Patents by Inventor Jan Olof Gustav Karlsson

Jan Olof Gustav Karlsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitric oxide releasing chelating agents and their therapeutic use
    Patent number: 6391895
    Abstract: Chelating agents, in particular dipyridoxyl and aminopolycarboxylic acid based chelating agents, and their metal chelates, when linked directly or indirectly to at least one nitric oxide releasing moiety, or when use in combination with nitric oxide or a nitric oxide releasing moiety have been found to be effective in treating a variety of disorders. In particular, such compounds may be used in treating conditions associated with the presence of free radicals in the body, e.g. reperfusion injuries, and in reducing the cardiotoxicity of anti-tumor agents, e.g. anthracyclines and/or paclitaxel.
    Type: Grant
    Filed: June 23, 2000
    Date of Patent: May 21, 2002
    Assignee: Amersham Health AS
    Inventors: Robertson Towart, Jan Olof Gustav Karlsson, Lars Goran Wistrand, Hakan Malmgren
  • Use of chelating agents in the treatment of atherosclerotic conditions
    Patent number: 6310051
    Abstract: The invention provides the use of dipyridoxyl or aminopolycarboxylic acid based chelating agents, metal chelates and salts thereof, in the manufacture of a therapeutic agent for use in the treatment or prophylaxis of atherosclerosis and related conditions in the human or non-human animal body.
    Type: Grant
    Filed: June 23, 2000
    Date of Patent: October 30, 2001
    Assignee: Nycomed Imaging AS
    Inventors: Jan Olof Gustav Karlsson, Rolf Goran Gustav Andersson, Anders Olsson, Bo Zieden, Per Jynge, Tudor Griffith, Derek Grant, Robertson Towart, Helge Refsum