Patents by Inventor Jay P. Smith

Jay P. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEM AND METHOD FOR GENERATING A 2D IMAGE USING MAMMOGRAPHY AND/OR TOMOSYNTHESIS IMAGE DATA
    Publication number: 20240169958
    Abstract: The invention includes a method including the steps of obtaining a plurality of images, each of the images in the plurality having at least one corresponding region, generating a merged image, the merged image also having the corresponding region. The step of generating includes selecting an image source from the plurality of images to source image data for the corresponding region in the merged image by comparing attributes of the corresponding regions of the plurality of images to identify the image source having preferred attributes.
    Type: Application
    Filed: October 24, 2023
    Publication date: May 23, 2024
    Applicant: Hologic, Inc.
    Inventors: Kevin Kreeger, Andrew P. Smith, Ashwini Kshirsagar, Jun Ge, Xiangwei Zhang, Haili Chui, Christopher Ruth, Yiheng Zhang, Liyang Wei, Jay Stein
  • KRas G12D inhibitors
    Patent number: 11964989
    Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 20, 2022
    Date of Patent: April 23, 2024
    Assignees: Mirati Therapeutics, Inc., Array BioPharma Inc.
    Inventors: Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith, Shelley Allen, James F. Blake, Mark Joseph Chicarelli, Joshua Ryan Dahlke, Donghua Dai, Jay Bradford Fell, John Peter Fischer, Macedonio J. Mejia, Brad Newhouse, Phong Nguyen, Jacob Matthew O'Leary, Spencer Pajk, Martha E. Rodriguez, Pavel Savechenkov, Tony P. Tang, Guy P.A. Vigers, Qian Zhao, Dean Russell Kahn, John Gaudino, Michael Christopher Hilton
  • KRAS G12C INHIBITORS
    Publication number: 20240101553
    Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
    Type: Application
    Filed: August 4, 2023
    Publication date: March 28, 2024
    Inventors: Matthew Arnold MARX, James Gail CHRISTENSEN, Christopher Ronald SMITH, James F. BLAKE, Laurence E. BURGESS, Mark Joseph CHICARELLI, Adam COOK, Jay Bradford FELL, John P. FISCHER, Macedonio J. MEJIA, Martha E. RODRIGUEZ, Pavel SAVECHENKOV, Tony P. TANG, Guy P.A. VIGERS
  • Ladder system including a caster bracket and method of forming
    Patent number: 5653306
    Abstract: A ladder system comprising a ladder having side rails and a plurality of steps disposed between the side rails. The ladder system also is comprised of at least one corner brace for supporting a bottom step of the ladder. The corner brace is attached to a side rail of the ladder and the bottom step. Additionally, the ladder system is comprised of at least one caster assembly integrally attached to the corner brace for allowing the ladder to roll. Preferably, the caster assembly and corner brace are disposed on the ladder such that a predetermined weight placed on the ladder prevents the ladder from rolling. The corner brace is preferably comprised of a first portion, a second portion connected to the first portion and a third portion connected to the second portion. The first portion is attached to a bottom of the ladder. The second portion is attached to the caster assembly. Additionally, the third portion is attached to a rail of the ladder.
    Type: Grant
    Filed: March 6, 1996
    Date of Patent: August 5, 1997
    Assignee: Werner Co.
    Inventors: Roy B. Bendickson, Jay P. Smith