Patents by Inventor Jan Urban Kristoffer Hellstrand

Jan Urban Kristoffer Hellstrand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhanced activation of natural killer cells using an NK cell activator and a hydrogen peroxide scavenger or inhibitor
    Publication number: 20020119119
    Abstract: A method for providing activated natural killer (NK) cells comprising the steps of administering to a population of cells which includes lymphocytes and monocytes, an effective amount of an NK cell activating cytokine or a NK cell activating flavonoid, wherein said NK cell activating cytokine is not IL-2 or IFN-&agr;; and administering a compound effective to inhibit the production or release of hydrogen peroxide selected from the group consisting of histamine, other H2 receptor agonists, and serotonin.
    Type: Application
    Filed: February 12, 2002
    Publication date: August 29, 2002
    Inventors: Jan Urban Kristoffer Hellstrand, Svante Hermod Hermodsson
  • Enhanced activation of natural killer cells using an NK cell activator and a hydrogen peroxide scavenger or inhibitor
    Patent number: 6375946
    Abstract: A method for providing activated natural killer (NK) cells comprising the steps of administering to a population of cells which includes lymphocytes and monocytes, an effective amount of an NK cell activating cytokine or a NK cell activating flavonoid, wherein said NK cell activating cytokine is not IL-2 or IFN-&agr;; and administering a compound effective to inhibit the production or release of hydrogen peroxide selected from the group consisting of histamine, other H2 receptor agonists, and serotonin.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: April 23, 2002
    Assignee: Maxim Pharmaceuticals, Inc.
    Inventors: Jan Urban Kristoffer Hellstrand, Svante Hermod Hermodsson
  • Enhanced activation of natural killer cells using an NK cell activator and hydrogen peroxide scavenger or inhibitor
    Patent number: 6245563
    Abstract: A method for treating neoplastic disease comprising the steps of: administering to a patient receiving radiation therapy or chemotherapy, an effective amount of an NK cell activating cytokine or an NK cell activating flavonoid, wherein said NK cell activating cytokine is not IL-2 or IFN-&agr;; and administering to the patient a compound effective to inhibit the production or release of intracellular hydrogen peroxide selected from the group consisting of histamine, other H2 receptor agonists, and serotonin.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: June 12, 2001
    Assignee: Maxim Pharmaceuticals, Inc.
    Inventors: Jan Urban Kristoffer Hellstrand, Svante Hermod Hermodsson
  • Enhanced activation of natural killer cells using an NK cell activator and a hydrogen peroxide scavenger or inhibitor
    Patent number: 6071509
    Abstract: An improved method for the prevention of the inactivation of natural killer (NK) cells and the enhanced activation of NK cells in the presence of monocytes using a combination of a natural killer cell activator and a compound effective to inhibit the production or release of intracellular hydrogen peroxide, or a hydrogen peroxide scavenger, is disclosed. The method is useful, for example, in the treatment of solid tumors, metastases and viral infection.
    Type: Grant
    Filed: July 22, 1996
    Date of Patent: June 6, 2000
    Assignee: Maxim Pharmaceuticals, Inc.
    Inventors: Jan Urban Kristoffer Hellstrand, Svante Hermod Hermodsson
  • Enhanced activation of NK cells using an NK cell activator and a hydrogen peroxide scavenger or inhibitor
    Patent number: 6063373
    Abstract: An improved method for the prevention of the inactivation of natural killer (NK) cells and the enhanced activation of NK cells in the presence of monocytes using a combination of a natural killer cell activator and a compound effective to inhibit the production or release of intracellular hydrogen peroxide, or a hydrogen peroxide scavenger, is disclosed. The method is useful, for example, in the treatment of solid tumors, metastases and viral infection.
    Type: Grant
    Filed: September 17, 1997
    Date of Patent: May 16, 2000
    Assignee: Maxim Pharmaceuticals, Inc.
    Inventors: Jan Urban Kristoffer Hellstrand, Svante Hermod Hermodsson