Patents by Inventor Jan Rosing

Jan Rosing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Regulation of Tissue Factor Activity by Protein S and Tissue Factor Pathway Inhibitor
    Publication number: 20080161425
    Abstract: The present invention relates to methods for the identification of compounds that increase or decrease the inhibitory effect of TFPI on tissue factor activity and/or Factor Xa activity and/or thrombin formation. The invention also relates to methods for the identification of compounds that increase or decrease the co-factor activity of Protein S in TFPI-mediated inhibition of tissue factor and/or Factor Xa activity. This invention also relates to a pharmaceutical composition comprising the compounds identifiable by such methods. The invention also relates to methods for the regulation of tissue factor activity by influencing the interaction between Protein S and Tissue Factor Pathway Inhibitor.
    Type: Application
    Filed: July 28, 2006
    Publication date: July 3, 2008
    Applicant: Universiteit Van Maastricht
    Inventors: Tilman M. Hackeng, Kristin M. Sere, Guido Tans, Jan Rosing
  • Evaluation of substances for altering and for increasing APC response
    Patent number: 5863896
    Abstract: The present invention provides methods, reagents, and test kits for evaluating the effect of a test composition on APC response by employing factor Va.sup.R506Q Methods and compositions for treating patients suffering from reduced APC response are also provided.
    Type: Grant
    Filed: November 9, 1995
    Date of Patent: January 26, 1999
    Assignee: Immuno AG
    Inventors: Jan Rosing, Guido Tans, Katalin Varadi, Hans Peter Schwarz