Abstract: This invention concerns novel imidazo[1,2-b]-pyridazines and their use as agents for treating anxiety.

Abstract: A compound of the formula: ##STR1## wherein R.sub.1 is 3-pyridyl or 4-pyridyl; and R.sub.2 is hydrogen or lower alkyl (C.sub.1 -C.sub.3); or a nontoxic pharmaceutically acceptable salt thereof.

Abstract: This disclosure describes novel substituted 1,2,4-triazolo[4,3-a]pyridines which possess anxioltic activity.

Abstract: Aryl and heteroaryl[7-(aryl and heteroaryl)pyrazolo[1,5-a]pyrimidin-3-yl]methanones which are new compounds active as anxiolytic, anticonvulsant, sedative-hypnotic and skeletal muscle relaxant agents in mammals and the novel process of making these compounds.

Abstract: Substituted phenyl-1,2,4-triazolo[4,3-b]pyridazin-3(2H)-ones, useful as anti-asthma agents.

Abstract: This disclosure describes 7-heteroaryl[1,2,4]triazolo[1,5-a]pyrimidines which are useful as anxiolytic agents.

Abstract: Novel compounds are described having the formula ##STR1## wherein Z is ##STR2## R.sub.1 is hydrogen or a C.sub.1 -C.sub.4 lower alkyl; R.sub.2 is hydrogen, a C.sub.1 -C.sub.4 lower alkyl, hydroxy-R.sub.8 -, lower alkyl-R.sub.8 -, mercapto-R.sub.8 -, cyclohexyl, cyclopentyl, phenyl, phenyl-R.sub.8 -, indolyl-R.sub.8 -, carboxy-R.sub.8 -, amino-R.sub.8 - or carbamoyl-R.sub.8 -, wherein R.sub.8 - is a divalent C.sub.1 -C.sub.6 straight chain parafinic moiety; R.sub.3 is hydrogen or C.sub.1 -C.sub.4 lower alkyl; R.sub.4 is hydrogen, lower alkanoyl, benzoyl or phenyl-substituted-lower alkanoyl; R.sub.5 is hydrogen or a C.sub.1 -C.sub.4 lower alkyl; R.sub.1, R.sub.2 and R.sub.5 excluding tertiary butyl; ARYL is 1-naphthyl, 2-naphthyl, 4-chloro-1-naphthyl, 4-methoxy-1-naphthyl, 5,6,7,8-tetrahydro-1-naphthyl, 5,6,7,8-tetrahydro-2-naphthyl, 4-biphenylyl, 5-indanyl, 4-indanyl, phenyl, or substituted phenyl moieties having the formula ##STR3## wherein R.sub.

Abstract: This disclosure describes novel substituted phenyl-5-aminopyrazoles useful as anxiolytic and/or anti-depressant agents.

Abstract: Novel pyrimidine compounds are disclosed of the class represented by the formula: ##STR1## wherein R.sub.1 is selected from the class consisting essentially of hydrogen, chloro, bromo, cyano (--CN), carbamoyl (--CO--NH.sub.2), carboxyl (--COOH), and lower alkoxycarbonyl (--CO--O--R.sub.3, where R.sub.3 is a lower alkyl radical having 1-4 carbon atoms), and wherein R.sub.2 is a monovalent radical selected from the class consisting essentially of furyl, thienyl, 3-pyridyl and 3-pyridyl-N-oxide, either of said pyridyl radicals optionally being substituted with an alkyl radical having from 1 to 4 carbon atoms. Processes of preparing such compounds are disclosed.The novel compounds are useful as anxiolytic agents in ameliorating anxiety in a mammal.

Abstract: This disclosure describes novel [4R]-3-(.omega.-aroylpropionyl)-4-thiazolidinecarboxylic acids and esters and the cationic salts thereof which are useful as hypotensive agents in mammals.

Abstract: Novel para-[aryl(alkyl or alkenyl)amino]benzoic acids, esters, pharmaceutically acceptable salts and pharmaceutical compositions thereof and a method of lowering serum lipid levels in mammals therewith.

Abstract: This disclosure describes novel substituted .omega.-heteroaroyl(propionyl or butyryl)-L-prolines and the esters and cationic salts thereof which are useful as hypotensive agents in mammals.

Abstract: This disclosure describes novel substituted .omega.-heteroaroyl(propionyl or butyryl)-L-prolines and the esters and cationic salts thereof which are useful as hypotensive agents in mammals.

Abstract: This disclosure describes novel substituted .omega.-heteroaroyl(propionyl or butyryl)-L-prolines and the esters and cationic salts thereof which are useful as hypotensive agents in mammals.

Abstract: This disclosure describes novel substituted .omega.-heteroaroyl(propionyl or butyryl)-L-prolines and the esters and cationic salts thereof which are useful as hypotensive agents in mammals.

Abstract: A method of treating asthma in a warm-blooded animal using the compound 6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3(2H)-one.

Abstract: This disclosure describes substituted pyrazolo[1,5-a]pyrimidines which possess anxiolytic activity.

Abstract: This disclosure describes pharmaceutical compositions having hypolipidemic and/or hypoglycemic activity which contain a substituted naphthyloxyalkylaminobenzoic acid or salt or ester thereof.

Abstract: This disclosure describes novel 6-phenyl and substituted 6-phenyl-1,2,4-triazolo[4,3-b]pyridazines and their use as anxiolytic agents.

Abstract: This disclosure describes novel 6- and 8-heteroaryl and substituted 6- and 8-heteroaryl-1,2,4-triazolo[4,3-b]-pyridazines and their use as agents for treating anxiety.