Patents by Inventor Jason Dyck

Jason Dyck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THE USE OF EMPAGLIFLOZIN FOR THE TREATMENT OF ULCERATIVE COLITIS AND CROHN'S DISEASE
    Publication number: 20240148767
    Abstract: A use of empagliflozin for the treatment of ulcerative colitis and Crohn's disease.
    Type: Application
    Filed: March 3, 2022
    Publication date: May 9, 2024
    Inventors: Jason DYCK, Karen Lynn MADSEN
  • Malonyl-CoA Decarboxylase Inhibitors Useful as Metabolic Modulators
    Publication number: 20080070869
    Abstract: The present invention relates to novel compounds (I), their prodrugs, and the pharmaceutically acceptable salts as well as pharmaceutical compositions containing such compounds useful in treating certain metabolic diseases and diseases modulated by the inhibition of the enzyme malonyl-coenzyme A decarboxylase (malonyl-CoA decarboxylase, MCD). In particular, the invention relates to compounds and compositions and the methods for the prophylaxis, management and treatment of cardiovascular diseases, diabetes, acidosis, cancers, and obesity through the inhibition of malonyl-coenzyme A decarboxylase.
    Type: Application
    Filed: September 14, 2007
    Publication date: March 20, 2008
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Thomas Arrhenius, Mi Chen, Jie Fei Cheng, Yujin Huang, Alex Nadzan, Sovouthy Tith, David Wallace, Bin Liu, Masahiro Nishimoto, Gary Lopaschuk, Jason Dyck
  • Compounds that stimulate glucose utilization and methods of use
    Publication number: 20060205811
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, i and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
    Type: Application
    Filed: May 18, 2006
    Publication date: September 14, 2006
    Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Gary Lopaschuk, John Vederas, Jason Dyck
  • Compounds that stimulate glucose utilization and methods of use
    Publication number: 20060173208
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, i and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
    Type: Application
    Filed: March 6, 2006
    Publication date: August 3, 2006
    Applicant: The Governors of the University of Alberta
    Inventors: Gary Lopaschuk, John Vederas, Jason Dyck
  • Compounds that stimulate glucose utilization and methods of use
    Publication number: 20050182133
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, I, m and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
    Type: Application
    Filed: February 23, 2005
    Publication date: August 18, 2005
    Applicant: University of Alberta
    Inventors: Gary Lopaschuk, John Vederas, Jason Dyck
  • Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors
    Publication number: 20050032828
    Abstract: The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.
    Type: Application
    Filed: July 28, 2004
    Publication date: February 10, 2005
    Inventors: Jie Cheng, Mi Chen, Thomas Arrhenius, Mark Wilson, Gary Lopaschuk, Jason Dyck, Rossy Serafimov
  • Cyanoguanidine-based azole compounds useful as malonyl-CoA decarboxylase inhibitors
    Publication number: 20050032824
    Abstract: The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.
    Type: Application
    Filed: July 28, 2004
    Publication date: February 10, 2005
    Inventors: Jie Cheng, Bin Liu, Thomas Arrhenius, Mark Wilson, Alex Nadzan, Gary Lopaschuk, Jason Dyck, Rossy Serafimov
  • Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors
    Publication number: 20050026969
    Abstract: The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.
    Type: Application
    Filed: July 28, 2004
    Publication date: February 3, 2005
    Inventors: Jie Cheng, Bao Nguyen, Xuewei Liu, Gary Lopaschuk, Jason Dyck
  • Cyanoamide compounds useful as malonyl-CoA decarboxylase inhibitors
    Publication number: 20050026945
    Abstract: The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.
    Type: Application
    Filed: July 28, 2004
    Publication date: February 3, 2005
    Inventors: Mark Kafka, Mark Wilson, Anna Russell, Gary Lopaschuk, Jason Dyck