Patents by Inventor Janela McClure

Janela McClure has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections
    Patent number: 5166050
    Abstract: Methods and composition for HIV diagnosis and treatment using monoclonal antibodies reactive with one or more neutralizing regions of HIV proteins, using the peptides or homologs thereof from that region, and using related nucleic acid segments. Exemplary neutralizing regions include selected portions of the env and gag genes from various HIV isolates. Monoclonal antibody secreting cell lines include HIV-gp110-1, -2, -3, -4, -5 and -6 (A.T.C.C. Accession Nos. HB9175, HB9176, HB9177, HV9405, HB9406 and HB9404, respectively) and HIV-p25-2, -3, -6 and -7 (A.T.C.C. Accession Nos. HB9407, HB9408, HB9409 and HB9410, respectively).
    Type: Grant
    Filed: December 7, 1990
    Date of Patent: November 24, 1992
    Assignee: Bristol-Myers Squibb Company
    Inventors: Mary K. Shriver, Larry H. Gosting, Edna S. Dickinson, Janela McClure, Elaine K. Thomas, Wesley L. Cosand
  • Human monoclonal antibody to lymphadenopathy-associated virus
    Patent number: 5087557
    Abstract: Human monoclonal antibodies capable of specifically reacting with an antigenic determinant of LAV/HTLV-III and cell lines producing those monoclonal antibodies are disclosed. The human monoclonal antibodies may be utilized in a method for determining the presence of LAV/HTLV-III in biological samples, or in a method for separating specific antigenic determinants of LAV/HTLV-III from a mixture. Pharmaceutical compositions containing such a human monoclonal antibody, and a method for significantly reducing the infectivity of LAV/HTLV-III in animals using the composition are also disclosed.
    Type: Grant
    Filed: March 19, 1990
    Date of Patent: February 11, 1992
    Assignee: Genetic Systems Corporation
    Inventor: Janela McClure