Patents by Inventor Jantje R. G. Thiecke

Jantje R. G. Thiecke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of preparing aryl(homo)piperazines
    Patent number: 5463050
    Abstract: The present invention is concerned with a method for the preparation of a compound of the general formula 2 ##STR1## by reaction of a compound of the formula 3Ar--Y (3)with a compound of the general formula 4 ##STR2## wherein Ar means a (hetero)aryl group, preferably selected from phenyl, naphtyl, furyl, thienyl, pyridyl, bicylic heteroaryl and tricyclic heteroaryl, which (hetero)aryl group is optionally sustituted with one to five non-strongly-electron-withdrawing substituents;M is a metal from the groups I or II of the periodic table;R.sub.12 is an electronegative group; andis 0 or 1.The invention also relates to compounds prepared according to this method and to new substituted aryl(homo)piperazines.
    Type: Grant
    Filed: February 12, 1993
    Date of Patent: October 31, 1995
    Assignee: Duphar International Research, B.V.
    Inventors: Wolter Ten Hoeve, Jantje R. G. Thiecke, Hans Wynberg, Chris G. Kruse