Patents by Inventor Janet Johnston
Janet Johnston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20070280942Abstract: The present invention provides a newly identified CD28 family member that functions as lymphocyte inhibitory receptor termed pG6b, which is expressed on T cells. Methods and compositions for modulating pG6b-mediated negative signaling and interfering with the interaction of its counter-receptor for therapeutic, diagnostic, and research purposes are also provided.Type: ApplicationFiled: May 14, 2007Publication date: December 6, 2007Inventors: Steven Levin, Frederick Ramsdell, Zeren Gao, Edward Howard, David Taft, Janet Johnston, Mark Rixon, LuAnne Hebb
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Publication number: 20070166794Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 23, 2006Publication date: July 19, 2007Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070098682Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 19, 2006Publication date: May 3, 2007Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070099269Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 16, 2006Publication date: May 3, 2007Inventors: JULIA NOVAK, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070098683Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 19, 2006Publication date: May 3, 2007Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070092485Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 23, 2006Publication date: April 26, 2007Inventors: JULIA NOVAK, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070066808Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 23, 2006Publication date: March 22, 2007Inventors: JULIA NOVAK, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070066807Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 20, 2006Publication date: March 22, 2007Inventors: JULIA NOVAK, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070059825Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 19, 2006Publication date: March 15, 2007Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070054320Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 19, 2006Publication date: March 8, 2007Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070048259Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 20, 2006Publication date: March 1, 2007Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070049529Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 20, 2006Publication date: March 1, 2007Inventors: JULIA NOVAK, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070048845Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 20, 2006Publication date: March 1, 2007Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070048260Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 20, 2006Publication date: March 1, 2007Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070041974Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: October 16, 2006Publication date: February 22, 2007Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Publication number: 20070014800Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.Type: ApplicationFiled: September 18, 2006Publication date: January 18, 2007Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
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Patent number: 5411884Abstract: The present invention is concerned with novel monoclonal antibody L53 which binds strongly to a glycoprotein antigen associated with human tumors, including carcinomas of the colon, breast, and lung, as well as melanomas. The antibody binds to normal human cells to a much lesser degree than to tumor cells. The antibody finds use in diagnostic methods for as the detection of malignant cells associated with tumors. Also disclosed is a novel 70,000-75,000 dalton glycoprotein antigen recognized by MAb L53. The L53 antigen is found on the cell surface of human tumor cells. The amino terminal amino acid sequence of this antigen is: ##STR1## in which X represents an unidentified amino acid.Type: GrantFiled: February 18, 1993Date of Patent: May 2, 1995Assignee: Oncogen Limited PartnershipInventors: Ingegerd Hellstrom, Karl E. Hellstrom, Hans Marquardt, Janet Johnston