Abstract: A control circuit configured as a multi-criteria optimizer generates a radiation therapy treatment plan. The circuit then determines a resultant dose distribution as a function of the radiation therapy treatment plan and presents, on a display, at least a part of that resultant dose distribution. The latter may comprise, for example, presenting at least one isodose line on the display. The control circuit then detects user manipulation of a user interface. By one approach, this manipulation does not include corresponding immediate movement of any part of the presented resultant dose distribution itself. In particular, the detected user manipulation does not result in dragged movement of an isodose line on the display.

Abstract: Method for producing microfibrillated cellulose(MFC), wherein the method comprising the steps of: Pre-treating of chemical pulp, such that, the pulp reaches a Schopper-Riegler (SR) value above 50, and refining the pulp, at a consistency of 3-6%, in a refiner with refiner blades, wherein the height of the refiner blades is in the range 2-3 mm.

Abstract: The present invention relates to sulphonamide derivatives, whith a urea moiety. The invention also relates to the use of the derivatives as inhibitors of collagen receptor integrins, especially ?2?1 integrin inhibitors e.g. in connection with diseases and medical conditions that involve the action of cells and platelets expressing collagen receptors, their use as a medicament, e.g. for the treatment of thrombosis, inflammation, cancer and vascular diseases, pharmaceutical compositions containing them and a process for preparing them. The sulphonamide derivatives have the general formula (I) or (I?).

Abstract: Targeted advertising is disclosed. Advertiser-set targeted consumer advertising is saved with interest, location, and time as selection parameters for the targeted consumer. Immediate consumer-triggered interest information is received from a client apparatus of a consumer, and location information determining the present location of the client apparatus is also received. The immediate consumer-triggered interest information indicates immediate interest of the consumer in some good and/or service and/or brand and resulting from consumer interaction with a user interface of the client apparatus. It is searched, in response to receiving the immediate consumer triggered interest information, for such advertiser-set targeted consumer advertising whose interest selection parameter matches the interest information, whose location selection parameter matches the location information, and whose time selection parameter matches the present time.