Patents by Inventor Janine Orban

Janine Orban has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHEMICAL TREATMENT FOR REMOVING CELLULAR AND NUCLEAR MATERIAL FROM NATURALLY OCCURRING EXTRACELLULAR MATRIX-BASED BIOMATERIALS
    Publication number: 20100189759
    Abstract: A method is provided for sequential decellularization of an isolated tissue using solubilizing solutions comprising at least one oxidizing agent that removes all cellular and nuclear materials from the tissue while substantially maintaining the biological and, mechanical properties, and the biochemical properties of the resulting extracellular matrix.
    Type: Application
    Filed: April 2, 2010
    Publication date: July 29, 2010
    Applicant: DEPUY SPINE, INC.
    Inventors: Rangamani Padmini, Janine Orban, Prasanna Malaviya
  • Chemical treatment for removing cellular and nuclear material from naturally occurring extracellular matrix-based biomaterials
    Patent number: 7763459
    Abstract: A method is provided for sequential decellularization of an isolated tissue using solubilizing solutions comprising at least one oxidizing agent that removes all cellular and nuclear materials from the tissue while substantially maintaining the biological and, mechanical properties, and the biochemical properties of the resulting extracellular matrix.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: July 27, 2010
    Assignee: DePuy Spine, Inc.
    Inventors: Rangamani Padmini, Janine Orban, Prasanna Malaviya
  • Coated biomedical device and associated method
    Publication number: 20060068224
    Abstract: The present invention provides a halogen coated biomedical device and a method for producing the device. The method generally involves generating a plasma that affects the release of a halogen species from a source. The halogen reacts with the surface of the biomedical device to form a halogen coating.
    Type: Application
    Filed: September 30, 2004
    Publication date: March 30, 2006
    Inventors: George Grobe, Janine Orban, Mark Heldreth, Richard Tarr, Don Paquin, Jonathon Spanyer
  • Chemical treatment for removing cellular and nuclear material from naturally occurring extracellular matrix-based biomaterials
    Publication number: 20050260612
    Abstract: A method is provided for sequential decellularization of an isolated tissue using solubilizing solutions comprising at least one oxidizing agent that removes all cellular and nuclear materials from the tissue while substantially maintaining the biological and, mechanical properties, and the biochemical properties of the resulting extracellular matrix.
    Type: Application
    Filed: September 30, 2004
    Publication date: November 24, 2005
    Applicant: DePuy Spine, Inc.
    Inventors: Rangamani Padmini, Janine Orban, Prasanna Malaviya
  • Hybrid biologic-synthetic bioabsorbable scaffolds
    Publication number: 20050249771
    Abstract: A bioprosthetic device is provided for soft tissue attachment, reinforcement, and or reconstruction. The device comprises a naturally occurring extracellular matrix portion and a synthetic portion.
    Type: Application
    Filed: April 20, 2005
    Publication date: November 10, 2005
    Inventors: Prasanna Malaviya, Janine Orban, Philip Jenks, Terrence Whalen
  • Hybrid biologic-synthetic bioabsorbable scaffolds
    Publication number: 20050249772
    Abstract: A bioprosthetic device is provided for soft tissue attachment, reinforcement, and or reconstruction. The device comprises a naturally occurring extracellular matrix portion and a synthetic portion.
    Type: Application
    Filed: April 20, 2005
    Publication date: November 10, 2005
    Inventors: Prasanna Malaviya, Janine Orban
  • Implant device for cartilage regeneration in load bearing articulation regions
    Publication number: 20050125073
    Abstract: An implant device for cartilage regeneration in loading-bearing regions uses the osteochondral defect model. The implant is formed of resorbable polymeric materials. The implant is designed such that load is transmitted from the articulating surface of the bone platform through the implant to the entire area of subchondral bone of the bone platform. Application of load in this manner results in reduced subchondral bone resorption, leading to joint stabilization and maintenance of normal joint biomechanics. The implant allows for the incorporation therein of a resorbable scaffold or matrix material. The present implant solves the current inability to regenerate cartilage in load-bearing articulating surfaces using engineered scaffold devices.
    Type: Application
    Filed: December 8, 2003
    Publication date: June 9, 2005
    Inventors: Janine Orban, Herbert Schwartz, Nathaniel Grobe