Patents by Inventor Jaroslava Novotny

Jaroslava Novotny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antigenic preparations and the isolation of such preparations
    Publication number: 20030108572
    Abstract: The present invention provides novel antigenic preparations comprising proteinaceous material associated with adenylate cyclase activity in cultures of B.pertussis, the said preparations being useful as components of acellular whooping cough vaccines. The invention further provides methods for the isolation of such antigenic preparations.
    Type: Application
    Filed: December 27, 2002
    Publication date: June 12, 2003
    Inventors: Pavel Novotny, Jaroslava Novotny, Juan Antonio Montaraz Crespo, Juraj Ivanyi
  • ANTIGENIC PREPARATIONS AND THE ISOLATION OF SUCH PREPARATIONS
    Publication number: 20020150595
    Abstract: The present invention provides novel antigenic preparations comprising proteinaceous material associated with adenylate cyclase activity in cultures of B.pertussis, the said preparations being useful as components of acellular whooping cough vaccines. The invention further provides methods for the isolation of such antigenic preparations.
    Type: Application
    Filed: June 30, 1999
    Publication date: October 17, 2002
    Applicant: MILLEN, WHITE, ZELANO & BRANIGAN, P.C.
    Inventors: PAVEL NOVOTNY, JAROSLAVA NOVOTNY, JUAN ANTONIO MONTARAZ CRESPO, JURAJ IVANYI
  • Antigenic preparations and the isolation of such preparations
    Patent number: 6127151
    Abstract: A method of deriving an antigen from Bordetella pertussis, wherein the antigen is characterized by the following features: a relative molecular weight of about 67,000 to 73,000 as determined by 12%(w/w) polyacrylamide gel electrophoresis and a proline:glutamic acid ratio of about 1:1 as determined by amino acid analysis. The method comprises: (a) culturing Bordetella pertussiscells; (b) treating the culture of (a) to obtain an outer membrane fraction; and (c) isolating the antigen from the outer membrane fraction of (b).
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 3, 2000
    Assignee: Medeva Pharma Limited
    Inventors: Pavel Novotny, deceased, by Jaroslava Novotny, administrator, Juan Antonio Montaraz Crespo, Juraj Ivanyi
  • Antigenic preparations and the isolation of such preparations
    Patent number: 6048700
    Abstract: The invention provides a vaccine containing a proteinaceous material derived from the outer membrane of Bordetella pertussis, wherein the proteinaceous material is characterized by a relative molecular weight of about 67,000 to 73,000, preferably 69,000, as determined by 12% (w/w) polyacrylamide gel electrophoresis and a proline:glutamic acid ratio of about 1:1 as determined by amino acid analysis, in a pharmaceutically acceptable carrier or adjuvant. The invention also provides a method of inducing an immune response in an individual involving administering the vaccine of the invention to an individual.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 11, 2000
    Assignee: Medeva Pharma Limited
    Inventors: Pavel Novotny, Juan Antonio Montaraz Crespo, Juraj Ivanyi, Jaroslava Novotny