Patents by Inventor Jayesh Dharia
Jayesh Dharia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230405551Abstract: A method for producing a chromatography medium by: a) exposing a nanoweb sheet having mean flow pore size from 0.1 to 5 ?m and a porosity from 40 to 90 volume % to a gaseous phase comprising a vinyl monomer to produce a functionalized nanoweb sheet; b) layering a plurality of functionalized nanoweb sheets to form a functionalized nanoweb stack; c) cutting the functionalized nanoweb stack with a die to form die-cut functionalized nanoweb stacks having regular shapes; and d) exposing the die-cut functionalized nanoweb stacks in an aqueous medium to a ligand such as a protein which is capable of forming covalent bonds.Type: ApplicationFiled: May 17, 2023Publication date: December 21, 2023Applicant: DDP SPECIALTY ELECTRONIC MATERIALS US, LLCInventors: Jayesh Dharia, Michael Ostrander
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Patent number: 7396465Abstract: The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.Type: GrantFiled: May 1, 2007Date of Patent: July 8, 2008Assignee: Pall CorporationInventors: Xiaosong Wu, Chung-Jen Hou, Jayesh Dharia, Peter Konstantin, Yujing Yang
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Publication number: 20070207493Abstract: The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.Type: ApplicationFiled: May 1, 2007Publication date: September 6, 2007Applicant: PALL CORPORATIONInventors: Xiaosong WU, Chung-Jen HOU, Jayesh DHARIA, Peter KONSTANTIN, Yujing YANG
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Patent number: 7223341Abstract: The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.Type: GrantFiled: July 6, 2006Date of Patent: May 29, 2007Assignee: Pall CorporationInventors: Xiaosong Wu, Chung-Jen Hou, Jayesh Dharia, Peter Konstantin, Yujing Yang
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Publication number: 20060249445Abstract: The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.Type: ApplicationFiled: July 6, 2006Publication date: November 9, 2006Applicant: Pall CorporationInventors: Xiaosong Wu, Chung-Jen Hou, Jayesh Dharia, Peter Konstantin, Yujing Yang
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Patent number: 7094347Abstract: The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.Type: GrantFiled: January 18, 2005Date of Patent: August 22, 2006Assignee: Pall CorporationInventors: Xiaosong Wu, Chung-Jen Hou, Jayesh Dharia, Peter Konstantin, Yujing Yang
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Publication number: 20050211621Abstract: The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.Type: ApplicationFiled: January 18, 2005Publication date: September 29, 2005Applicant: Pall CorporationInventors: Xiaosong Wu, Chung-Jen Hou, Jayesh Dharia, Peter Konstantin, Yujing Yang
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Patent number: 6851561Abstract: The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.Type: GrantFiled: July 15, 2004Date of Patent: February 8, 2005Assignee: Pall CorporationInventors: Xiaosong Wu, Chung-Jen Hou, Jayesh Dharia, Peter Konstantin, Yujing Yang
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Publication number: 20040251193Abstract: The present invention provides a positively charged microporous membrane having a protein binding capacity of about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.Type: ApplicationFiled: July 15, 2004Publication date: December 16, 2004Applicant: Pall CorporationInventors: Xiaosong Wu, Chung-Jen Hou, Jayesh Dharia, Peter Konstantin, Yujing Yang
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Patent number: 6780327Abstract: The present invention provides a positively charged microporous membrane having a protein binding capacity about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.Type: GrantFiled: December 12, 2001Date of Patent: August 24, 2004Assignee: Pall CorporationInventors: Xiaosong Wu, Chung-Jen Hou, Jayesh Dharia, Peter Konstantin, Yujing Yang
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Patent number: 5552551Abstract: Proton-transfer, low self-absorbing chromophores of the formula: ##STR1## wherein R.sub.2 and R.sub.3 are independently hydrogen, alkyl, aryl, cyano, nitro, halo or an ether group, R.sub.4 is O or N--H, and R.sub.5 is thienyl, naphthyl, furanyl, pyrrolyl, phenyl vinyl, diphenyl vinyl, phenyl ethynyl, hydroxy chromonyl phenyl, didecyloxy hydroxy chromonyl phenyl, phenyl or ##STR2## wherein R.sub.1 is vinyl, vinyl phenyl, vinyl benzyl, alkyl ethenyl, or alkyl phenyl ethenyl, provided that when R.sub.5 is phenyl and R.sub.2 and R.sub.3 are hydrogen, R.sub.4 is N--H.Type: GrantFiled: July 26, 1995Date of Patent: September 3, 1996Assignee: Florida State UniversityInventors: Joseph B. Schlenoff, Kurtis F. Johnson, Jayesh Dharia, Feng Gao
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Patent number: 5258478Abstract: Polymers containing covalently-bonded, low self-absorbing, scintillating chromophores, polymerizable chromophores of the formula: ##STR1## wherein R.sub.1 is vinyl, .alpha.-methyl vinyl, vinyl phenyl, or vinyl benzyl, and R.sub.2 and R.sub.3 are independently hydrogen, alkyl, aryl, cyano, nitro, halo, or ether, and a process for the preparation of polymers containing low self-absorbing, scintillating chromophores.Type: GrantFiled: April 27, 1992Date of Patent: November 2, 1993Assignee: Florida State UniversityInventors: Joseph B. Schlenoff, Jayesh Dharia, Kurtis F. Johnson