Patents by Inventor Jan-Thorsten Schantz
Jan-Thorsten Schantz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210030528Abstract: The present invention relates to the field of implants. In particular, the present invention relates to an implant for tissue reconstruction which comprises a scaffold structure that includes a void system for the generation of prevascularized connective tissue with void spaces for cell and/or tissue transplantation. Moreover, the present invention relates to a method of manufacturing such an implant, to the internal architecture of such an implant, to a removal tool for mechanical removal of space-occupying structures from such an implant, to a kit comprising such an implant and such a removal tool, to a removal device for the removal of superparamagnetic or ferromagnetic space-occupying structures from such an implant, as well as to a guiding device for providing feedback to a surgeon during the procedure of introducing transplantation cells into the void spaces generated upon removal of space-occupying structures from such an implant.Type: ApplicationFiled: October 9, 2020Publication date: February 4, 2021Inventors: Dietmar Werner Hutmacher, Jan-Thorsten Schantz, Paul Severin Wiggenhauser, Mohit Prashant Chhaya
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Patent number: 10799336Abstract: The present invention relates to the field of implants. In particular, the present invention relates to an implant for tissue reconstruction which comprises a scaffold structure that includes a void system for the generation of prevascularized connective tissue with void spaces for cell and/or tissue transplantation. Moreover, the present invention relates to a method of manufacturing such an implant, to the internal architecture of such an implant, to a removal tool for mechanical removal of space-occupying structures from such an implant, to a kit comprising such an implant and such a removal tool, to a removal device for the removal of superparamagnetic or ferromagnetic space-occupying structures from such an implant, as well as to a guiding device for providing feedback to a surgeon during the procedure of introducing transplantation cells into the void spaces generated upon removal of space-occupying structures from such an implant.Type: GrantFiled: September 9, 2015Date of Patent: October 13, 2020Assignee: Klinikum rechts der Isar der Technischen Universität MünchenInventors: Dietmar Werner Hutmacher, Jan-Thorsten Schantz, Paul Severin Wiggenhauser, Mohit Prashant Chhaya
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Patent number: 10736987Abstract: The present invention relates to the field of implants for the formation/regeneration of lymph nodes. In particular, the present invention relates to an implant comprising a biodegradable scaffold and lymph node fragments immobilized therein and/or thereon, to a method of manufacturing such an implant and to uses of such an implant.Type: GrantFiled: December 18, 2015Date of Patent: August 11, 2020Assignee: Klinikum rechts der Isar der Technischen Universität MünchenInventors: Min-Seok Kwak, Jan-Thorsten Schantz, Dietmar Werner Hutmacher, Mohit Prashant Chhaya, Elizabeth Rosado Balmayor
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Publication number: 20170354757Abstract: The present invention relates to the field of implants for the formation/regeneration of lymph nodes. In particular, the present invention relates to an implant comprising a biodegradable scaffold and lymph node fragments immobilized therein and/or thereon, to a method of manufacturing such an implant and to uses of such an implant.Type: ApplicationFiled: December 18, 2015Publication date: December 14, 2017Inventors: Min-Seok Kwak, Jan-Thorsten Schantz, Dietmar Werner Hutmacher, Mohit Prashant Chhaya, Elizabeth Rosado Balmayor
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Publication number: 20170258574Abstract: The present invention relates to the field of implants. In particular, the present invention relates to an implant for tissue reconstruction which comprises a scaffold structure that includes a void system for the generation of prevascularized connective tissue with void spaces for cell and/or tissue transplantation. Moreover, the present invention relates to a method of manufacturing such an implant, to the internal architecture of such an implant, to a removal tool for mechanical removal of space-occupying structures from such an implant, to a kit comprising such an implant and such a removal tool, to a removal device for the removal of superparamagnetic or ferromagnetic space-occupying structures from such an implant, as well as to a guiding device for providing feedback to a surgeon during the procedure of introducing transplantation cells into the void spaces generated upon removal of space-occupying structures from such an implant.Type: ApplicationFiled: September 9, 2015Publication date: September 14, 2017Inventors: Dietmar Werner Hutmacher, Jan-Thorsten Schantz, Paul Severin Wiggenhauser, Mohit Prashant Chhaya
