Patents by Inventor Jay F. Kunzler

Jay F. Kunzler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High refractive-index, hydrophilic monomers and polymers, and ophthalmic devices comprising such polymers
    Patent number: 7781496
    Abstract: An intraocular lens comprising a polymer that is prepared from a monomer mixture comprising a monomer of formula G-D-Ar??(I) wherein Ar is a C6-C24 aromatic group having a hydrophilic substituent, D is a divalent linking group, and G is a reactive functional group selected from the group consisting of acryloyl, acryloyloxy, methacryloyl, methacryloyloxy and mercapto. The polymer has an equilibrium water content of greater than 4.5 percent by weight.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: August 24, 2010
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark
  • Use of silylated sulfonate monomers to improve contact lens wettability
    Patent number: 7732546
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain hydrophilic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. The polymeric compositions comprise polymerizable hydrophilic siloxanyl monomers.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: June 8, 2010
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler
  • METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES
    Publication number: 20100118261
    Abstract: Novel polymers for biomedical use, especially rigid gas permeable contact lenses that are based on bulky side-chain siloxane cross linkers. The siloxanes, either alone, or as copolymers with bulky and non-bulky mono-functional polymerizable siloxanes, fluoro monomers, such as hexafluoroisopropyl methacrylate, and hydrophilic monomers, result in transparent, high oxygen permeable polymers possessing excellent lathing and milling characteristics.
    Type: Application
    Filed: November 10, 2008
    Publication date: May 13, 2010
    Inventors: Joseph A. McGee, Jay F. Kunzler, Richard M. Ozark, Joseph C. Salamone
  • LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS
    Publication number: 20100069522
    Abstract: This invention describes the use of amphiphilic multiblock copolymers comprising a hydrophobic segment and a hydrophilic the amphiphilic multiblock copolymer has at least one thio carbonyl thio group capable of participating in a free radical reaction as comonomers in forming ophthalmic devices such as contact lenses, intraocular lenses, corneal implants, etc.
    Type: Application
    Filed: March 16, 2009
    Publication date: March 18, 2010
    Inventors: Jeffrey G. Linhardt, Devon A. Shipp, Jay F. Kunzler, Drazen Pavlovic
  • SILICONE CONTACT LENSES WITH WRINKLED SURFACE
    Publication number: 20100039613
    Abstract: At least one of the surfaces of a silicone contact lens is a wrinkled surface, providing the contact lens surface with a desired topography. The wrinkled surface may include random ridges, either over the entire surface of the lens, or in a desired pattern on the surface of the lens.
    Type: Application
    Filed: October 19, 2009
    Publication date: February 18, 2010
    Applicant: BAUSCH & LOMB INCORPORATED
    Inventors: Ravi Sharma, Robert M. Braun, Daniel M. Ammon, JR., Jay F. Kunzler, Yu-Chin Lai
  • High refractive-index, hydrophilic, arylsiloxy-containing monomers and polymers, and ophthalmic devices comprising such polymers
    Patent number: 7632904
    Abstract: Hydrophilic, arylsiloxy-containing monomers and macromonomers have at least a terminal hydrophilic group attached to an arylsiloxy group. The aryl groups attached to siloxy groups can be substituted with other hydrophilic groups. Polymers comprising such hydrophilic, arylsiloxy-containing monomers and macromonomers avoid or reduce the risk of forming vacuoles of absorbed water. Furthermore, such polymers have high refractive index, and, thus, are advantageously used for making ophthalmic devices, such as intraocular lenses, contact lenses, corneal rings, corneal inlays, and keratoprostheses.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: December 15, 2009
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark
  • Polymeric Materials for Use as Photoablatable Inlays
    Publication number: 20090299348
    Abstract: Photoablatable cornea inlays manufactured from a copolymer of hydrophilic monomer to provide a hydrated material with a refractive index of 1.30 or greater, and a water content from 65% to 90% by weight. The cornea inlay is shaped in the form of a disc or lenticule for placement in the corneal bed of an eye.
    Type: Application
    Filed: June 30, 2009
    Publication date: December 3, 2009
    Inventors: Dominic V. Ruscio, Jay F. Kunzler, Laurent G. Hoffmann
  • Silicone contact lenses with wrinkled surface
    Patent number: 7625598
    Abstract: At least one of the surfaces of a silicone contact lens is a wrinkled surface, providing the contact lens surface with a desired topography. The wrinkled surface may include random ridges, either over the entire surface of the lens, or in a desired pattern on the surface of the lens.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: December 1, 2009
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ravi Sharma, Robert M. Braun, Daniel M. Ammon, Jr., Jay F. Kunzler, Yu-Chin Lai
  • Drug delivery systems based on catonic siloxanyl macromonomers
    Publication number: 20090274745
    Abstract: Matrix controlled diffusion drug delivery systems based on one or more silicon-containing monomers of the general formula: wherein L, X?, n, R1, R2, R3, R4, R5, R6, R7 and V are as set forth herein.
    Type: Application
    Filed: July 8, 2009
    Publication date: November 5, 2009
    Applicant: Bausch & Lomb Incorporated
    Inventors: Jay F. Kunzler, Derek Schorzman, Daniel M. Ammon, JR.
  • Drug delivery system based on cationic siloxanyl macromonomers
    Publication number: 20090274744
    Abstract: Matrix controlled diffusion drug delivery systems are described herein which are based on one or more silicon-containing monomers of the general formula: wherein L, X?, n, R1, R2, R3, R4, R5, R6, R7 and V are as set forth herein.
