Patents by Inventor Jason K. Myers

Jason K. Myers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Positive allosteric modulators of the nicotinic acetylcholine receptor
    Publication number: 20080132551
    Abstract: The invention provides compounds of Formula I: wherein A, B, and X are described herein. These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which ?7 nAChR is known to be involved.
    Type: Application
    Filed: March 24, 2004
    Publication date: June 5, 2008
    Inventors: Bruce Nelsen Rogers, David Walter Piotrowski, Brandon J. Margolis, Jason K. Myers, Vincent Edward Groppi, Daniel G. Rudmann
  • Azabicyclic compounds for the treatment of disease
    Patent number: 7001900
    Abstract: The invention provides compounds of Formula I: wherein Azabicyclo is W is a six-membered heterocyclic ring system having 1–2 nitrogen atoms or a 10-membered bicyclic-six-six-fused-ring system having up to two nitrogen atoms within either or both rings, provided that no nitrogen is at a bridge of the bicyclic-six-six-fused-ring system, and further having 1–2 substitutents independently selected from R3. These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals to treat diseases or conditions in which ?7 is known to be involved.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: February 21, 2006
    Assignee: Pfizer Inc.
    Inventors: Eric Jon Jacobsen, Jason K. Myers, Daniel Patrick Walker, Donn G. Wishka, Steven Charles Reitz, David W. Piotrowski, Brad A. Acker, Vincent E. Groppi, Jr.
  • Azabicyclic-substituted-heteroaryl compounds for the treatment of disease
    Patent number: 6919359
    Abstract: The invention provides compounds of Formula I: Azabicyclo-N(R1)—C(?X)—W??Formula I These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which ?7 is known to be involved.
    Type: Grant
    Filed: November 6, 2002
    Date of Patent: July 19, 2005
    Assignee: Pfizer Inc
    Inventors: David W. Piotrowski, Jason K. Myers, Bruce N. Rogers, Eric Jon Jacobsen, Alice L. Bodnar, Vincent E. Groppi, Jr., Daniel Patrick Walker, Brad A. Acker
  • Substituted azabicyclic moieties for the treatment of disease
    Patent number: 6869946
    Abstract: The invention provides compounds of Formula I: wherein m1 is 0 or 1; m2 is 1 or 2; R1 is —H, alkyl, halogenated alkyl, substituted alkyl, cycloalkyl, or phenyl; R2 is —H, alkyl, halogenated alkyl, substituted alkyl, cycloalkyl, or phenyl, provided that when m1 is 1 at least one of R1 and R2 is —H; or a pharmaceutically acceptable salt, pharmaceutical composition, a pure enantiomer or racemic mixture thereof. The invention also provides a method for treating a disease or condition in a mammal, wherein the ?7 nicotinic acetylcholine receptor is implicated and for treating diseases where there is a sensory-gating deficit in a mammal comprising administering to a mammal a therapeutically effective amount of a compound of Formula I. These compounds may be in the form of pharmaceutical salts or compositions, and may be in pure enantiomeric form or may be racemic mixtures.
    Type: Grant
    Filed: April 17, 2002
    Date of Patent: March 22, 2005
    Assignee: Pfizer Inc
    Inventors: Eric Jon Jacobsen, Daniel Patrick Walker, Jason K. Myers, David W. Piotrowski, Vincent E. Groppi, Jr.
  • Substituted-aryl compounds for treatment of disease
    Patent number: 6852716
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals to treat diseases or conditions in which ?7 is known to be involved.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: February 8, 2005
    Assignee: Pfizer Inc
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Jason K. Myers, Vincent E. Groppi, Jr.
