Abstract: A sensor module for a lighting fixture includes a module housing configured to be mounted to a lighting fixture, a light sensor mounted in the module housing, and a sensor cover over the light sensor. The sensor cover includes a first surface oriented to face a task surface within an area of interest, and a second surface opposite the first surface. The first surface includes a first Fresnel lens having a number of Fresnel ridges oriented in a first direction. The second surface includes a second Fresnel lens having a number of Fresnel ridges oriented in a second direction, which is different from the first direction. Providing the first Fresnel lens and the second Fresnel lens with differently oriented Fresnel ridges allows the sensor cover to focus light from a relatively large portion of the task surface to the light sensor while remaining small.

Abstract: Emergency lighting devices and methods are disclosed. An emergency lighting device includes a first group of solid state emitters configured to emit light of a first color. The emergency lighting device also includes a second group connected in series to the first group and configured to emit a second color. The groups are configured to receive a normal operation current from an LED driver at the input end of the first group and output the normal operation current at the output end of the second group. In an emergency, the first group receives an emergency operation current from an emergency LED driver at an emergency input and outputs the emergency operation current at an emergency output located.

Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.

Abstract: Articles and methods for preparing a surface for obtaining a patient sample, such as blood, are generally provided. In some embodiments, the methods involve wiping a surface of skin of a patient in preparation for obtaining a sample (e.g., a blood sample) from the patient. In some embodiments, the methods involve wiping the surface of the skin with two or more wipes. For instance, the surface of the skin may be wiped with a first wipe comprising a surfactant and a second wipe comprising an antiseptic solution. Advantageously, the use of a first wipe including a surfactant followed by a second wipe may remove a higher amount of certain contaminants (e.g., proteins, bacteria, viruses) from the surface of the skin as compared to the use of a single wipe or by hand-washing alone.

Abstract: Microfluidic systems including liquid containment regions and methods associated therewith for performing chemical, biological, or biochemical analyzes are provided. Liquid containment regions of a microfluidic device may include regions that capture one or more liquids flowing in the device, while allowing gases or other fluids in the device to pass through the region. This may be achieved, in some embodiments, by positioning one or more absorbent materials in the liquid containment region for absorbing the liquids. This configuration may be useful for removing air bubbles from a stream of fluid and/or for separating hydrophobic liquids from hydrophilic liquids. In certain embodiments, the liquid containment region prevents any liquid from passing through the region. In some such cases, the liquid containment region may act as a waste area by capturing substantially all of the liquid in the device, thereby preventing any liquid from exiting the device.

Abstract: Systems and methods for analysis of samples, and in certain embodiments, microfluidic sample analyzers configured to receive a cassette containing a sample therein to perform an analysis of the sample are described. The microfluidic sample analyzers may be used to control fluid flow, mixing, and sample analysis in a variety of microfluidic systems such as microfluidic point-of-care diagnostic platforms. Advantageously, the microfluidic sample analyzers may be, in some embodiments, inexpensive, reduced in size compared to conventional bench top systems, and simple to use. Cassettes that can operate with the sample analyzers are also described.

Abstract: Articles and methods for collecting and/or facilitating transfer of fluids are generally provided. In some embodiments, an article comprises a fluid collection region for introducing a fluid, such as a sample (e.g., blood sample) or a reagent, into a fluidic system. The articles and methods described herein may be useful for facilitating the filling of relatively small channels with a fluid, such as channels of a microfluidic device. The articles and methods may, for example, interface with a patient sample (e.g., a droplet of blood), or with a macroscopic fluid source such as a pipette or syringe. In certain embodiments, articles and methods described herein may increase the ease of collecting a fluidic sample from a patient, prevent or reduce spillage of the fluidic sample, reduce contamination of a fluidic sample, and/or prevent or reduce air from entering a fluidic sample or device compared to certain existing fluid collection devices.

Abstract: A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample.

Abstract: A solid state lighting apparatus can include a variable color input signal configured to indicate a target color of light output from the apparatus. A string current Pulse Width Modulation (PWM) controller circuit can be coupled to the variable color input signal, where the string current PWM controller circuit can be configured to generate a plurality of PWM signals having respective variable duty cycles to enable/disable respective particular string currents for respective variable times as the variable color input signal changes.

Abstract: The disclosure is directed to storing data in different tiers of a database based on the access pattern of the data. Immutable data, e.g., data that does not change or changes less often than a specified threshold, is stored in a first storage tier of the database, and mutable data, e.g., data that changes more often than immutable data, is stored in a second storage tier of the database. The second storage tier of the database is more performant than the first storage tier, e.g., the second storage tier has a higher write endurance and a lower write latency than the first storage tier. All writes to the database are performed at the second storage tier and reads on both storage tiers. The storage tiers are synchronized, e.g., the set of data is copied from the second to the first storage tier based on a trigger, e.g., a specified schedule.

