Patents by Inventor Jean-Christophe Antoine

Jean-Christophe Antoine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-ARGONAUTE PROTEIN AUTOANTIBODIES AS BIOMARKERS OF AUTOIMMUNE NEUROLOGICAL DISEASES
    Publication number: 20230314426
    Abstract: The invention relates to a process for identifying patients affected by an autoimmune neurological disease, comprising a step of detection of at least one type of anti-Argonaute autoantibodies (AGO-Abs) in a biological sample of an individual susceptible to be affected by said disease, wherein positive detection of said at least one type of AGO-Abs means that said individual is affected by said autoimmune neurological disease.
    Type: Application
    Filed: September 14, 2021
    Publication date: October 5, 2023
    Inventors: Le Duy DO, Jerome HONNORAT, Anne-Laurie PINTO, Christian Peter MORITZ, Jean-Christophe ANTOINE, Jean-Philippe CAMDESSANCHE, Sergio MUNIZ-CASTRILLO
  • Fibroblast growth factor receptors as diagnostic markers of acquired sensory neuronopathies
    Patent number: 10539577
    Abstract: The present invention relates to the diagnosis of acquired sensory neuronopathies (SNN), and to the treatment of these disorders.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: January 21, 2020
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE JEAN MONNET SAINT ETIENNE, UNIVERSITE CLAUDE BERNARD LYON 1, HOSPICES CIVILS DE LYON, CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT ETIENNE
    Inventors: Jerome Marc Claude Honnorat, Jean-Christophe Antoine, Jean-Philippe Camdessanche, Nadia Boutahar, Veronique Annie Rogemond
  • NOVEL HUMAN ULIP/CRMP PROTEIN AND USE THEREOF IN DIAGNOSIS AND TREATMENT OF CANCERS AND PARANEOPLASTIC NEUROLOGICAL SYNDROMES
    Publication number: 20190119339
    Abstract: A purified polypeptide, designated ULIP6, comprising the amino acid sequence SED ID No. 2 or an epitopic fragment of said polypeptide, comprising the sequence SEQ ID No. 4, is provided along with its nucleic acid sequences. In addition, antibodies to the polypeptide and methods of diagnosing paraneoplastic neurological syndromes and/or for the early diagnosis of the formation of cancerous tumors are also provided.
    Type: Application
    Filed: September 12, 2018
    Publication date: April 25, 2019
    Inventors: Michele AGUERA, Jean-Christophe ANTOINE, Marie-Francoise BELIN, Jerome HONNORAT, Veronique ROGEMOND
  • Human ULIP/CRMP protein and use thereof in diagnosis and treatment of cancers and paraneoplastic neurological syndromes
    Patent number: 10087220
    Abstract: A purified polypeptide, designated ULIP6, comprising the amino acid sequence SEQ ID No. 2 or an epitopic fragment of said polypeptide, comprising the sequence SEQ ID No. 4, is provided along with its nucleic acid sequences. In addition, antibodies to the polypeptide and methods of diagnosing paraneoplastic neurological syndromes and/or for the early diagnosis of the formation of cancerous tumors are also provided.
    Type: Grant
    Filed: January 15, 2013
    Date of Patent: October 2, 2018
    Assignee: INSTITUT NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Michele Aguera, Jean-Christophe Antoine, Marie-Francoise Belin, Jerome Honnorat, Veronique Rogemond
  • FIBROBLAST GROWTH FACTOR RECEPTORS AS DIAGNOSTIC MARKERS OF ACQUIRED SENSORY NEURONOPATHIES
    Publication number: 20170343564
    Abstract: The present invention relates to the diagnosis of acquired sensory neuronopathies (SNN), and to the treatment of these disorders.
    Type: Application
    Filed: July 26, 2017
    Publication date: November 30, 2017
    Inventors: Jerome Marc Claude HONNORAT, Jean-Christophe ANTOINE, Jean-Philippe CAMDESSANCHE, Nadia BOUTAHAR, Veronique Annie ROGEMOND
  • Fibroblast growth factor receptors as diagnostic markers of acquired sensory neuronopathies
    Patent number: 9766253
    Abstract: The present invention relates to the diagnosis of acquired sensory neuronopathies (SNN), and to the treatment of these disorders.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: September 19, 2017
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique, Universite Jean Monnet, Universite Claude Bernard Lyon 1, Hospices Civils de Lyon, Centre Hospitalier Universitaire de Saint Etienne
    Inventors: Jerome Marc Claude Honnorat, Jean-Christophe Antoine, Jean-Philippe Camdessanche, Nadia Boutahar, Veronique Annie Rogemond
  • FIBROBLAST GROWTH FACTOR RECEPTORS AS DIAGNOSTIC MARKERS OF ACQUIRED SENSORY NEURONOPATHIES
    Publication number: 20150192594
    Abstract: The present invention relates to the diagnosis of acquired sensory neuronopathies (SNN), and to the treatment of these disorders.
    Type: Application
    Filed: June 28, 2013
    Publication date: July 9, 2015
    Inventors: Jerome Marc Claude Honnorat, Jean-Christophe Antoine, Jean-Philippe Camdessanche, Nadia Boutahar, Veronique Annie Rogemond
  • Diagnosis of cancers and paraneoplastic neurological syndromes with novel human ULIP/CRMP protein
    Patent number: 8377645
    Abstract: A purified polypeptide, designated ULIP6, comprising the amino acid sequence SEQ ID No. 2 or an epitopic fragment of said polypeptide, comprising the sequence SEQ ID No. 4, is provided along with its nucleic acid sequences. In addition, antibodies to the polypeptide and methods of diagnosing paraneoplastic neurological syndromes and/or for the early diagnosis of the formation of cancerous tumors are also provided.
