Patents by Inventor Janet Plescia

Janet Plescia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds that inhibit Hsp90 protein-protein interactions with IAP proteins
    Patent number: 9035024
    Abstract: Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: May 19, 2015
    Assignee: University of Massachusetts
    Inventors: Dario C. Altieri, Janet Plescia, Whitney Salz
  • Compounds that inhibit Hsp90 protein-protein interactions with IAP proteins
    Patent number: 8420777
    Abstract: Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds.
    Type: Grant
    Filed: February 19, 2008
    Date of Patent: April 16, 2013
    Assignee: University of Massachusetts
    Inventors: Dario C. Altieri, Janet Plescia, Whitney Salz
  • Detection of survivin in the biological fluids of cancer patients
    Patent number: 7794926
    Abstract: The present invention includes a method for diagnosing cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing.
    Type: Grant
    Filed: April 18, 2006
    Date of Patent: September 14, 2010
    Assignee: Yale University
    Inventors: Dario Altieri, Robert Weiss, Shannon Smith, Victor Morris, legal representative, Marcia Wheeler, Janet Plescia
  • Detection of survivin in the biological fluids of cancer patients
    Patent number: 7776518
    Abstract: The present invention includes a method for diagnosing cancer and predicting recurrent cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: August 17, 2010
    Assignee: Yale University
    Inventors: Dario C. Altieri, Robert M. Weiss, Shannon D. Smith, Victor A. Morris, legal representative, Marcia A. Wheeler, Janet Plescia
  • COMPOUNDS THAT INHIBIT HSP90 PROTEIN-PROTEIN INTERACTIONS WITH IAP PROTEINS
    Publication number: 20080171693
    Abstract: Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds.
    Type: Application
    Filed: February 19, 2008
    Publication date: July 17, 2008
    Applicant: UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER
    Inventors: Dario C. Altieri, Janet Plescia, Whitney Salz
  • Compounds that inhibit Hsp90 protein-protein interactions with IAP proteins
    Patent number: 7342093
    Abstract: Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds.
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: March 11, 2008
    Assignee: University of Massachusetts
    Inventors: Dario C. Altieri, Janet Plescia, Whitney Salz
  • Detection of survivin in the biological fluids of cancer patients
    Publication number: 20070065842
    Abstract: The present invention includes a method for diagnosing cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing.
    Type: Application
    Filed: April 18, 2006
    Publication date: March 22, 2007
    Inventors: Dario Altieri, Robert Weiss, Shannon Smith, Victor Morris, Marcia Wheeler, Janet Plescia
  • Detection of survivin in the biological fluids of cancer patients
    Patent number: 7097966
    Abstract: The present invention includes a method for diagnosing cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing.
    Type: Grant
    Filed: January 11, 2002
    Date of Patent: August 29, 2006
    Assignee: Yale University
    Inventors: Dario C. Altieri, Robert M. Weiss, Victor A. Morris, legal representative, Marcia A. Wheeler, Janet Plescia, Shannon D. Smith, deceased
  • Compounds that inhibit Hsp90 protein-protein interactions with IAP proteins
    Publication number: 20060035837
    Abstract: Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds.
    Type: Application
    Filed: July 22, 2005
    Publication date: February 16, 2006
    Inventors: Dario Altieri, Janet Plescia, Whitney Salz
  • Detection of survivin in the biological fluids of cancer patients
    Publication number: 20040126775
    Abstract: The present invention includes a method for diagnosing cancer and predicting recurrent cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing.
    Type: Application
    Filed: June 18, 2003
    Publication date: July 1, 2004
    Inventors: Dario C. Altieri, Robert M. Weiss, Shannon D. Smith, Marcia A. Wheeler, Victor A. Morris, Janet Plescia
  • Detection of survivin in the biological fluids of cancer patients
    Publication number: 20020160395
    Abstract: The present invention includes a method for diagnosing cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing.
    Type: Application
    Filed: January 11, 2002
    Publication date: October 31, 2002
    Inventors: Dario C. Altieri, Robert M. Weiss, Shannon D. Smith, Victor A. Morris, Marcia A. Wheeler, Janet Plescia