Patents by Inventor Jean-Antoine RIBEIL

Jean-Antoine RIBEIL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF BETA-THALASSEMIA
    Publication number: 20160368975
    Abstract: Methods and compositions for the treatment of ?-thalassemia are provided. Methods and compositions restore or increase erythrocyte maturation in individuals afflicted with ?-TM by preventing proteolysis of GATA-1 protein. Screening methods for identifying agents which bind heat shock protein 70 (HSP-70) and inhibit HSP-70 ?-globin binding, but which allow GATA-1 protein-HSP-1 binding in a manner that prevents GATA-1 proteolysis.
    Type: Application
    Filed: May 23, 2016
    Publication date: December 22, 2016
    Inventors: Olivier HERMINE, Genevieve COURTOIS, Jean-Benoit ARLET, Jean-Antoine RIBEIL
  • Methods and compositions for the treatment of ?-thalassemia
    Patent number: 9377471
    Abstract: Methods and compositions for the treatment of ?-thalassemia are provided. Methods and compositions restore or increase erythrocyte maturation in individuals afflicted with ?-TM by preventing proteolysis of GATA-1 protein. Screening methods for identifying agents which bind heat shock protein 70 (HSP-70) and inhibit HSP-70 ?-globin binding, but which allow GATA-1 protein-HSP-1 binding in a manner that prevents GATA-1 proteolysis.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: June 28, 2016
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), Universite Paris Descartes—Paris V, Assistance Publique—Hopitaux de Paris, Fondation Imagine
    Inventors: Olivier Hermine, Genevieve Courtois, Jean-Benoit Arlet, Jean-Antoine Ribeil
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF BETA-THALASSEMIA
    Publication number: 20150141341
    Abstract: Methods and compositions for the treatment of ?-thalassemia are provided. Methods and compositions restore or increase erythrocyte maturation in individuals afflicted with ?-TM by preventing proteolysis of GATA-1 protein. Screening methods for identifying agents which bind heat shock protein 70 (HSP-70) and inhibit HSP-70 ?-globin binding, but which allow GATA-1 protein-HSP-1 binding in a manner that prevents GATA-1 proteolysis.
    Type: Application
    Filed: November 19, 2014
    Publication date: May 21, 2015
    Inventors: Olivier HERMINE, Genevieve COURTOIS, Jean-Benoit ARLET, Jean-Antoine RIBEIL