Patents by Inventor Jay W. Warrick
Jay W. Warrick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11724262Abstract: A device and method are provided to facilitate the handling of a volume of fluid. The device includes an elongated tube having an open first end and a second end. The tube defines a reservoir for receiving the volume of fluid. A stanchion has a first end received within the reservoir of the tube and a second end projecting from the open end of the elongated tube. In operation, the elongated tube is deposited in a first capsule having fluid therein. The first capsule is centrifuged such that the volume of fluid is received in a reservoir in the tube through the open end. The tube is removed from the first capsule and positioned in a second capsule such that the open end of the tube is spaced from a closed end of the second capsule. The second capsule is centrifuged such that the volume of fluid is expelled from the reservoir of the tube.Type: GrantFiled: September 25, 2020Date of Patent: August 15, 2023Assignee: Wisconsin Alumni Research FoundationInventors: David J. Beebe, Jay W. Warrick, David J. Guckenberger, Jr.
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Publication number: 20210016285Abstract: A device and method are provided to facilitate the handling of a volume of fluid. The device includes an elongated tube having an open first end and a second end. The tube defines a reservoir for receiving the volume of fluid. A stanchion has a first end received within the reservoir of the tube and a second end projecting from the open end of the elongated tube. In operation, the elongated tube is deposited in a first capsule having fluid therein. The first capsule is centrifuged such that the volume of fluid is received in a reservoir in the tube through the open end. The tube is removed from the first capsule and positioned in a second capsule such that the open end of the tube is spaced from a closed end of the second capsule. The second capsule is centrifuged such that the volume of fluid is expelled from the reservoir of the tube.Type: ApplicationFiled: September 25, 2020Publication date: January 21, 2021Inventors: David J. Beebe, Jay W. Warrick, David J. Guckenberger, JR.
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Patent number: 10807094Abstract: A device and method are provided to facilitate the handling of a volume or fluid. The device includes an elongated tube having an open first end and a second end. The tube defines a reservoir for receiving the volume or fluid. A stanchion has a first end received within the reservoir of the tube and a second end projecting from the open end of the elongated tube. In operation, the elongated tube is deposited in a first capsule having fluid therein. The first capsule is centrifuged such that the volume of fluid is received in a reservoir in the tube through the open end. The tube is removed from the first capsule and positioned in a second capsule such that the open end of the tube is spaced from a closed end of the second capsule. The second capsule is centrifuged such that the volume of fluid is expelled from the reservoir of the tube.Type: GrantFiled: September 27, 2016Date of Patent: October 20, 2020Assignee: Wisconsin Alumni Research FoundationInventors: David J. Beebe, Jay W. Warrick, David J. Guckenberger, Jr.
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Publication number: 20180085748Abstract: A device and method are provided to facilitate the handling of a volume or fluid. The device includes an elongated tube having an open first end and a second end. The tube defines a reservoir for receiving the volume or fluid. A stanchion has a first end received within the reservoir of the tube and a second end projecting from the open end of the elongated tube. In operation, the elongated tube is deposited in a first capsule having fluid therein. The first capsule is centrifuged such that the volume of fluid is received in a reservoir in the tube through the open end. The tube is removed from the first capsule and positioned in a second capsule such that the open end of the tube is spaced from a closed end of the second capsule. The second capsule is centrifuged such that the volume of fluid is expelled from the reservoir of the tube.Type: ApplicationFiled: September 27, 2016Publication date: March 29, 2018Inventors: David J. Beebe, Jay W. Warrick, David J. Guckenberger, JR.
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Patent number: 9867974Abstract: A device is provided for the administration of a compound in a body. The device includes a capsule having a reservoir therein for receiving the compound therein and a delivery instrument for positioning the capsule within the body. The delivery instrument includes a barrel having an interior adapted to receive the capsule therein and a dispersal element interacting with the barrel to selectively expel the capsule therefrom and into the body. A diffusion regulator communicates with the reservoir and controls the diffusion of the compound from the reservoir into the body. A retention structure projects from capsule and is configured to retain the capsule at a desired location within the body. Multiple devices may be used in conjunction to provide a multiplexed point source to administer multiple compounds simultaneously in vivo.Type: GrantFiled: June 1, 2015Date of Patent: January 16, 2018Assignee: Wisconsin Alumni Research FoundationInventors: David J. Beebe, Mark E. Burkard, Jay W. Warrick, David J Guckenberger, Lee G. Wilke
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Publication number: 20160346524Abstract: A device is provided for the administration of a compound in a body. The device includes a capsule having a reservoir therein for receiving the compound therein and a delivery instrument for positioning the capsule within the body. The delivery instrument includes a barrel having an interior adapted to receive the capsule therein and a dispersal element interacting with the barrel to selectively expel the capsule therefrom and into the body. A diffusion regulator communicates with the reservoir and controls the diffusion of the compound from the reservoir into the body. A retention structure projects from capsule and is configured to retain the capsule at a desired location within the body. Multiple devices may be used in conjunction to provide a multiplexed point source to administer multiple compounds simultaneously in vivo.Type: ApplicationFiled: June 1, 2015Publication date: December 1, 2016Inventors: David J. Beebe, Mark E. Burkard, Jay W. Warrick, David J. Guckenberger, Lee G. Wilke
