Abstract: A controller for controlling the operation of a crane has a control panel for the control of different functions of the crane, a two-way communication radio unit adapted to transmit and receive information from/to the controller, and a processing means connected to the control panel and the communication radio unit and adapted to control the function of the controller. The processing means, when in an operation mode, is adapted to communicate with the crane for controlling the operation of the crane, and when in a simulation mode, is adapted to communicate via the communication radio unit with a remote simulator device adapted to simulate the operation of a predefined crane. The communication radio unit is adapted to operate in the 2.4 GHz Bluetooth band. The same controller can thereby be used for both operation in the field and for a learning process.

Abstract: A battery device has a housing adapted to be attached to a controller for operating a crane and to be powered by the battery device, a battery cell, and electronic circuitry connected to the battery cell and electrically connectable to the controller. A memory is provided in the electronic circuitry, wherein a function of the controller depends on the information in the memory. By providing a controller adapted to operate in one of a plurality of operating modes, wherein the operating modes comprise any of the following: an operation mode for controlling the operation of a crane, a simulation mode for communicating with a simulation device for simulating a crane, and a demonstration mode for demonstration of the different functions of the controller for controlling a crane, a controller for a crane is provided in which the selection of functions can be done in a controlled and defined way.

Abstract: The invention relates to a purified antibody or fragment thereof that specifically binds an A? protofibril. The invention further relates to a composition that includes such antibodies. The invention also relates to using such antibodies and compositions for treating a patient having of suspected of having Alzheimer's disease.

Abstract: The invention relates to a purified antibody or fragment thereof that specifically binds an A? protofibril. The invention further relates to a composition that includes such antibodies. The invention also relates to using such antibodies and compositions for treating a patient having of suspected of having Alzheimer's disease.

Abstract: The present invention relates to prevention and treatment of Alzheimer's disease (AD). More specifically, the invention relates to use of a non-wild type protofibril or compound(s) with protofibril forming activity for active immunisation in the purpose of treating or preventing AD. The invention further relates to a peptide, A?-Arc, with high protofibril forming activity as well as several applications thereof, such as antibodies against said peptide for passive immunisation against AD.

Abstract: The invention relates to compounds of formula (I) or (II), which are of interest especially for inhibition of polymerization of amyloid ? peptide, as model substances for synthesis of amyloid ? peptide-ligands, as tools for the identification of other organic compounds with similar functional properties and/or as ligands for detection of amyloid deposits using e.g., positron emission tomography (PET).

Abstract: A method for the treatment of Alzheimer's disease in a subject having or suspected of having Alzheimer's disease by administering to the subject a therapeutically effective amount of an antibody wherein the antibody is raised against a protofibril that contains an A?-Arc peptide.

Abstract: The invention relates to compounds of formula (I) or (II), which are of interest especially for inhibition of polymerization of amyloid &bgr; peptide, as model substances for synthesis of amyloid &bgr; peptide-ligands, as tools for the identification of other organic compounds with similar functional properties and/or as ligands for detection of amyloid deposits using e.g., positron emission tomography (PET).