Abstract: Devices, systems, and methods for a medication monitoring system are described. An example medication monitoring system for a user includes a container subassembly comprising one or more compartments, each compartment being configured to store medical equipment or medications prescribed to the user, and a lid of the container subassembly pivotally mounted on a first edge of the container subassembly and comprising a magnet at a second edge opposite to the first edge, and an electronics subassembly comprising a magnetic sensor coupled to the magnet in the lid of the container subassembly, and a communication module configured to communicate with a patient record comprising one or more medication regimens for the user.

Abstract: A medicament delivery device add-on is described. The medicament delivery device add-on has a first portion and a second portion, the first portion comprising at least one electronic component. The first portion is releasably attached to the second portion by a magnetic lock. Other related apparatus and methods are also described.

Abstract: A device is presented having an electronic circuit, where the device can be a medicament delivery device or a medicament delivery device add-on component that includes an electronic circuit having a temperature sensor configured to measure a temperature, where the electronic circuit is configured to passively remain in a first mode when the temperature is on a first side of a set temperature and to transition to a second mode when the temperature transitions to a second side of the set temperature. In some embodiments, the electronic circuit can have one or more of a feedback portion configured to switch from a first state to a second state in response to the electronic circuit transitioning from the first mode to the second mode, a lock, and a recordal portion to record when the electronic circuit transitions from the first mode to the second mode.

Abstract: A cover assembly that covers a medicament delivery member of a medicament container. The assembly having a housing extending along a longitudinal axis, a proximal end and a distal end. A cover member bi-directionally movable along the longitudinal axis relative to the housing, where the cover member has a tubular portion arranged to protrude from the proximal end of the housing, a biasing element arranged between the housing and the cover member configured to move the cover member, a locking member having a fixed end which is pivotally arranged to the housing and a free end which is releasably connected to the cover member. The cover assembly also has an actuator unit connected to the housing configured to interact with the free end of the locking member such that the locking member is able to lock and unlock the cover member in different positions.

Abstract: A system is presented including a monitoring device and a medicament delivery device, where the monitoring device is configured to be releasably connected to the medicament delivery device and wherein the monitoring device comprises an induction sensor configured to detect a state of an electrically conductive drive member of the medicament delivery device in an medicament delivery process through an electrical current which is generated by a magnet field by the induction sensor on the electrically conductive drive element.

Abstract: A system having a monitoring device and a medicament delivery device is presented wherein the monitoring device is configured to be releasably attached to the medicament delivery device and to monitor an operation of the medicament delivery device. The monitoring device has a body defining a cavity for receiving the medicament delivery device; a biased holding unit arranged in the body and configured to retain the medicament delivery device to the body in a secure state; wherein the biased b holding unit is movable within the body between a first position in which the medicament delivery device is in an unsecure state and a second position in which the medicament delivery device is in the secure state.

Abstract: A delivery member shield remover assembly is presented that includes a housing which extends along a longitudinal axis L and which has a proximal and a distal end; and a delivery member shield remover having a free end and a fixed end and wherein said delivery member shield remover is resiliently connected to the housing, wherein the fixed end is connected to the housing and the free end of the delivery member shield remover is configured to be positioned in a gap defined between the medicament container and the delivery member shield such that a distal movement of the movable medicament container in relation to the housing, forces the free end of the delivery member shield remover to move in a distal direction until the delivery member shield remover reaches a bias threshold and forces the delivery member shield to detach from the movable medicament container.

Abstract: A power pack assembly for a medicament delivery device is presented having a housing extending along a longitudinal axis and having a proximal and a distal end, a container carrier unit arranged longitudinally and bi-directionally movable in relation to the housing, a plunger pusher releasably connected to the container carrier unit, and an actuator unit connected to the plunger pusher, wherein the actuator unit is configured to drive the plunger pusher in a sequence in which the plunger pusher and the container unit are moved together distally relative to the housing until a virtual distal stop is met. Proximal movement of the plunger pusher causes the container carrier unit to interact with a proximal stop element of the housing whereby the plunger pusher is released from the container carrier unit and the plunger pusher continues to move proximally a further distance.

Abstract: Embodiments of the present disclosure describe drug delivery with a reusable pen injector. In particular, several embodiments are directed to motor-driven delivery of cartridge-based medicaments with an electronic pen injector device and associated pen cap device.

Abstract: Auto-injectors and associated assemblies and methods for delivery of liquid medicament in a controlled manner are disclosed herein.

Abstract: Systems and methods for delivering a dose of a substance to a living being are disclosed. In one implementation, a device includes (i) a contact sensor positioned such that the contact sensor is in contact with an object when the device is in a proper position for delivering a dose of the substance to the object, (ii) a temperature sensor, (iii) a delivery apparatus configured to deliver a dose of the substance to the object after the delivery apparatus is activated, and a transmitter configured to communicate with an external device. The device further includes one or more processors configured to determine, using the contact sensor, whether the contact sensor is in contact with the object and activate the delivery apparatus after determining that the contact sensor is in contact with the object. The delivery apparatus, after being activated, delivers a dose of the substance to the object.

Abstract: An autoinjector device includes a dose cassette having an outer container and a needle cap having a base with a diameter larger than the outer container of the dose cassette. The autoinjector device further include a housing for receiving the dose cassette, a clasp mechanism configured to hold the dose cassette within the housing, and an actuator configured to move the dose cassette proximally within the housing after the dose cassette is secured within the housing. The movement of the dose cassette causes the base of the needle cap to mechanically engage with a distal end of the housing, and the mechanical engagement between the base of the needle cap and the distal end of the housing causes the needle cap to separate from the dose cassette.

Abstract: An autoinjection housing device includes a housing for receiving a dose cassette, a base latch configured to hold the dose cassette within the housing, and a back plate operably connected to a spring. The back plate is configured to move proximally within the housing upon receipt of the dose cassette into the housing, and the proximal movement of the back plate compresses the spring. The autoinjection housing device further includes an actuator operably connected to the base latch. The actuator is configured to move the base latch and the dose cassette proximally within the housing after the dose cassette is secured in the housing. The base latch is configured to move radially outwards upon said proximal movement of the base latch within the housing. The radial movement of the base latch is configured to cause the dose cassette to become unsecured within the housing.

Abstract: A device includes a motor and a hollow drive shaft. The motor is configured to rotate the hollow drive shaft. A lead screw nut is operably connected to the hollow drive shaft. The lead screw nut is configured to rotate upon rotation of the hollow drive shaft. A lead screw is operably connected to the lead screw nut. The lead screw is configured to move within the lead screw nut and the lead screw is configured to pass through at least part of the hollow drive shaft.

Abstract: Auto-injectors and associated assemblies and methods for delivery of liquid medicament in a controlled manner are disclosed herein.

Abstract: Embodiments of the present disclosure describe drug delivery with a reusable pen injector. In particular, several embodiments are directed to motor-driven delivery of cartridge-based medicaments with an electronic pen injector device and associated pen cap device.

Abstract: An in vitro chamber for mimicking the mechanical and electrical forces found in vivo under physiological or pathological state. A chamber provides conditioning stimuli. The conditioning stimuli replicate a pathology, including the ability to replicate a diseased pathology. The chamber is configured to allow the additional stimuli to test physical, chemical or electrical stimuli impact on cells experiencing the particular pathology. Pharmaceuticals may be tested ex-vivo on cells exhibiting a pathology in an environment mimicking the in-vitro environment. Physical components such as pacemakers may also be tested on such cells in the chamber.