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Patent number: 9492279Abstract: A bioabsorbable plug implant, suitable for bone tissue regeneration, includes a first portion, and a second portion extending outwardly from the first portion, the first and second portions formed from expandable material. A method for bone tissue regeneration includes providing a bioabsorbable plug implant, wherein the implant has a first portion and a second portion extending outwardly from the first portion. The first and second portions are formed from expandable material. The second portion is inserted into a defect or gap of a bone. The first surface engages the outside contour of the defect or gap. The plug implant is allowed to contact body fluids, thereby expanding the size of the plug implant so that the plug fits into the defect or gap.Type: GrantFiled: March 24, 2014Date of Patent: November 15, 2016Assignee: OSTEOPORE INTERNATIONAL PTE LTD.Inventors: Swee Hin Teoh, Kim Cheng Tan, Dietmar Hutmacher, Thiam Chye Lim, Jan-Thorsten Schantz, Ning Chou
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Publication number: 20140358238Abstract: A bioabsorbable plug implant, suitable for bone tissue regeneration, comprising a first portion, and a second portion extending outwardly from the first portion, the first and second portions formed from expandable material. A method for bone tissue regeneration comprising the steps of: providing a bioabsorbable plug implant, wherein the implant comprises a first portion and a second portion extending outwardly from the first portion, the first and second portions formed from expandable material; inserting the second portion into a defect or gap of a bone, the first surface engaging the outside contour of the defect or gap; allowing the plug implant to contact body fluids, thereby expanding the size of the plug implant so that the plug fits into the defect or gap.Type: ApplicationFiled: March 24, 2014Publication date: December 4, 2014Applicant: OSTEOPORE INTERNATIONAL PTE LTD.Inventors: Swee Hin TEOH, Kim Cheng TAN, Dietmar HUTMACHER, Thiam Chye LIM, Jan-Thorsten SCHANTZ, Ning CHOU
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Patent number: 7604987Abstract: The invention relates to a bioreactor comprising a chamber for containing cells or tissue cultures within a culture medium. The bioreactor also comprises a detector capable of detecting a change in one or more metabolites associated with growth of the cell or tissue cultures within the chamber and a chamber drive capable of rotating the chamber at a first speed about a first axis and a second speed about a second axis, the second axis being disposed at an angle relative to the first axis. In use, the magnitude of the first speed and the second speed are independently variable of each other.Type: GrantFiled: May 6, 2005Date of Patent: October 20, 2009Assignee: National University of SingaporeInventors: Dietmar W. Hutmacher, Swee Hin Teoh, Manoja Ranawake, Woon Shin Chong, Keng Soon Ting, Kay Chiang Chua, Than Myint, Chum Mok Puah, Toon Tien Foo, Jan-Thorsten Schantz
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Publication number: 20070083268Abstract: A bioabsorbable plug implant, suitable for bone tissue regeneration, comprising a first portion, and a second portion extending outwardly from the first portion, the first and second portions formed from expandable material. A method for bone tissue regeneration comprising the steps of: providing a bioabsorbable plug implant, wherein the implant comprises a first portion and a second portion extending outwardly from the first portion, the first and second portions formed from expandable material; inserting the second portion into a defect or gap of a bone, the first surface engaging the outside contour of the defect or gap; allowing the plug implant to contact body fluids, thereby expanding the size of the plug implant so that the plug fits into the defect or gap.Type: ApplicationFiled: November 22, 2004Publication date: April 12, 2007Applicant: Osteopore International Pte LtdInventors: Swee Teoh, Kim Cheng Tan, Dietmar Hutmacher, Thiam Lim, Jan-Thorsten Schantz, Ning Chou
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Publication number: 20060019388Abstract: The invention relates to a bioreactor comprising a chamber for containing cells or tissue cultures within a culture medium. The bioreactor also comprises a detector capable of detecting a change in one or more metabolites associated with growth of the cell or tissue cultures within the chamber and a chamber drive capable of rotating the chamber at a first speed about a first axis and a second speed about a second axis, the second axis being disposed at an angle relative to the first axis. In use, the magnitude of the first speed and the second speed are independently variable of each other.Type: ApplicationFiled: May 6, 2005Publication date: January 26, 2006Inventors: Dietmar Hutmacher, Swee Teoh, Manoja Ranawake, Woon Chong, Keng Ting, Kay Chua, Than Myint, Chum Puah, Toom Foo, Jan-Thorsten Schantz
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Publication number: 20040241835Abstract: The invention relates to a continuous flow dual axis bioreactor (10) for growing three-dimensional cell or tissue cultures. The bioreactor (10) includes a chamber (12) adapted to contain a three-dimensional matrix for growing three-dimensional cell or tissue cultures. A rotatable plate (14) supports the chamber (12) and is rotatable about a vertical axis (16). The rotatable plate (14) is supported on an rotary L-shaped bracket (20) that rotates about a horizontal axis (22). Two multi-flow fluid connectors (32,34) are provided to prevent any pipes connecting the chamber to a feed source or a product tank from being entangled and to allow continuous flow to and from the bioreactor (10).Type: ApplicationFiled: February 6, 2004Publication date: December 2, 2004Inventors: Dietmar W. Hutmacher, Swee Hin Teoh, Manoja Ranawake, Woon Shin Chong, Keng Soon Ting, Kay Chiang Chua, Than Myint, Chum Mok Puah, Toon Tien Foo, Jan-Thorsten Schantz