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Patent number: 8945486Abstract: A microwell device is provided. The device includes a plate having a upper surface. The upper surface has first and second recesses formed therein. Each recess has an outer periphery. First and second portions of microwells are formed in upper surface of the plate. The first portion of microwells are spaced about the outer periphery of the first recess and the second portion of microwells spaced about the outer periphery of the first recess. A first barrier is about a first portions of the microwells for fluidicly isolating the first portion of the microwells and a second barrier about a second portions of microwells for fluidicly isolating the second portion of the microwells.Type: GrantFiled: March 8, 2013Date of Patent: February 3, 2015Assignee: Wisconsin Alumni Research FoundationInventors: Jay W. Warrick, John Yin, Stephen M. Lindsay
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Publication number: 20140255276Abstract: A microwell device is provided. The device includes a plate having a upper surface. The upper surface has first and second recesses formed therein. Each recess has an outer periphery. First and second portions of microwells are formed in upper surface of the plate. The first portion of microwells are spaced about the outer periphery of the first recess and the second portion of microwells spaced about the outer periphery of the first recess. A first barrier is about a first portions of the microwells for fluidicly isolating the first portion of the microwells and a second barrier about a second portions of microwells for fluidicly isolating the second portion of the microwells.Type: ApplicationFiled: March 8, 2013Publication date: September 11, 2014Applicant: Wisconsin Alumni Research FoundationInventors: Jay W. Warrick, John Yin, Stephen M. Lindsay
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Patent number: 8652852Abstract: A method is provided for pumping fluid through a channel of a microfluidic device. The channel has an input port and an output port. The channel is filled with fluid and a pressure gradient is generated between the fluid at the input port and the fluid at the output port. As a result, fluid flows through the channel towards the output port.Type: GrantFiled: October 13, 2011Date of Patent: February 18, 2014Assignee: Wisconsin Alumni Research FoundationInventors: David J. Beebe, Jay W. Warrick, Michael W. Toepke, Ivar Meyvantsson, Glenn M. Walker
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Patent number: 8389294Abstract: A microfluidic device and method is provided for coupling discrete channels and for co-culture. The microfluidic device includes first and second bodies. Each body has a bottom surface and defines a channel. The channel in each body includes an inlet and an outlet communicating with the bottom surface. A first fluid, such as a first cell suspension, is provided within the channel of the first body and a second fluid, such a second cell suspension, is provided within the channel of the second body. The first and second bodies are movable between a first position wherein the outlet of the channel of the first body is spaced from the inlet of the channel of the second body and a second position wherein the fluid at the outlet of the channel of the first body communicates with the fluid at the inlet of the channel of the second body.Type: GrantFiled: June 9, 2008Date of Patent: March 5, 2013Assignee: Wisconsin Alumni Research FoundationInventors: David J. Beebe, Jay W. Warrick
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Publication number: 20120051947Abstract: A method is provided for pumping fluid through a channel of a microfluidic device. The channel has an input port and an output port. The channel is filled with fluid and a pressure gradient is generated between the fluid at the input port and the fluid at the output port. As a result, fluid flows through the channel towards the output port.Type: ApplicationFiled: October 13, 2011Publication date: March 1, 2012Inventors: David J. Beebe, Jay W. Warrick, Michael W. Toepke, Ivar Meyvantsson, Glenn M. Walker
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Patent number: 8053249Abstract: A method is provided for pumping fluid through a channel of a microfluidic device. The channel has an input port and an output port. The channel is filled with fluid and a pressure gradient is generated between the fluid at the input port and the fluid at the output port. As a result, fluid flows through the channel towards the output port.Type: GrantFiled: March 12, 2007Date of Patent: November 8, 2011Assignee: Wisconsin Alumni Research FoundationInventors: David J. Beebe, Jay W. Warrick, Michael W. Toepke, Ivar Meyvantsson, Glenn M. Walker
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Publication number: 20100288368Abstract: A method is provided for pumping fluid through a channel of a microfluidic device. The channel has an input port and an output port. The channel is filled with fluid and a pressure gradient is generated between the fluid at the input port and the fluid at the output port. As a result, fluid flows through the channel towards the output port.Type: ApplicationFiled: March 12, 2007Publication date: November 18, 2010Inventors: David J. Beebe, Jay W. Warrick, Michael W. Toepke, Ivar Meyvantsson, Glenn M. Walker
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Publication number: 20090305326Abstract: A microfluidic device and method is provided for coupling discrete channels and for co-culture. The microfluidic device includes first and second bodies. Each body has a bottom surface and defines a channel. The channel in each body includes an inlet and an outlet communicating with the bottom surface. A first fluid, such as a first cell suspension, is provided within the channel of the first body and a second fluid, such a second cell suspension, is provided within the channel of the second body. The first and second bodies are movable between a first position wherein the outlet of the channel of the first body is spaced from the inlet of the channel of the second body and a second position wherein the fluid at the outlet of the channel of the first body communicates with the fluid at the inlet of the channel of the second body.Type: ApplicationFiled: June 9, 2008Publication date: December 10, 2009Inventors: David J. Beebe, Jay W. Warrick