    Type: Grant
    Filed: February 11, 2008
    Date of Patent: February 19, 2013
    Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Michèle Aguera, Jean-Christophe Antoine, Marie-Françoise Belin, Jérôme Honnorat, Véronique Rogemond
  • Use of a protein of the CRMP family for treating diseases related to the immune system
    Patent number: 7820375
    Abstract: The invention concerns the use of at least a protein of the CRMP family, a polypeptide fragment or an active biological derivative thereof, a nucleotide sequence or sequence fragment coding for said protein, an antisense sequence capable of being specifically hybridized with a sequence with nucleotide-type encoding of said protein or an antibody directed against said protein for producing a medicine for treating diseases related to a dysfunction of the immune system. The invention also concerns a method for diagnosing an autoimmune pathology which consists in measuring the expression of a CRMP protein in the lymphocytes.
    Type: Grant
    Filed: September 9, 2002
    Date of Patent: October 26, 2010
    Assignee: Institut National de la Sante Et de la Recherche Medicale (Inserm)
    Inventors: Pascale Giraudon, Marie-Françoise Belin, Christophe Malcus, Pierre Colas, Jean-Christophe Antoine, Jérôme Honnorat
  • Novel human ulip/CRMP protein and use thereof in diagnosis and treatment of cancers and paraneoplastic neurological syndromes
    Publication number: 20080226636
    Abstract: A purified polypeptide, designated ULIP6, comprising the amino acid sequence SEQ ID No. 2 or an epitopic fragment of said polypeptide, comprising the sequence SEQ ID No. 4, is provided along with its nucleic acid sequences. In addition, antibodies to the polypeptide and methods of diagnosing paraneoplastic neurological syndromes and/or for the early diagnosis of the formation of cancerous tumors are also provided.
    Type: Application
    Filed: February 11, 2008
    Publication date: September 18, 2008
    Inventors: Michele Aguera, Jean-Christophe Antoine, Marie-Francoise Belin, Jerome Honnorat, Veronique Rogemond
  • Use of a novel human ULIP6/CRMP protein in diagnosis of paraneoplastic neurological syndromes
    Patent number: 7329499
    Abstract: The invention concerns a purified polypeptide, called ULIP6, comprising an amino acid sequence SEQ ID NO 2, the nucleic acid coding for said polypeptide, a non-coding sequence in 3? of said encoding sequence and their use in diagnosis and treatment of cancers and paraneoplastic neurological syndromes.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: February 12, 2008
    Assignee: Institut National de la Sante et de la Recherche Medicale (Inserm)
    Inventors: Michèle Aguera, Jean-Christophe Antoine, Marie-Françoise Belin, Jérôme Honnorat, Véronique Rogemond
  • Use of ULIP proteins in the diagnosis and therapy of cancers and paraneoplastic neurological syndromes
    Publication number: 20070117166
    Abstract: The invention relates to the use of proteins designated ULIP/POP in the diagnosis and therapy of cancers and paraneoplastic neurological syndromes.
    Type: Application
    Filed: December 20, 2006
    Publication date: May 24, 2007
    Inventors: Michele Aguera, Marie-Francoise Belin, Jerome Honnorat, Pappachan Kolattukudy, ThanhTam Quach, Tamara Byk, Andre Sobel, Dominique Aunis, Jean-Christophe Antoine
  • Use of ULIP proteins in the diagnosis and therapy of cancers and paraneoplastic neurological syndromes
    Patent number: 7183400
    Abstract: The invention concerns a purified polypeptide, biologically active polypeptide derivative or fragment of said purified polypeptide, comprising an amino acid sequence selected among SEQ.ID. No. 2, No. 4, No. 6 and No. 8.
    Type: Grant
    Filed: February 19, 1998
    Date of Patent: February 27, 2007
    Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Michèle Aguera, Marie-Françoise Belin, Jérôme Honnorat, Pappachan Kolattukudy, ThanhTam Quach, Tamara Byk, André Sobel, Dominique Aunis, Jean-Christophe Antoine
  • Use of a protein of the crmp family for treating diseases related to the immune system
    Publication number: 20050106143
    Abstract: The invention concerns the use of at least a protein of the CRMP family, a polypeptide fragment or an active biological derivative thereof, a nucleotide sequence or sequence fragment coding for said protein, an antisense sequence capable of being specifically hybridized with a sequence with nucleotide-type encoding of said protein or an antibody directed against said protein for producing a medicine for treating diseases related to a dysfunction of the immune system. The invention also concerns a method for diagnosing an autoimmune pathology which consists in measuring the expression of a CRMP protein in the lymphocytes.
    Type: Application
    Filed: September 9, 2002
    Publication date: May 19, 2005
    Inventors: Pascale Giraudon, Marie-Francoise Belin, Christophe Malcus, Pierre Colas, Jean-Christophe Antoine, Jerome Honnorat
  • Novel human ulip/crmp protein and use thereof in diagnosis and treatment of cancers and paraneoplastic neurological syndromes
    Publication number: 20030176336
    Abstract: The invention concerns a purified polypeptide, called ULIP6, comprising an amino acid sequence SEQ ID NO 2, the nucleic acid coding for said polypeptide, a non-coding sequence in 3′ of said encoding sequence and their use in diagnosis and treatment of cancers and paraneoplastic neurological syndromes.
    Type: Application
    Filed: November 19, 2002
    Publication date: September 18, 2003
    Inventors: Michele Aguera, Jean-Christophe Antoine, Marie-Francoise Belin, Jerome Honnorat, Veronique Rogemond