  • Substituted-aryl compounds for treatment of disease
    Publication number: 20030236279
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 10, 2003
    Publication date: December 25, 2003
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Jason K. Myers, Vincent E. Groppi
  • Azabicyclic compounds for the treatment of disease
    Publication number: 20030236270
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 14, 2003
    Publication date: December 25, 2003
    Inventors: Eric Jon Jacobsen, Jason K. Myers, Daniel Patrick Walker, Donn G. Wishka, Steven Charles Reitz, David W. Piotrowski, Brad A. Acker, Vincent E. Groppi
  • Azabicyclic-substituted-heteroaryl compounds for the treatment of disease
    Publication number: 20030207913
    Abstract: The invention provides compounds of Formula I:
    Type: Application
    Filed: November 6, 2002
    Publication date: November 6, 2003
    Inventors: David W. Piotrowski, Jason K. Myers, Bruce N. Rogers, Eric Jon Jacobsen, Alice L. Bodnar, Vincent E. Groppi, Daniel Patrick Walker, Brad A. Acker
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Patent number: 6599916
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: July 29, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi, Jr., David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Substituted-heteroaryl-7-aza[2.2.1]bicycloheptanes for the treatment of disease
    Patent number: 6562816
    Abstract: The invention provides compounds of Formula I: compounds of the Formula I: wherein R1, R2, R4, R6, X, and W are defined herein. These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 14, 2002
    Date of Patent: May 13, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Donn G. Wishka, Jason K. Myers, Bruce N. Rogers, Eric Jon Jacobsen, David W. Piotrowski, Jeffrey W. Corbett, Alice L. Bodnar, Vincent E. Groppi, Jr.
  • SUBSTITUTED-HETEROARYL-7-AZA[2.2.1] BYCYCLOHEPTANES FOR THE TREATMENT OF DESEASE
    Publication number: 20030069290
    Abstract: The invention provides compounds of Formula I: compounds of the Formula I: 1
    Type: Application
    Filed: August 14, 2002
    Publication date: April 10, 2003
    Inventors: Donn G. Wishka, Jason K. Myers, Bruce N. Rogers, Eric Jon Jacobsen, David W. Piotrowski, Jeffrey W. Corbett, Alice L. Bodnar, Vincent E. Groppi,
  • Substituted-aryl 7-aza[2.2.1]bicycloheptanes for the treatment of disease
    Publication number: 20030069296
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: August 14, 2002
    Publication date: April 10, 2003
    Inventors: Donn G. Wishka, Jason K. Myers, Vincent E. Groppi
  • Substituted azabicyclic moieties for the treatment of disease
    Publication number: 20030055043
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: April 17, 2002
    Publication date: March 20, 2003
    Inventors: Eric Jon Jacobsen, Daniel Patrick Walker, Jason K. Myers, David W. Piotrowski, Vincent E. Groppi
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Patent number: 6500840
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: December 31, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi, Jr., David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Patent number: 6492385
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: December 10, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi, Jr., David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Quinuclidine-substituted aryl compounds for treatment of disease
    Patent number: 6492386
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: December 10, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jason K. Myers, Vincent E. Groppi, Jr., David W. Piotrowski
  • Quinuclidine-substituted aryl compounds for treatment of disease
    Patent number: 6486172
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: November 26, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jason K. Myers, Vincent E. Groppi, Jr., David W. Piotrowski
  • Quinuclidine-substituted aryl compounds for treatment of disease
    Patent number: 6479510
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtures or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: November 12, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jason K. Myers, Vincent E. Groppi, Jr., David W. Piotrowski
  • Quinuclidine-substituted heteroaryl moieties for treatment of disease
    Publication number: 20020091135
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: August 17, 2001
    Publication date: July 11, 2002
    Inventors: Jason K. Myers, Bruce N. Rogers, Vincent E. Groppi,, David W. Piotrowski, Alice L. Bodnar, Eric Jon Jacobsen, Jeffrey W. Corbett
  • Quinuclidine-substituted aryl compounds for treatment of disease
    Publication number: 20020052389
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: August 17, 2001
    Publication date: May 2, 2002
    Inventors: Jason K. Myers, Vincent E. Groppi, David W. Piotrowski