Abstract: Systems and methods for analysis of samples, and in certain embodiments, microfluidic sample analyzers configured to receive a cassette containing a sample therein to perform an analysis of the sample are described. The microfluidic sample analyzers may be used to control fluid flow, mixing, and sample analysis in a variety of microfluidic systems such as microfluidic point-of-care diagnostic platforms. Advantageously, the microfluidic sample analyzers may be, in some embodiments, inexpensive, reduced in size compared to conventional bench top systems, and simple to use. Cassettes that can operate with the sample analyzers are also described.

Abstract: Fluidic devices and methods associated with mixing of fluids in fluidic devices are provided. In some embodiments, a method may involve the mixing of two or more fluids in a channel segment of a fluidic device. The fluids may be in the form of, for example, at least first, second and third fluid plugs, composed of first, second, and third fluids, respectively. The second fluid may be immiscible with the first and third fluids. In certain embodiments, the fluid plugs may be flowed in series in the channel segment, e.g., in linear order, causing the first and third fluids to mix without the use of active components such as mixers. The mixing of fluids in a channel segment as described herein may allow for improved performance and simplification in the design and operations of fluidic devices that rely on mixing of fluids.

Abstract: The specification generally discloses systems and methods for mixing and delivering fluids in microfluidic systems. The fluids can contain, in some embodiments reagents that can participate in one or more chemical or biological reactions. Some embodiments relate to systems and methods employing one or more vent valves to controllably flow and/or mix portions of fluid within the microfluidic system. Advantageously, fluid control such as a sequence of fluid flow and/or a change in flow rate, can be achieved by opening and closing one or more vent valves and by applying a single source of fluid flow (e.g., a vacuum) operated at a substantially constant pressure. This can simplify the operation and use of the device by an intended user.

Abstract: Fluidic devices and methods including those that provide storage and/or facilitate fluid handling of reagents are provided. Fluidic devices described herein may include channel segments positioned on two sides of an article, optionally connected by an intervening channel passing through the article. The channel segments may be used to store reagents in the device prior to first use by an end user. The stored reagents may include fluid plugs positioned in linear order so that during use, as fluids flow to a reaction site, they are delivered in a predetermined sequence. The specific geometries of the channel segments and the positions of the channel segments within the fluidic devices described herein may allow fluid reagents to be stored for extended periods of time without mixing, even during routine handling of the devices such as during shipping of the devices, and when the devices are subjected to physical shock or vibration.

Abstract: Systems and methods for analysis of samples, and in certain embodiments, microfluidic sample analyzers configured to receive a cassette containing a sample therein to perform an analysis of the sample are described. The microfluidic sample analyzers may be used to control fluid flow, mixing, and sample analysis in a variety of microfluidic systems such as microfluidic point-of-care diagnostic platforms. Advantageously, the microfluidic sample analyzers may be, in some embodiments, inexpensive, reduced in size compared to conventional bench top systems, and simple to use. Cassettes that can operate with the sample analyzers are also described.

Abstract: Systems and methods for optical communication using single source optical transmission are disclosed. A representative method includes receiving optical signals at a first frequency by a receiver (RX) from an optical fiber. The received optical signals are routed to a modulator that modulates the optical signals at a second frequency. The optical signals are emitted by a transmitter (TX) back to the optical fiber at the second frequency.

Abstract: Optical communication using optical resonators with noise margins is disclosed. A representative system includes an optical fiber for transmitting optical signals, a receiver configured to receive the optical signals, and a plurality of optical resonators optically connecting the optical fiber to the receiver. The individual optical resonators can have peak sensitivities at mutually different wavelengths of light. In some embodiments the optical resonators can be Q-switches.

Abstract: Fluidic devices and methods associated with mixing of fluids in fluidic devices are provided. In some embodiments, a method may involve the mixing of two or more fluids in a channel segment of a fluidic device. The fluids may be in the form of, for example, at least first, second and third fluid plugs, composed of first, second, and third fluids, respectively. The second fluid may be immiscible with the first and third fluids. In certain embodiments, the fluid plugs may be flowed in series in the channel segment, e.g., in linear order, causing the first and third fluids to mix without the use of active to components such as mixers. The mixing of fluids in a channel segment as described herein may allow for improved performance and simplification in the design and operations of fluidic devices that rely on mixing of fluids.

Abstract: An optical waveguide body includes first and second pluralities of light extraction features disposed on a first side of the waveguide body and adapted to direct light out of the waveguide body through a second side of the waveguide body opposite the first side. Each of the first plurality of light extraction features has a linear shape and each of the second plurality of light extraction features has at least one of a piecewise linear shape and a nonlinear shape. The piecewise linear shape comprises two adjacent planar surfaces with an angle therebetween of at least about 30 and at most about 180 degrees. The waveguide body further has a light coupling cavity.