Patents by Inventor Janina Cramer

Janina Cramer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10011827
    Abstract: The method for isolating nucleic acids from a food sample comprising the following steps: a) obtaining a food enrichment culture; b) transferring a portion of the food enrichment culture into a reaction vessel thereby providing a food enrichment sample and providing a water-immiscible phase in contact with the food enrichment culture; c) lysing the food enrichment sample to provide a lysed sample; d) isolating nucleic acids from the lysed sample. Food enrichment culture samples are known to contain high concentrations of organic and/or liposoluble inhibitors. By contacting the enrichment culture sample with a water-immiscible phase before the actual DNA extraction procedure starts, part of the lipophilic inhibitors is expected to cross the phase interface due to an enhanced solubility in the organic phase and thereby become depleted.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: July 3, 2018
    Assignee: QIAGEN GmbH
    Inventors: Janina Cramer, Sarah Fakih, Corinna Küppers, Holger Engel
  • Patent number: 9518983
    Abstract: The present invention relates to a method for purifying biomolecules or for analyzing whether an aqueous phase contains biomolecules by means of magnetic separation. The invention further relates to uses, to devices, and to kits that relate to the method according to the invention.
    Type: Grant
    Filed: March 25, 2010
    Date of Patent: December 13, 2016
    Assignee: QIAGEN, GmbH
    Inventor: Janina Cramer
  • Publication number: 20150056624
    Abstract: The method for isolating nucleic acids from a food sample comprising the following steps: a) obtaining a food enrichment culture; b) transferring a portion of the food enrichment culture into a reaction vessel thereby providing a food enrichment sample and providing a water-immiscible phase in contact with the food enrichment culture; c) lysing the food enrichment sample to provide a lysed sample; d) isolating nucleic acids from the lysed sample. Food enrichment culture samples are known to contain high concentrations of organic and/or liposoluble inhibitors. By contacting the enrichment culture sample with a water-immiscible phase before the actual DNA extraction procedure starts, part of the lipophilic inhibitors is expected to cross the phase interface due to an enhanced solubility in the organic phase and thereby become depleted.
    Type: Application
    Filed: February 28, 2013
    Publication date: February 26, 2015
    Inventors: Janina Cramer, Sarah Fakih, Corinna Küppers, Holger Engel
  • Publication number: 20120077285
    Abstract: The present invention relates to a method for purifying biomolecules or for analyzing whether an aqueous phase contains biomolecules by means of magnetic separation. The invention further relates to uses, to devices, and to kits that relate to the method according to the invention.
    Type: Application
    Filed: March 25, 2010
    Publication date: March 29, 2012
    Inventor: Janina Cramer
  • Publication number: 20110008846
    Abstract: The invention relates to an active enzyme of bacterial, fungal, viral, or archae origin, wherein the enzyme is coupled, preferably covalently coupled with at least one polymer having a molecular weight between about 500 to about 20,000 daltons selected from the group consisting of polyethylene glycol and polypropylene glycol. The invention relates in particular to uses thereof of such as in molecular biology as well as kits comprising such enzymes. In preferred embodiments the enzymes of the invention are nucleic acid modifying or replicating enzymes.
    Type: Application
    Filed: December 12, 2008
    Publication date: January 13, 2011
    Applicant: QIAGEN GMBH
    Inventors: Lars-Erik Peters, Nan Fang, Janina Cramer