Abstract: Disclosed herein is a system for delivering a nitric oxide to a subject, wherein the system comprises: (a) a nitric oxide injection line configured to inject a first gas at an injection point into a breathing conduit comprising a breathing gas, wherein the first gas comprises a first amount of nitric oxide; (b) a sampling line configured to sample a second gas comprising a second amount of nitric oxide and the breathing gas at a sampling location between the injection point of the first gas and a subject and (c) a feedback-loop controller that is in communication with: (i) a nitric oxide set-point controller configured to set a nitric oxide set-point amount; (ii) a source configured to provide a third gas having a third amount of nitric oxide; and (iii) at least one sensor configured to measure the second amount of nitric oxide in the sampling line.

Abstract: The present invention is related to manufacturing surfaces with an axis decentered from the spindle axis. In particular, the present invention is related to compensating for tool geometry in cutting processes that involve an oscillating tool.

Abstract: The present invention provides a contact lens having an orientation/stabilization and optionally translation feature that does not provide an prism optical distortion and can effectively maintain a predetermined orientation of the lens on an eye. Like a conventional lens ballast, the orientation feature of the invention works by weighing the lens at its lower half portion, causing it to come to an equilibrium position on the eye. With such orientation feature, the optical zone of the anterior surface can be designed independently to provide an optimal visual performance.

Abstract: The present invention is related to a method for designing and making a contact lens which comprises stiffening rib features that provide even distribution of pressure from the lens over the cornea of an eye and/or allows the lens structure to maintain balance of forces for consistent and correct lens orientation on an eye during lens translation or eye lid movement. The invention also provides a soft contact lens comprising stiffening rib features that provides localized directional reinforcements to the lens structure to evenly distribute pressure from the lens over the cornea of an eye and/or to maintain balance of forces for consistent and correct lens orientation on an eye during lens translation or eye lid movement.

Abstract: The present invention provides a contact lens having an orientation/stabilization and optionally translation feature that does not provide an prism optical distortion and can effectively maintain a predetermined orientation of the lens on an eye. Like a conventional lens ballast, the orientation feature of the invention works by weighing the lens at its lower half portion, causing it to come to an equilibrium position on the eye. With such orientation feature, the optical zone of the anterior surface can be designed independently to provide an optimal visual performance.