Patents by Inventor Janey Ronxhi

Janey Ronxhi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microfluidic proximal tubule kidney-on-chip
    Patent number: 11841361
    Abstract: The present invention relates to microfluidic fluidic devices, methods and systems as microfluidic kidney on-chips, e.g. human Proximal Tubule-Kidney-Chip, Glomerulus (Kidney)-Chip, Collecting Duct (Kidney)-Chip. Devices, methods and systems are described for drug testing including drug transport and renal clearance. Further, such devices, methods and systems are used for determining drug-drug interactions and their effect upon renal transporter functions. Importantly, they may be used for pre-clinical and clinical drug development for treating kidney diseases and for personalized medicine.
    Type: Grant
    Filed: August 19, 2021
    Date of Patent: December 12, 2023
    Assignee: EMULATE, INC.
    Inventors: Kyung-Jin Jang, Janey Ronxhi, Josiah Sliz, Sauveur Jeanty, Sushma Jadalannagari, Ananth Nookala, Hyoungshin Park
  • Microfluidic proximal tubule kidney-on-chip
    Patent number: 11725190
    Abstract: The present invention relates to microfluidic fluidic devices, methods and systems as microfluidic kidney on-chips, e.g. human Proximal Tubule-Kidney-Chip, Glomerulus (Kidney)-Chip, Collecting Duct (Kidney)-Chip. Devices, methods and systems are described for drug testing including drug transport and renal clearance. Further, such devices, methods and systems are used for determining drug-drug interactions and their effect upon renal transporter functions. Importantly, they may be used for pre-clinical and clinical drug development for treating kidney diseases and for personalized medicine.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: August 15, 2023
    Assignee: EMULATE, INC.
    Inventors: Kyung-Jin Jang, Hyoungshin Park, Sauveur Jeanty, Janey Ronxhi, Sushma Jadalannagari, Geraldine A Hamilton, Catherine Karalis
  • DEVICES AND METHODS FOR SIMULATING A FUNCTION OF LIVER TISSUE
    Publication number: 20230159899
    Abstract: Provided herein relates to devices for simulating a function of a tissue and methods of using the same. In some embodiments, the devices can be used to simulate a function of a human liver tissue. In some embodiments, the devices can be used to simulate a function of a dog liver tissue. Endothelial cell culture media for long-term culture of endothelial cells are also described herein.
    Type: Application
    Filed: November 22, 2022
    Publication date: May 25, 2023
    Inventors: Geraldine Hamilton, Kyung Jin Jang, Suzzette Haney, Janey Ronxhi, Konstantia Kodella, Hyoungshin Park, Josiah Sliz, Debora Barreiros Petropolis, Daniel Levner, Monicah Otieno
  • MICROFLUIDIC PROXIMAL TUBULE KIDNEY-ON-CHIP
    Publication number: 20220042976
    Abstract: The present invention relates to microfluidic fluidic devices, methods and systems as microfluidic kidney on-chips, e.g. human Proximal Tubule-Kidney-Chip, Glomerulus (Kidney)-Chip, Collecting Duct (Kidney)-Chip. Devices, methods and systems are described for drug testing including drug transport and renal clearance. Further, such devices, methods and systems are used for determining drug-drug interactions and their effect upon renal transporter functions. Importantly, they may be used for pre-clinical and clinical drug development for treating kidney diseases and for personalized medicine.
    Type: Application
    Filed: August 19, 2021
    Publication date: February 10, 2022
    Inventors: Kyung-Jin Jang, Janey Ronxhi, Josiah Sliz, Sauveur Jeanty, Sushma Jadalannagari, Ananth Nookala, Hyoungshin Park
  • MICROFLUIDIC PROXIMAL TUBULE KIDNEY-ON-CHIP
    Publication number: 20200270582
    Abstract: The present invention relates to microfluidic fluidic devices, methods and systems as microfluidic kidney on-chips, e.g. human Proximal Tubule-Kidney-Chip, Glomerulus (Kidney)-Chip, Collecting Duct (Kidney)-Chip. Devices, methods and systems are described for drug testing including drug transport and renal clearance. Further, such devices, methods and systems are used for determining drug-drug interactions and their effect upon renal transporter functions. Importantly, they may be used for pre-clinical and clinical drug development for treating kidney diseases and for personalized medicine.
    Type: Application
    Filed: June 27, 2019
    Publication date: August 27, 2020
    Inventors: Kyung-Jin Jang, Hyoungshin Park, Sauveur Jeanty, Janey Ronxhi, Sushma jadalannagari, Geraldine A. Hamilton, Catherine Karalis
  • DEVICES AND METHODS FOR SIMULATING A FUNCTION OF A LIVER TISSUE
    Publication number: 20190093077
    Abstract: Provided herein relates to devices for simulating a function of a tissue and methods of using the same. In some embodiments, the devices can be used to simulate a function of a human liver tissue. In some embodiments, the devices can be used to simulate a function of a dog liver tissue. Endothelial cell culture media for long-term culture of endothelial cells are also described herein.
    Type: Application
    Filed: December 2, 2016
    Publication date: March 28, 2019
    Applicant: EMULATE, INC.
    Inventors: Geraldine Hamilton, Kyung Jin Jang, Suzzette Haney, Janey Ronxhi, Konstantia Kodella, Hyoungshin Park, Josiah Sliz, Debora Barreiros Petropolis, Daniel Levner