selected. Efficient transfer of the vehicle containing the gene of interest is achieved, with the resulting industrial strain transformants being effective, stable producers of the desired polypeptide product.
    Type: Grant
    Filed: August 16, 1996
    Date of Patent: February 10, 1998
    Assignee: Gist-Brocades
    Inventors: Johan Pieter Marinus Sanders, Johannes Abel Van den Berg, Peter Michael Andreoli, Yvonne Johanna Vos, Jan Hendrik van Ee, Leo J. S. M. Mulleners