Abstract: Cosmetic treatment method for adding fibers to natural eyelashes, comprising: a) applying an adhesive composition (A) to at least part of the eyelashes, b) bringing fibers (12) borne by an applicator (10) into contact with said adhesive composition (A) present on said eyelashes, c) moving the applicator (10) away from the eyelashes, so as to release fibers (12) which adhere to said eyelashes.

Abstract: Method for manufacturing a personalized applicator for applying a cosmetic composition to the lips, in which the applicator includes an application surface made from a material that can become loaded with composition. The method includes the following steps: a) performing a 3D scan of the topography of at least part of the surface of the lips, and b) from at least said scan, creating at least part of the applicator or a mold used for the manufacture thereof, by machining a preform or by additive manufacturing.

Abstract: The invention provides novel imidazopyrazine derivatives having the general formula (I), or pharmaceutically acceptable salts thereof, wherein X and R3 to R9 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: Method for manufacturing a personalized applicator for applying a product, notably make-up product, to keratinous materials, including a application surface. The method includes the following steps: a) applying to a surface of the keratinous materials of an individual a composition that modifies the appearance thereof, b) performing an optical acquisition of the topography of the surface thus covered and of at least one image providing information as to the location of the composition, and c) from this acquisition creating the applicator or a mold intended for the manufacture thereof.

Abstract: Provided are novel imidazopyrazine derivatives having the general formula (I), wherein A and R1 to R14 are as described herein and pharmaceutically acceptable salts thereof. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: Provided are novel imidazopyrazine derivatives having the general formula (I), wherein R1 to R11 are as described herein and pharmaceutically acceptable salts thereof. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and related diseases.

Abstract: A cosmetic treatment method including the steps of (a) applying an adhesive to an area of the scalp, (b) applying fibres to said area covered with adhesive, belonging to a bunch of at least 50 entangled fibres, said bunch including fibres having, at least over part of their length, a radius of curvature of between 1 and 10 mm, preferably between 1 and 5 mm, the application taking place in such a way that for at least some of the fibres of the bunch, they only come into contact with the adhesive over part of their length.

Abstract: A make-up and/or make-up assistance device comprising a support (21) configured to be positioned on the face and at least one make-up application and/or assistance component (22) supported by the support (21), wherein the shape of the support (21) is substantially adapted to the morphology of a predefined zone of the face and wherein the make-up application and/or assistance component (22) is adjustably connected to the support (21) so as to allow its position relative to the support (21) to be modified.

Abstract: A device for picking up and applying a cosmetic composition, in particular makeup, having a flexible support defining an, in particular continuous, application surface intended to receive the cosmetic composition, and at least two elements that are movable with respect to one another and are connected to the support, such that a relative movement of these two elements brings about a mechanical stress on the support and causes the latter to deform between a configuration for picking up cosmetic composition and an application configuration.

Abstract: A device for applying a cosmetic composition, in particular a makeup or care composition, to an application zone of a user, having a positioning system comprising at least one support configured to be positioned on a predefined supporting zone of the user's body and at least one connecting member connected to an application system for the composition, the support having a customized shape, adapted to said supporting zone, and/or the connecting member having a customized shape and/or dimensions, adapted to the morphology of the user, the device being configured to guide the connecting member, in particular to impose a predefined trajectory on said connecting member, when the latter is moved relative to said supporting zone from a position in which the support is positioned on said zone, in order to bring the application system into contact with said application zone.

Abstract: A cosmetic treatment method. The method includes creating, on a region of the keratin materials to be treated, a set of adhesive areas and of non-adhesive areas extending between the adhesive areas. The method includes electrostatically projecting fibres onto the region.

Abstract: The disclosure provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X1, RA and R3 to R7 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: Assembly comprising a spray means, preferably an airbrush comprising a pickup chamber subjected to a stream of entrainment air, and a dispenser comprising at least two compartments containing different base products, the compartments being pressurized by way of volumetric dosing devices, and the products being delivered to the spray means preferably via distinct dispensing orifices.

Abstract: An applicator for applying at least one fibre to human keratin materials, and in particular for filling out and/or lengthening the eyelashes or eyebrows. The applicator includes at least one channel into which a fibre is inserted, and this channel is defined by at least one portion that, in section, entirely surrounds the fibre and has at least one end-of-travel stop that limits the insertion of the fibre.

Abstract: The present invention relates to an assembly including at least one cosmetic composition for the cosmetic treatment of eyelashes or eyebrows, and a device including a mould having two mould parts to be closed on the eyelashes, with at least one of these parts having a concave groove, which is concave towards the proximal edge of the mould, especially curvilinear, allowing the formation of a strip of composition connecting at least part of the eyelashes along the eyelid or the eyebrow arch.

Abstract: The present invention relates to a dispensing system (10) comprising an assembly having a dispenser (11) of at least one cosmetic product, in particular makeup, and having at least two outlet interfaces (110), each of which can be mounted removably on the dispenser, the dispenser having at least two different base products and allowing these to be delivered in variable proportions, the outlet interfaces being able to receive the one or more products delivered by the dispenser.

Abstract: The present invention relates to a dispensing system (10) comprising an assembly having a dispenser (11) of at least one cosmetic product, in particular makeup, and having at least two outlet interfaces (110), each of which can be mounted removably on the dispenser, the dispenser having at least two different base products and allowing these to be delivered in variable proportions, the outlet interfaces being able to receive the one or more products delivered by the dispenser.

Abstract: Method for manufacturing a personalized applicator for applying a product, notably make-up product, to keratinous materials, including a application surface. The method includes the following steps: a) applying to a surface of the keratinous materials of an individual a composition that modifies the appearance thereof, b) performing an optical acquisition of the topography of the surface thus covered and of at least one image providing information as to the location of the composition, and c) from this acquisition creating the applicator or a mold intended for the manufacture thereof.

Abstract: The disclosure provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X1, RA and R3 to R7 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: Method for manufacturing a personalized applicator for applying a cosmetic composition to the lips, in which the applicator includes an application surface made from a material that can become loaded with composition. The method includes the following steps: a) performing a 3D scan of the topography of at least part of the surface of the lips, and b) from at least said scan, creating at least part of the applicator or a mold used for the manufacture thereof, by machining a preform or by additive manufacturing.