Patents by Inventor Jan M. Casadei

Jan M. Casadei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prodrugs activated by targeted catalytic proteins
    Patent number: 6702705
    Abstract: Catalytic antibodies are disclosed. The catalytic antibodies are specific for prodrug compounds. The catalytic antibodies enhance cleavage of an active drug moiety from a prodrug residue, thereby activating the drug.
    Type: Grant
    Filed: February 22, 1995
    Date of Patent: March 9, 2004
    Assignee: IGEN International, Inc.
    Inventors: Reid von Borstel, Jan M. Casadei, Balreddy Kamireddy, John Kenten, Mark T. Martin, Richard J. Massey, Andrew D. Napper, David M. Simpson, Rodger Smith, Richard C. Titmas, Richard O. Williams
  • Prodrugs activated by targeted catalytic proteins
    Publication number: 20030096765
    Abstract: Disclosed and claimed are prodrugs activated by catalytic proteins, such as enzymes and catalytic antibodies. The invention comprehends such prodrugs, as well as haptens, to elicit catalytic antibodies to activate the prodrugs. The prodrugs are useful as cytotoxic chemotherapeutic agents; e.g., as antitumor agents.
    Type: Application
    Filed: July 25, 2002
    Publication date: May 22, 2003
    Applicant: Igen, Inc.
    Inventors: John Henry Kenten, Reid Von Borstel, Jan M. Casadei, Balreddy Kamireddy, Mark T. Martin, Richard J. Massey, Andrew D. Napper, David M. Simpson, Rodger G. Smith, Richard C. Titmas, Richard O. Williams
  • Prodrugs activated by targeted catalytic proteins
    Patent number: 6258360
    Abstract: Prodrugs that are activated by and conjugated to a catalytic antibody conjugated to a moiety that binds to a tumor cell population are provided.
    Type: Grant
    Filed: October 18, 1994
    Date of Patent: July 10, 2001
    Assignee: IGEN International, Inc.
    Inventors: Reid von Borstel, Jan M. Casadei, Balreddy Kamireddy, John Henry Kenten, Mark T. Martin, Richard J. Massey, Andrew D. Napper, David M. Simpson, Rodger G. Smith, Richard C. Titmas, Richard O. Williams