Patents by Inventor Jay H. Shaw

Jay H. Shaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Two-step hybridization and capture of a polynucleotide
    Patent number: 6534273
    Abstract: A method for capturing a target polynucleotide in a sample onto a solid support with an attached immobilized probe by using a capture probe and two different hybridization conditions that control the order of hybridization, where the first hybridization condition allows hybridization of the capture probe to the target polynucleotide, and the second hybridization condition allows hybridization of the capture probe to the immobilized probe. The method further includes amplifying the captured target polynucleotide by hybridizing at least one primer oligonucleotide to the target polynucleotide and using nucleic acid amplification that initiates from the primer oligonucleotide.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: March 18, 2003
    Assignee: Gen-Probe Incorporated
    Inventors: William G. Weisburg, Jay H. Shaw, Michael M. Becker, Mehrdad R. Majlessi, Steven T. Brentano, Kiyotada Nunomura
  • Two-step hybridization and capture of a polynucleotide
    Publication number: 20020127569
    Abstract: A method for capturing a target polynucleotide in a sample onto a solid support with an attached immobilized probe by using a capture probe and two different hybridization conditions that control the order of hybridization, where the first hybridization condition allows hybridization of the capture probe to the target polynucleotide, and the second hybridization condition allows hybridization of the capture probe to the immobilized probe. The method further includes amplifying the captured target polynucleotide by hybridizing at least one primer oligonucleotide to the target polynucleotide and using nucleic acid amplification that initiates from the primer oligonucleotide.
    Type: Application
    Filed: September 18, 2001
    Publication date: September 12, 2002
    Inventors: William G. Weisburg, Jay H. Shaw, Michael M. Becker, Mehrdad R. Majlessi, Steven T. Brentano, Kiyotada Nunomura
  • Two-step hybridization and capture of a polynucleotide
    Publication number: 20020028459
    Abstract: A method for capturing a target polynucleotide in a sample onto a solid support with an attached immobilized probe by using a capture probe and two different hybridization conditions, which preferably differ in temperature only, is disclosed. The two hybridization conditions control the order of hybridization, where the first hybridization conditions allow hybridization of the capture probe to the target polynucleotide, and the second hybridization conditions allow hybridization of the capture probe to the immobilized probe. The method may be used to detect the presence of a target polynucleotide in a sample by detecting the captured target polynucleotide or amplified target polynucleotide.
    Type: Application
    Filed: July 20, 2001
    Publication date: March 7, 2002
    Inventors: William G. Weisburg, Jay H. Shaw, Michael M. Becker, Mehrdad Majlessi
  • Two-step hybridization and capture of a polynucleotide
    Patent number: 6280952
    Abstract: A method for capturing a target polynucleotide in a sample onto a solid support with an attached immobilized probe by using a capture probe and two different hybridization conditions, which preferably differ in temperature only, is disclosed. The two hybridization conditions control the order of hybridization, where the first hybridization conditions allow hybridization of the capture probe to the target polynucleotide, and the second hybridization conditions allow hybridization of the capture probe to the immobilized probe. The method may be used to detect the presence of a target polynucleotide in a sample by detecting the captured target polynucleotide or amplified target polynucleotide.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: August 28, 2001
    Assignee: Gen-Probe Incorporated
    Inventors: William G. Weisburg, Jay H. Shaw, Michael M. Becker, Mehrdad Majlessi
  • Two-step hybridization and capture of a polynucleotide
    Patent number: 6110678
    Abstract: A method for capturing a target polynucleotide in a sample onto a solid support with an attached immobilized probe by using a capture probe and two different hybridization conditions, which preferably differ in temperature only, is disclosed. The two hybridization conditions control the order of hybridization, where the first hybridization conditions allow hybridization of the capture probe to the target polynucleotide, and the second hybridization conditions allow hybridization of the capture probe to the immobilized probe. The method may be used to detect the presence of a target polynucleotide in a sample by detecting the captured target polynucleotide or amplified target polynucleotide.
    Type: Grant
    Filed: May 1, 1998
    Date of Patent: August 29, 2000
    Assignee: Gen-Probe Incorporated
    Inventors: William G. Weisburg, Jay H. Shaw, Michael M. Becker, Mehrdad Majlessi