    Type: Application
    Filed: July 8, 2009
    Publication date: November 5, 2009
    Applicant: Bausch & Lomb Incorporated
    Inventors: Jay F. Kunzler, Derek Schorzman, Daniel M. Ammon, JR.
  • Drug delivery systems based on degradable cationic siloxanyl macromonomers
    Patent number: 7579021
    Abstract: Matrix controlled diffusion drug delivery systems based on one or more silicon-containing monomers of the general formula: wherein L, X?, n, R1, R2, R3, R4, R5, R6, R7 and V are as set forth herein.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: August 25, 2009
    Assignee: Bausch & Lomb Incorporated
    Inventors: Jay F. Kunzler, Derek Schorzman, Daniel M. Ammon, Jr.
  • Gas-permeable materials and medical devices
    Patent number: 7576159
    Abstract: Gas-permeable polymeric materials comprise poly(disubstituted acetylene) and a siloxanyl-based polymer. Medical devices, such as ophthalmic devices, are manufactured from such gas-permeable materials.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: August 18, 2009
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler
  • HIGH WATER CONTENT OPHTHALMIC DEVICES
    Publication number: 20090191256
    Abstract: An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent, wherein the ophthalmic device has an equilibrium water content of at least about 70 weight percent and further wherein the ophthalmic device has an evaporative dehydration barrier layer on the surface thereof. A method for the mitigation of evaporative corneal dehydration employing the high water content ophthalmic device is also disclosed.
    Type: Application
    Filed: January 8, 2009
    Publication date: July 30, 2009
    Inventors: Richard I. Blackwell, Joseph C. Salamone, Jay F. Kunzler
  • MULTI-ARMED MACROMONOMERS
    Publication number: 20090192275
    Abstract: Multi-armed macromonomers containing multiple side chains attached to a siloxy-containing core terminated on each end with one or more first substantially linear polysiloxane radicals having a polymerizable ethylenically unsaturated-containing terminal group, wherein each side chain comprises a second substantially linear polysiloxane radical having a polymerizable ethylenically unsaturated-containing terminal group are disclosed. Biomedical devices such as contact lenses formed from the multi-armed macromonomers are also disclosed.
    Type: Application
    Filed: January 13, 2009
    Publication date: July 30, 2009
    Inventors: Joseph C. Salamone, Jay F. Kunzler
  • Packaging Solutions
    Publication number: 20090173044
    Abstract: Packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear are disclosed. A packaging system includes an ophthalmic device stored in an aqueous packaging solution comprising a substantially water-soluble silicone-containing surfactant. Such solutions are retained on the surface of an unused lens for extended periods of time, resulting in surface modification that persists in the eye, which may provide significant improvement in the wetting properties of fresh contact lenses used for the first time and, moreover, even several hours after lens insertion, preventing dryness and improving lubricity.
    Type: Application
    Filed: October 27, 2008
    Publication date: July 9, 2009
    Inventors: Jeffrey G. Linhardt, Jay F. Kunzler
  • COATING SOLUTIONS COMPRISING SEGMENTED REACTIVE BLOCK COPOLYMERS
    Publication number: 20090171459
    Abstract: This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of reactive segmented block copolymers to the surface of the substrate by means of reactive functionalities of the terminal functionalized surfactant material reacting with complementary surface reactive functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
    Type: Application
    Filed: December 15, 2008
    Publication date: July 2, 2009
    Inventors: Jeffrey G. Linhardt, Devon A. Shipp, Jay F. Kunzler
  • SURFACE ACTIVE SEGMENTED BLOCK COPOLYMERS
    Publication number: 20090171050
    Abstract: This invention is directed toward surface active segmented block copolymers useful to treat the surface of a substrate by means of surface active functionalities of the surface active segmented block copolymer material binding with complementary surface functionalities of the polymer substrate.
    Type: Application
    Filed: December 16, 2008
    Publication date: July 2, 2009
    Inventors: Jeffrey G. Linhardt, Devon A. Shipp, Jay F. Kunzler
  • SEGMENTED INTERACTIVE BLOCK COPOLYMERS
    Publication number: 20090171027
    Abstract: This invention is directed toward interactive segmented block copolymers useful to treat the surface of a substrate by means of interactive functionalities of the interactive segmented block copolymer material binding with complementary surface functionalities of the polymer substrate.
    Type: Application
    Filed: December 15, 2008
    Publication date: July 2, 2009
    Inventors: Jeffrey G. Linhardt, Devon A. Shipp, Jay F. Kunzler, David Vanderbilt
  • COATING SOLUTIONS COMPRISING SEGMENTED INTERACTIVE BLOCK COPOLYMERS
    Publication number: 20090168012
    Abstract: This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of interactive segmented block copolymers to the surface of the substrate by means of interactive functionalities of the segmented block copolymer reacting with complementary surface functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
    Type: Application
    Filed: December 15, 2008
    Publication date: July 2, 2009
    Inventors: Jeffrey G. Linhardt, Devon A. Shipp, Jay F. Kunzler, David Paul Vanderbilt
  • SEGMENTED REACTIVE BLOCK COPOLYMERS
    Publication number: 20090171049
    Abstract: This invention is directed toward reactive segmented block copolymers useful to treat the surface of a substrate by means of reactive functionalities of the reactive segmented block copolymer material reacting with complementary surface reactive functionalities of the polymer substrate.
    Type: Application
    Filed: December 12, 2008
    Publication date: July 2, 2009
    Inventors: Jeffrey G. Linhardt, Devon A. Shipp, Jay F. Kunzler