Abstract: The present invention relates to cancer diagnostics and therapies and to the detection of alterations in cancer cells that are diagnostic, prognostic or predictive. In particular, the present invention provides a method for detecting and analyzing whether a patient suffering from a cancer is responsive to the treatment with an EGFR inhibitor. In the method, a tissue section from a cancer sample is subjected to assays based on immunohistochemistry and enzymatic metallography.

Abstract: The present invention relates to cancer diagnostics and therapies and to the detection of alterations in cancer cells that are diagnostic, prognostic or predictive. In particular, the present invention provides a method for detecting and analyzing whether a patient suffering from a cancer is responsive to the treatment with an EGFR inhibitor. In the method, a tissue section from a cancer sample is subjected to assays based on immunohistochemistry and enzymatic metallography.

Abstract: A handrest for musical instruments includes a fastening loop attached to the instrument, a handrest handle attached to the fastening loop that shifts the weight of the instrument from the player's thumb to the fold between the player's thumb and index finger, the handrest handle including an upper end for resting on the players fold, a palm portion extending downwardly from the upper end for contacting the player's palm, and a turning joint at a plam point of the lower palm portion, the palm point spaces downwardly from the upper end.

Abstract: The handrest facilitates the supporting of musical instruments and similar objects. When the player supports a musical instrument over long periods of times, the tendon between his thumb and wrist will be susceptible to tenosynovitis and the edge of his thumb will grow a callus. A handrest consisting of the parts (1-6) shown in FIG. 1 shifts the weight of the object to be supported from the thumb to the area between the thumb and the index finger. The control members allow the handrest to be adapted to different hand sizes and playing styles. The use of a handrest allows longer practising periods and more rapid and sensitive fingering.